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CLINICAL BIOSTATS

Statistical Calculators

TITE-BOIN Calculator

TITE-BOIN Calculation Form TITE-BOIN Calculation Form Target: pTrue (comma separated): Number of Cohorts: Cohort Size: Maximum T: Accrual Rate: Maximum Penalty: Distribution

Simon’s Two Stage Design This program calculates optimal two-stage designs based on Simon’s methodology (Simon, 1989) and admissible designs as proposed by

Fleming’s Two Stage Design p0: pa: Alpha: Beta: Epsilon: N_min: N_max: Calculate Add Your Heading Text Here “On the other hand, we

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