Topic: Allometric Scaling and Maturation Functions

Worked Example: Scaling a Renally Cleared Drug

Why Age and Weight Effects Can Be Confounded

Why Clearance and Volume Need Different Scaling

Worked Example: Multiple Maturation Pathways

When Proportional Weight Scaling Misleads

Scaling Intercompartmental Clearance and Flow

Reference-Size Normalization in Allometric Models

Residual Diagnostics for Developmental Scaling

Prematurity and the Transition at Birth

Physiological Derivation of Clearance and Volume Exponents