Topic: Case Studies: Questions, Evidence and Decisions

Selecting a Dosing Interval for a Long-Acting Formulation

Propagating Uncertainty in an Interspecies PK Projection

Quantifying the Impact of Dropout in a Clinical Trial Simulation

Projecting Human Exposure With Target-Mediated Drug Disposition

Planning an Event-Driven Trial With Model-Based Event Projections

Planning Sample Size for Repeated-Measures Endpoints

Predicting a Time-Dependent Enzyme Induction Interaction

Modeling Exposure-Response for a Binary Clinical Outcome

Linking Drug Exposure to Neutropenia Risk

Making a Development Decision From Sparse Population PK Data