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Topic:
Clinical DDI Study Design and Quantitative Exposure Prediction
Defining DDI Exposure-Ratio Estimands
Control Periods and Baseline Exposure Measurement
Choosing Sensitive and Selective Probe Substrates
Cmax, Tmax, and Absorption-Phase Interpretation
Capturing Induction and Time-Dependent Inhibition
Aligning Victim Dosing With Pharmacokinetic Sampling
Active Metabolite and Total Active Moiety Endpoints
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