Analyzing Change from Baseline in Clinical Trials
A practical guide to analyzing change from baseline in clinical trials, including change scores, ANCOVA, repeated-measures models, MMRM, least-squares means, percent change, baseline adjustment, missing data, interpretation, and worked examples.
Analysis of Longitudinal Binary Outcomes
A practical guide to analyzing longitudinal binary outcomes in clinical research using GEE and generalized linear mixed models, including marginal versus subject-specific effects, working correlation structures, missing data, interpretation, R and SAS examples, and a complete worked example.