Topic: Obesity, Aging and Disease States

Worked Example: Comparing Young and Older Adult Physiology

Worked Example: Constructing an Obese-Adult Physiological Model

Worked Example: Encoding Chronic Heart Failure Physiology

Selecting Body-Size Descriptors for Obese Adults

Scaling Lean Mass and Organ Volumes in Obesity

Representing Adipose Expansion and Perfusion

Reallocating Cardiac Output in Obesity

Interpreting Exposure Residuals from Age-Dependent Physiology

Encoding Disease-Related Physiological Remodeling

Diagnosing Implausible Obesity-Related PBPK Inputs