Topic: One-, Two- and Three-Compartment Structural Models

Early Samples and the Fast Distribution Phase

Distribution and Terminal Phases in Two-Compartment Profiles

Diagnosing the Number of Exponential Phases

Deriving the Two-Compartment Eigenvalues

Converting CL, Q, Vc, and Vp to Rate Constants

Correlated Parameters and Equivalent Concentration Profiles

Confounding Between Intercompartmental Clearance and Peripheral Volume

Clearance, Volume, and the Elimination Rate Constant

Clearance-Volume Parameterization of the Three-Compartment Model

Clearance-Volume Parameterization of the Two-Compartment Model