Topic: Pregnancy and Lactation

Worked Case: Lactation Exposure and Sensitivity Analysis

Worked Case: Predicting Fetal Exposure Across Gestation

Testing Placental Models With Cord-Blood Samples

Pregnancy-Specific Changes in Drug Clearance

Placental Exchange Regimes and Model Choice

Maternal Binding and Hemodilution Across Gestation

Maternal Blood-Flow Remodeling During Pregnancy

Milk-to-Plasma Partitioning During Lactation

Interpreting Maternal-Fetal Concentration-Time Profiles

Gestational Trajectories for Maternal PBPK Parameters