Topic: Time-to-Event MAMS With Intermediate Outcomes

Repeated Measures Before Event Readout

Predictive Probability of Final Success

Prognostic Association With the Final Endpoint

Protocol Checklist for Intermediate-Based Selection

Power Definitions After Intermediate Selection

Operating Characteristics of Intermediate-Based Rules

Outcome Maturity at Selection Looks

Misclassification of Binary Intermediate Outcomes

Missing Intermediate Outcomes at the Selection Look

Multiple Intermediate Outcomes and Selection