Topic: Transporter-Mediated Interactions

Troubleshooting Implausible Transporter DDI Predictions

Selecting Transporter Substrates and Inhibitors from Evidence

Separating Transporter Inhibition from Enzyme-Mediated DDI Effects

Rosuvastatin-Cyclosporine Transporter DDI Case Study

Predicting Hepatic OATP1B1 and OATP1B3 Inhibition

Predicting Intestinal P-Glycoprotein and BCRP Inhibition

Modeling Hepatic Uptake-Efflux Interactions

Modeling Renal OAT, OCT, and MATE Interactions

Mapping Transporter-Mediated DDI Pathways

Interpreting Opposing Transporter Effects on Net Drug Exposure