Topic: Verification, Validation and Independent Validation

Worked Qualification Case: Independent Validation of a Cytokine Model

Validation Across Dose Levels and Regimens

Verifying Dosing Events and Discontinuous Inputs

Traceability Matrices for Qualification Evidence

Statistical Tests for Stochastic QSP Implementations

Selecting Validation Data for a Prediction Claim

Residual Diagnostics for Longitudinal QSP Predictions

Regression Tests for QSP Model Changes

Population-Level Validation of Virtual Cohort Predictions

Metamorphic Testing When No Exact Solution Exists