Topic: Why Multi-Arm Designs

When a Larger Control Group Is Worthwhile

Why a Shared Control Can Reduce Recruitment

Why Shared Controls Do Not Always Save Participants

Unequal Treatment Costs and Arm Allocation

The Structure of a Multi-Arm Trial

Shared-Control Efficiency for Continuous Outcomes

Separate Trials Versus One Multi-Arm Protocol

Shared-Control Efficiency for Binary Outcomes

Recruitment Cost Versus Participant Count

Precision at a Fixed Total Sample Size