Trials that use: Interim analysis / alpha spending
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3,081 results
- “Answers in Hours” A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures: Complete Statistical AnalysisIndependent statistical analysis of "Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- [F-18] Fluorothymidine (FLT) Imaging on Patients With Primary Brain Tumors: Complete Statistical AnalysisIndependent statistical analysis of [F-18] Fluorothymidine (FLT) Imaging on Patients With Primary Brain Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00707343).
- 0822GCC: Phase 2 Study of Efficacy and Safety of Apricoxib/Placebo With Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of 0822GCC: Phase 2 Study of Efficacy and Safety of Apricoxib/Placebo With Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…
- 1/2 A Multi-site Systems Intervention for Unemployed Persons With Social Anxiety: Complete Statistical AnalysisIndependent statistical analysis of 1/2 A Multi-site Systems Intervention for Unemployed Persons With Social Anxiety: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- 12 Month Open Extension of TNS for ADHD.: Complete Statistical AnalysisIndependent statistical analysis of 12 Month Open Extension of TNS for ADHD.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03888391).
- 12- Week Open Label Treatment of Refractory Bipolar Depression: Complete Statistical AnalysisIndependent statistical analysis of 12- Week Open Label Treatment of Refractory Bipolar Depression: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00223496).
- 12-Month Stability of Diurnal IOP Control on Cosopt: Complete Statistical AnalysisIndependent statistical analysis of 12-Month Stability of Diurnal IOP Control on Cosopt: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00379834).
- 15 mg Mirtazapine Orally Disintegrating Tablets, Non-Fasting: Complete Statistical AnalysisIndependent statistical analysis of 15 mg Mirtazapine Orally Disintegrating Tablets, Non-Fasting: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00834197).
- 1565GCCIndependent statistical analysis of Decitabine and Talazoparib in Untreated AML and R/R AML: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02878785).
- 17-AAG in Treating Patients With Relapsed or Refractory Anaplastic Large Cell Lymphoma, Mantle Cell Lymphoma, or Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of 17-AAG in Treating Patients With Relapsed or Refractory Anaplastic Large Cell Lymphoma, Mantle Cell Lymphoma, or Hodgkin's Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- 18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies: Complete Statistical AnalysisIndependent statistical analysis of 18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- 1974Independent statistical analysis of Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- 2-DeoxyglucoseIndependent statistical analysis of A Phase I/II Trial of 2-Deoxyglucose (2DG) for the Treatment of Advanced Cancer and Hormone Refractory Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- 2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD: Complete Statistical AnalysisIndependent statistical analysis of 2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01404208).
- 24-hour IOP-lowering Effect of 0.01% Bimatoprost: Complete Statistical AnalysisIndependent statistical analysis of 24-hour IOP-lowering Effect of 0.01% Bimatoprost: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01271686).
- 24-hour IOP-lowering Effect of Brimonidine 0.1%: Complete Statistical AnalysisIndependent statistical analysis of 24-hour IOP-lowering Effect of Brimonidine 0.1%: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00457795).
- 276Independent statistical analysis of A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- 28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study: Complete Statistical AnalysisIndependent statistical analysis of 28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00208507).
- 2CAREIndependent statistical analysis of Coenzyme Q10 in Huntington's Disease (HD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00608881).
- 3 Month Safety Study of Dymista Nasal Spray and Fluticasone Propionate in Children 4-11 Years of Age With Allergic Rhinitis: Complete Statistical AnalysisIndependent statistical analysis of 3 Month Safety Study of Dymista Nasal Spray and Fluticasone Propionate in Children 4-11 Years of Age With Allergic Rhinitis: primary endpoint results, effect estimate with confidence interval,…
- 306A/306BIndependent statistical analysis of A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- 337Independent statistical analysis of BrUOG 337: Olaparib Prior to Radical Prostatectomy For Advanced Prostate Cancer Defects in DNA Repair Genes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- 36-month Special Drug Use Surveillance on Frequency of Bone Fractures With Sodium Risedronate 75 mg Tablets: Complete Statistical AnalysisIndependent statistical analysis of 36-month Special Drug Use Surveillance on Frequency of Bone Fractures With Sodium Risedronate 75 mg Tablets: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- 3CIndependent statistical analysis of Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01120028).
- 3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes: Complete Statistical AnalysisIndependent statistical analysis of 3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- 3MVIndependent statistical analysis of Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- 4 Pillars Toolkit for Adolescent Vaccination: Complete Statistical AnalysisIndependent statistical analysis of 4 Pillars Toolkit for Adolescent Vaccination: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02165722).
- 5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of 5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- 52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period: Complete Statistical AnalysisIndependent statistical analysis of 52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- 64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer: Complete Statistical AnalysisIndependent statistical analysis of 64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01939275).
- 65plusIndependent statistical analysis of Efficacy Study of Avastin® With Pemetrexed +/- Carboplatin to Treat Elderly Patients With Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- 68Ga PSMA in Preprostatectomy Patients: Complete Statistical AnalysisIndependent statistical analysis of 68Ga PSMA in Preprostatectomy Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03388346).
- 8-week Randomized, Open-label Study to Evaluate Food Effect on Efficacy and Safety of Oral Aliskiren 300 mg in Patients With Hypertension: Complete Statistical AnalysisIndependent statistical analysis of 8-week Randomized, Open-label Study to Evaluate Food Effect on Efficacy and Safety of Oral Aliskiren 300 mg in Patients With Hypertension: primary endpoint results, effect estimate with confidence…
- 90° Rotation Technique for LMA FlexibleTM Insertion: Complete Statistical AnalysisIndependent statistical analysis of 90° Rotation Technique for LMA FlexibleTM Insertion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03028896).
- 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients: Complete Statistical AnalysisIndependent statistical analysis of 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A “Real World” Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM): Complete Statistical AnalysisIndependent statistical analysis of A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.: Complete Statistical AnalysisIndependent statistical analysis of A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD…
- A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation: Complete Statistical AnalysisIndependent statistical analysis of A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation: primary endpoint results,…
- A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY: Complete Statistical AnalysisIndependent statistical analysis of A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY: primary endpoint results,…
- A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children…
- A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica: Complete Statistical AnalysisIndependent statistical analysis of A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A 3-Month Open-Label Safety and Efficacy Study of TNX-102 SL Tablets in Fibromyalgia Patients: Complete Statistical AnalysisIndependent statistical analysis of A 3-Month Open-Label Safety and Efficacy Study of TNX-102 SL Tablets in Fibromyalgia Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD): Complete Statistical AnalysisIndependent statistical analysis of A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD): primary endpoint results, effect estimate with confidence interval, sample-size…
- A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease: Complete Statistical AnalysisIndependent statistical analysis of A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB): Complete Statistical AnalysisIndependent statistical analysis of A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Bioequivalence Study Comparing A Fixed Dose Combination Formulation, Rin 150 And Individual Reference Drugs In Healthy Volunteers: Complete Statistical AnalysisIndependent statistical analysis of A Bioequivalence Study Comparing A Fixed Dose Combination Formulation, Rin 150 And Individual Reference Drugs In Healthy Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Bioequivalence Study of Mirikizumab (LY3074828) in Healthy Participants: Complete Statistical AnalysisIndependent statistical analysis of A Bioequivalence Study of Mirikizumab (LY3074828) in Healthy Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05515601).
- A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Clinical Comparison of Two Daily Disposable Soft Contact Lenses: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Comparison of Two Daily Disposable Soft Contact Lenses: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04005885).