Trials that use: Interim analysis / alpha spending
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4,594 results
- A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202): Complete Statistical AnalysisIndependent statistical analysis of A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202): primary endpoint results, effect estimate with…
- A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN): Complete Statistical AnalysisIndependent statistical analysis of A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN): primary endpoint results, effect estimate with confidence…
- A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: Complete Statistical AnalysisIndependent statistical analysis of A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of Single and Multiple SC Doses of ALXN1830 in Healthy Adult Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study of Single and Multiple SC Doses of ALXN1830 in Healthy Adult Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer: primary endpoint results, effect…
- A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR): Complete Statistical AnalysisIndependent statistical analysis of A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function: Complete Statistical AnalysisIndependent statistical analysis of A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Soticlestat Tablets in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study of Soticlestat Tablets in Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05284760).
- A Study of Subcutaneous (sc) Mircera in Dialysis Patients With Chronic Renal Anemia.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Subcutaneous (sc) Mircera in Dialysis Patients With Chronic Renal Anemia.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77): Complete Statistical AnalysisIndependent statistical analysis of A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77): primary endpoint results,…
- A Study of Sunitinib in Combination With Bevacizumab and Paclitaxel in Previously Untreated Patients With Metastatic Breast Cancer (SABRE-B): Complete Statistical AnalysisIndependent statistical analysis of A Study of Sunitinib in Combination With Bevacizumab and Paclitaxel in Previously Untreated Patients With Metastatic Breast Cancer (SABRE-B): primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Tadalafil in Men With Benign Prostatic Hyperplasia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tadalafil in Men With Benign Prostatic Hyperplasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00970632).
- A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary Symptoms: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tadalafil Use With Finasteride in Men With Enlarged Prostates and Urinary Symptoms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Tarceva (Erlotinib) in Combination With Avastin (Bevacizumab) in Patients With Advanced Non-Small Cell Lung Cancer.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tarceva (Erlotinib) in Combination With Avastin (Bevacizumab) in Patients With Advanced Non-Small Cell Lung Cancer.: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer: primary endpoint…
- A Study of TAS-120 in Patients With Metastatic Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of TAS-120 in Patients With Metastatic Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04024436).
- A Study of Tasisulam in Treating Participants With Malignant Melanoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tasisulam in Treating Participants With Malignant Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00383292).
- A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older: Complete Statistical AnalysisIndependent statistical analysis of A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of the Bruton’s Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD): primary endpoint results, effect estimate with confidence…
- A Study of the Effect of Enantone LP 11.25 mg (Leuprorelin) on the Histological Progression of Indolent Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of Enantone LP 11.25 mg (Leuprorelin) on the Histological Progression of Indolent Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Effect of Food on Pirtobrutinib (LOXO-305) in Healthy Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of Food on Pirtobrutinib (LOXO-305) in Healthy Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of the Effect of LY2216684 on Lorazepam: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of LY2216684 on Lorazepam: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01275144).
- A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of the Effect of SYN-010 on Subjects With IBS-C: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of SYN-010 on Subjects With IBS-C: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That is Not Controlled by High Dose Inhaled Corticosteroid Asthma Medications: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That…
- A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: primary…
- A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.: primary endpoint…
- A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary…
- A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD): primary endpoint results, effect estimate…
- A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Crohn’s Disease Who Have Inadequately Responded to or Are Intolerant to Biologic Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to…
- A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01390441).
- A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate…
- A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Efficacy of Infliximab(REMICADE ) in Pediatric Patients With Moderately to SeverelyActive Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of Infliximab(REMICADE ) in Pediatric Patients With Moderately to SeverelyActive Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Efficacy of Injectable Risperidone in the Prevention of Bipolar Mood Episodes: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of Injectable Risperidone in the Prevention of Bipolar Mood Episodes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…