Trials that use: Interim analysis / alpha spending
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11,819 results
- Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics Study of Oral IXAZOMIB in Participants With Advanced Nonhematologic Malignancies or Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD): Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Pharmacokinetics, Metabolism, Efficacy, and Safety Study of Two Testosterone Matrix Transdermal Systems: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics, Metabolism, Efficacy, and Safety Study of Two Testosterone Matrix Transdermal Systems: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Pharmacological Effects of Crushing Prasugrel in STEMI Patients: Complete Statistical AnalysisIndependent statistical analysis of Pharmacological Effects of Crushing Prasugrel in STEMI Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02212028).
- PHASEIndependent statistical analysis of Effects of Sulforaphane on Normal Prostate Tissue: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00946309).
- Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG): Complete Statistical AnalysisIndependent statistical analysis of Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 1 Bioavailability Study of Apixaban Solution Formulation Relative to Apixaban Tablets in Healthy Subjects: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Bioavailability Study of Apixaban Solution Formulation Relative to Apixaban Tablets in Healthy Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 1 Clinical Trial of Single-Vial ID93 + GLA-SE in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Clinical Trial of Single-Vial ID93 + GLA-SE in Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 1 Study to Determine the Effects of Food on the Pharmacokinetic Profile of PBT2: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Study to Determine the Effects of Food on the Pharmacokinetic Profile of PBT2: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 1 Trial of Oral Ixabepilone: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Trial of Oral Ixabepilone: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00632424).
- Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas: Complete Statistical AnalysisIndependent statistical analysis of Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint results, effect…
- Phase 1/2 Study of BBT-176 in Advanced NSCLC With Progression After EGFR TKI Treatment: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2 Study of BBT-176 in Advanced NSCLC With Progression After EGFR TKI Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 1/2 Trial of Selinexor (KPT-330) With Docetaxel for Non-small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2 Trial of Selinexor (KPT-330) With Docetaxel for Non-small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 1/2a Safety and Efficacy of ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2a Safety and Efficacy of ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC): Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures: Complete Statistical AnalysisIndependent statistical analysis of Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 1b Dose Escalation Study of Intravenous JX-594 in Metastatic, Refractory Colorectal Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b Dose Escalation Study of Intravenous JX-594 in Metastatic, Refractory Colorectal Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 1b Study of DCR-AUD in Healthy Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b Study of DCR-AUD in Healthy Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05845398).
- Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1): primary endpoint results, effect estimate with confidence interval,…
- Phase 2 Chronic Low Back Pain Study: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Chronic Low Back Pain Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01364922).
- Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4): primary…
- Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4): primary…
- Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study in Vascular Inflammation on Patients After an Acute Coronary Syndrome Event: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study in Vascular Inflammation on Patients After an Acute Coronary Syndrome Event: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC): primary endpoint…
- Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study of Atorvastatin Safety and Antitumor Effects in Non-Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Atorvastatin Safety and Antitumor Effects in Non-Hodgkin's Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 2 Study of Belimumab Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus (SLE): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Belimumab Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus (SLE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00588146).
- Phase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00369681).
- Phase 2 Study of Rivaroxaban Reversal by Ciraparantag as Measured by WBCT: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Rivaroxaban Reversal by Ciraparantag as Measured by WBCT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…