Trials that use: Interim analysis / alpha spending
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11,819 results
- Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study to Evaluate RPT193 in Adults With Moderate to Severe T2-high Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy: primary endpoint results, effect estimate…
- Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence: Complete Statistical AnalysisIndependent statistical analysis of Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00687713).
- Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1): Complete Statistical AnalysisIndependent statistical analysis of Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1): primary endpoint results, effect estimate…
- Phase 2, Open-Label, Multi-Dose Study of Panhematin in Patients With MDS: Complete Statistical AnalysisIndependent statistical analysis of Phase 2, Open-Label, Multi-Dose Study of Panhematin in Patients With MDS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC): Complete Statistical AnalysisIndependent statistical analysis of Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase 2a Study of ZW25 in Combination With Palbociclib Plus Fulvestrant: Complete Statistical AnalysisIndependent statistical analysis of Phase 2a Study of ZW25 in Combination With Palbociclib Plus Fulvestrant: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects: Complete Statistical AnalysisIndependent statistical analysis of Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects: primary endpoint results, effect estimate with confidence…
- Phase 2B Study to Evaluate ASN002 in Subjects With Moderate to Severe Atopic Dermatitis (RADIANT): Complete Statistical AnalysisIndependent statistical analysis of Phase 2B Study to Evaluate ASN002 in Subjects With Moderate to Severe Atopic Dermatitis (RADIANT): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo: primary…
- Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL): Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 3 Efficacy and Safety Study in Adults With ADHD Using CTx-1301.: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Efficacy and Safety Study in Adults With ADHD Using CTx-1301.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 3 Papulopustular Rosacea Study: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Papulopustular Rosacea Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01493687).
- Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study Evaluating Efficacy, Safety and Pharmacokinetics of Trilaciclib In Small Cell Lung Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery: primary endpoint results, effect estimate with confidence interval, sample-size…
- Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area: primary endpoint results, effect estimate with confidence…
- Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 3 Study of OTO-201 in Acute Otitis Externa: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study of OTO-201 in Acute Otitis Externa: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02801370).
- Phase 3 Study of TAK-438 10 mg in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD): Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study of TAK-438 10 mg in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase 3/Safety & Efficacy of Esomeprazole in Infants: Complete Statistical AnalysisIndependent statistical analysis of Phase 3/Safety & Efficacy of Esomeprazole in Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00468559).
- Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection: Complete Statistical AnalysisIndependent statistical analysis of Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection: primary endpoint results, effect estimate with confidence interval,…
- Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE): Complete Statistical AnalysisIndependent statistical analysis of Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE): primary endpoint results, effect estimate with confidence interval, sample-size…
- Phase IIndependent statistical analysis of Electrical Stimulation for Critically Ill Covid-19 Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04685213).
- Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity: Complete Statistical AnalysisIndependent statistical analysis of Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase I Combination Ixabepilone + Cisplatin: Complete Statistical AnalysisIndependent statistical analysis of Phase I Combination Ixabepilone + Cisplatin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00832117).
- Phase I Combination w/ Epirubicin: Complete Statistical AnalysisIndependent statistical analysis of Phase I Combination w/ Epirubicin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00322374).
- Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide: Complete Statistical AnalysisIndependent statistical analysis of Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00629343).
- Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase I Study of Intensity Modulated Radiation Therapy for Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study of Intensity Modulated Radiation Therapy for Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) Followed by Ipilimumab in Advanced Metastatic Melanoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) Followed by Ipilimumab in Advanced Metastatic Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase I Study of OPC-61815: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study of OPC-61815: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03510663).
- Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis: primary endpoint results, effect estimate with…
- Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP): Complete Statistical AnalysisIndependent statistical analysis of Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00356993).
- Phase I TH-302 Plus Gemcitabine Plus Nab-Paclitaxel in Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of Phase I TH-302 Plus Gemcitabine Plus Nab-Paclitaxel in Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02047500).
- Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Phase I, Open Label Dose Escalation Study to Evaluate Safety of iHIVARNA-01 in Chronically HIV-infected Patients: Complete Statistical AnalysisIndependent statistical analysis of Phase I, Open Label Dose Escalation Study to Evaluate Safety of iHIVARNA-01 in Chronically HIV-infected Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors: Complete Statistical AnalysisIndependent statistical analysis of Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Phase I/II Study of OPB-31121 in Patients With Progressive Hepatocellular Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Phase I/II Study of OPB-31121 in Patients With Progressive Hepatocellular Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase I/II Study of Pentostatin Combined With Tacrolimus and Mini-Methotrexate for GVHD Prevention After MUD BMT: Complete Statistical AnalysisIndependent statistical analysis of Phase I/II Study of Pentostatin Combined With Tacrolimus and Mini-Methotrexate for GVHD Prevention After MUD BMT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…