Trials that use: Interim analysis / alpha spending
New to this method? Read the tutorial →
11,819 results
- Study of Pembrolizumab Versus Docetaxel in Participants Previously Treated for Non-Small Cell Lung Cancer (MK-3475-033/KEYNOTE-033): Complete Statistical AnalysisIndependent statistical analysis of Study of Pembrolizumab Versus Docetaxel in Participants Previously Treated for Non-Small Cell Lung Cancer (MK-3475-033/KEYNOTE-033): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006): Complete Statistical AnalysisIndependent statistical analysis of Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006): primary endpoint results, effect estimate with confidence interval,…
- Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Pembrolizumab, Binimetinib, and Bevacizumab in Patients With Refractory Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy: Complete Statistical AnalysisIndependent statistical analysis of Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been…
- Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789): Complete Statistical AnalysisIndependent statistical analysis of Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung…
- Study of Pemetrexed and Bevacizumab in Patients With Head and Neck Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Pemetrexed and Bevacizumab in Patients With Head and Neck Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study: Complete Statistical AnalysisIndependent statistical analysis of Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study: primary endpoint results, effect estimate…
- Study Of PF-00562271, Including Patients With Pancreatic, Head And Neck, Prostatic Neoplasms: Complete Statistical AnalysisIndependent statistical analysis of Study Of PF-00562271, Including Patients With Pancreatic, Head And Neck, Prostatic Neoplasms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies: Complete Statistical AnalysisIndependent statistical analysis of Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies: primary endpoint results, effect estimate with confidence…
- STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT: Complete Statistical AnalysisIndependent statistical analysis of STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- STUDY OF PF-07321332 IN HEALTHY PARTICIPANTS: Complete Statistical AnalysisIndependent statistical analysis of STUDY OF PF-07321332 IN HEALTHY PARTICIPANTS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04756531).
- Study of Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair: Complete Statistical AnalysisIndependent statistical analysis of Study of Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined Dyslipidemia: Complete Statistical AnalysisIndependent statistical analysis of Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined Dyslipidemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas: Complete Statistical AnalysisIndependent statistical analysis of Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia: Complete Statistical AnalysisIndependent statistical analysis of Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment: Complete Statistical AnalysisIndependent statistical analysis of Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study of Prasugrel in Korean Healthy Male Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Study of Prasugrel in Korean Healthy Male Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01591317).
- Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy: Complete Statistical AnalysisIndependent statistical analysis of Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study of Produce Prescription Programs in Adults With Overweight or Obesity Experiencing Nutrition Insecurity: Complete Statistical AnalysisIndependent statistical analysis of Study of Produce Prescription Programs in Adults With Overweight or Obesity Experiencing Nutrition Insecurity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study of Progression to Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Incidence/Management and Treatment: Complete Statistical AnalysisIndependent statistical analysis of Study of Progression to Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Incidence/Management and Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults: Complete Statistical AnalysisIndependent statistical analysis of Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines in a Simulated Post-Exposure Regimen in Adults: primary endpoint results, effect estimate with confidence interval, sample-size…
- Study of Quadrivalent Influenza Vaccine Among Children: Complete Statistical AnalysisIndependent statistical analysis of Study of Quadrivalent Influenza Vaccine Among Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01240746).
- Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive…
- Study of Ramucirumab in Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Ramucirumab in Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00721162).
- Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD): Complete Statistical AnalysisIndependent statistical analysis of Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older: Complete Statistical AnalysisIndependent statistical analysis of Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older: primary endpoint…
- Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids: Complete Statistical AnalysisIndependent statistical analysis of Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study of Repeat Intranodal Injection of Memgen’s Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): Complete Statistical AnalysisIndependent statistical analysis of Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): primary endpoint results, effect estimate with confidence interval, sample-size…
- Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting: Complete Statistical AnalysisIndependent statistical analysis of Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting: primary endpoint results, effect estimate with confidence…
- Study of Rivoglitazone in Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of Study of Rivoglitazone in Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00484198).
- Study of Romiplostim for Chemotherapy Induced Thrombocytopenia: Complete Statistical AnalysisIndependent statistical analysis of Study of Romiplostim for Chemotherapy Induced Thrombocytopenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02052882).
- Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With Anemia: Complete Statistical AnalysisIndependent statistical analysis of Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With Anemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of RSVpreF Vaccination and RSV Challenge in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of Study of RSVpreF Vaccination and RSV Challenge in Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04785612).
- Study of Ruxolitinib in Colorectal Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Study of Ruxolitinib in Colorectal Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02119676).
- Study of Ruxolitinib in Pancreatic Cancer Patients (Janus 1): Complete Statistical AnalysisIndependent statistical analysis of Study of Ruxolitinib in Pancreatic Cancer Patients (Janus 1): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02117479).
- Study of Safety and Efficacy of an Oral Contraceptive: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Efficacy of an Oral Contraceptive: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00932321).
- Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016): Complete Statistical AnalysisIndependent statistical analysis of Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042): Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer: primary endpoint results, effect estimate with confidence…
- Study of Safety and Immunogenicity of Fluzone® in Healthy Children: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Immunogenicity of Fluzone® in Healthy Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00831675).
- Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study of Safety of Foradil in Patients With Persistent Asthma: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety of Foradil in Patients With Persistent Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01845025).
- Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis: Complete Statistical AnalysisIndependent statistical analysis of Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM: Complete Statistical AnalysisIndependent statistical analysis of Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation: Complete Statistical AnalysisIndependent statistical analysis of Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260): Complete Statistical AnalysisIndependent statistical analysis of Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260): primary endpoint results, effect estimate with confidence interval, sample-size planning…