Trials that use: Interim analysis / alpha spending
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11,819 results
- Study of the Safety and Tolerability of AXA1125 and AXA1957 in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD): Complete Statistical AnalysisIndependent statistical analysis of Study of the Safety and Tolerability of AXA1125 and AXA1957 in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders: Complete Statistical AnalysisIndependent statistical analysis of Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study of the Safety, Tolerability and Efficacy of BTX 1204 in Patients With Moderate Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of Study of the Safety, Tolerability and Efficacy of BTX 1204 in Patients With Moderate Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study of the Safety, Tolerability, and Pharmacokinetics of Once Weekly Zicronapine in Patients With Schizophrenia: Complete Statistical AnalysisIndependent statistical analysis of Study of the Safety, Tolerability, and Pharmacokinetics of Once Weekly Zicronapine in Patients With Schizophrenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Pembrolizumab (MK-3475) in Chinese Participants With Non-Small-Cell Lung Cancer (MK-3475-032/KEYNOTE-032): Complete Statistical AnalysisIndependent statistical analysis of Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Pembrolizumab (MK-3475) in Chinese Participants With Non-Small-Cell Lung Cancer (MK-3475-032/KEYNOTE-032): primary endpoint results, effect estimate with confidence interval, sample-size…
- Study of the Sensitivity of Manual vs Electric Aspiration to Detect Completed Early Abortion: Complete Statistical AnalysisIndependent statistical analysis of Study of the Sensitivity of Manual vs Electric Aspiration to Detect Completed Early Abortion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study of Three Different Schedules of Low-Dose Decitabine in Myelodysplastic Syndrome (MDS): Complete Statistical AnalysisIndependent statistical analysis of Study of Three Different Schedules of Low-Dose Decitabine in Myelodysplastic Syndrome (MDS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study of Tideglusib in Adolescent and Adult Patients With Myotonic Dystrophy: Complete Statistical AnalysisIndependent statistical analysis of Study of Tideglusib in Adolescent and Adult Patients With Myotonic Dystrophy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of Tislelizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Tislelizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of TJ003234 (Anti-GM-CSF Monoclonal Antibody) in Subjects With Severe Coronavirus Disease 2019 (COVID-19): Complete Statistical AnalysisIndependent statistical analysis of Study of TJ003234 (Anti-GM-CSF Monoclonal Antibody) in Subjects With Severe Coronavirus Disease 2019 (COVID-19): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture: Complete Statistical AnalysisIndependent statistical analysis of Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Study of Vaniprevir Plus PegIntron®/Ribavirin in Japanese Participants With Chronic Hepatitis C Who Relapsed After Treatment (MK-7009-044): Complete Statistical AnalysisIndependent statistical analysis of Study of Vaniprevir Plus PegIntron®/Ribavirin in Japanese Participants With Chronic Hepatitis C Who Relapsed After Treatment (MK-7009-044): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of Vitamin D in Untreated Metastatic Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study of Vitamin D in Untreated Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01516216).
- Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults: Complete Statistical AnalysisIndependent statistical analysis of Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO): Complete Statistical AnalysisIndependent statistical analysis of Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO): primary endpoint results, effect estimate with confidence interval,…
- Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN): Complete Statistical AnalysisIndependent statistical analysis of Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study of Vorinostat (MK0683), an Histone Deacetylase (HDAC) Inhibitor in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (MK-0683-095): Complete Statistical AnalysisIndependent statistical analysis of Study of Vorinostat (MK0683), an Histone Deacetylase (HDAC) Inhibitor in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (MK-0683-095): primary endpoint results, effect estimate with…
- Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study of VVN001 Ophthalmic Solution in Dry Eye Disease: Complete Statistical AnalysisIndependent statistical analysis of Study of VVN001 Ophthalmic Solution in Dry Eye Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04556838).
- Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy: Complete Statistical AnalysisIndependent statistical analysis of Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy: primary endpoint…
- Study of Zemplar iv in Patients With End Stage Chronic Kidney Disease, Undergoing Haemodialysis: Complete Statistical AnalysisIndependent statistical analysis of Study of Zemplar iv in Patients With End Stage Chronic Kidney Disease, Undergoing Haemodialysis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study on a MenACYW Conjugate Vaccine Administered as a Single Dose in Participants Aged 12 Months and Older in Vietnam: Complete Statistical AnalysisIndependent statistical analysis of Study on a MenACYW Conjugate Vaccine Administered as a Single Dose in Participants Aged 12 Months and Older in Vietnam: primary endpoint results, effect estimate with confidence interval,…
- Study on an Investigational Yellow Fever Vaccine Compared With Stamaril in Adults in Europe and Asia: Complete Statistical AnalysisIndependent statistical analysis of Study on an Investigational Yellow Fever Vaccine Compared With Stamaril in Adults in Europe and Asia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study on BI 54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Low Dose Inhaled Corticosteroid (ICS): Complete Statistical AnalysisIndependent statistical analysis of Study on BI 54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Low Dose Inhaled Corticosteroid (ICS): primary endpoint results, effect…
- Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort): Complete Statistical AnalysisIndependent statistical analysis of Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study on OsseoSpeed™ TX Implants in a Chinese Population: Complete Statistical AnalysisIndependent statistical analysis of Study on OsseoSpeed™ TX Implants in a Chinese Population: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01346683).
- Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI): Complete Statistical AnalysisIndependent statistical analysis of Study on Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Percutaneous Coronary Intervention (PCI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy: Complete Statistical AnalysisIndependent statistical analysis of Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy: primary endpoint results, effect estimate with confidence interval,…
- Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation: Complete Statistical AnalysisIndependent statistical analysis of Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery: Complete Statistical AnalysisIndependent statistical analysis of Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study STF115288, a Clinical Confirmation Study of GI148512 in the Treatment of Acne Vulgaris in Japanese Subjects: Complete Statistical AnalysisIndependent statistical analysis of Study STF115288, a Clinical Confirmation Study of GI148512 in the Treatment of Acne Vulgaris in Japanese Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel: Complete Statistical AnalysisIndependent statistical analysis of Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants: primary endpoint results, effect…
- Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of…
- Study to Assess Brincidofovir Treatment of Serious Diseases or Conditions Caused by Double-stranded DNA Viruses: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Brincidofovir Treatment of Serious Diseases or Conditions Caused by Double-stranded DNA Viruses: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle…
- Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD): Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Assess if ABP 798 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis (RA) Compared to Rituximab: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess if ABP 798 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis (RA) Compared to Rituximab: primary endpoint results, effect estimate with confidence…
- Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen: primary endpoint results, effect estimate with confidence interval,…
- Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected Persons: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected Persons: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren’s Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment…
- Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]: primary endpoint results, effect estimate with…
- Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma: primary endpoint results, effect estimate with confidence…
- Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea: primary endpoint results, effect estimate with confidence interval, sample-size planning…