Trials that use: Interim analysis / alpha spending
New to this method? Read the tutorial →
11,819 results
- Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer: primary endpoint results, effect estimate with confidence…
- Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Effectiveness and Safety of FLECTOR Patch for Treatment of Acute Back Strain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients: primary endpoint results, effect estimate…
- Study to Assess the Efficacy and Safety of CJM112 in Patients With Inadequately Controlled Severe Asthma: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of CJM112 in Patients With Inadequately Controlled Severe Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess the Efficacy and Safety of NTRA-2112 on Intestinal Malabsorption in Preterm Infants: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of NTRA-2112 on Intestinal Malabsorption in Preterm Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD: primary endpoint results, effect estimate with confidence interval,…
- Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 in Subjects With Moderate to Very Severe COPD (Ethos): Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 in Subjects With Moderate to Very Severe COPD (Ethos): primary endpoint results, effect estimate…
- Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax: primary endpoint results,…
- Study to Assess the Efficacy and Safety of Umbralisib in Participants With Non-Follicular Indolent Non-Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy and Safety of Umbralisib in Participants With Non-Follicular Indolent Non-Hodgkin's Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain Injury: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain Injury: primary…
- Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Taiwanese Adults 65 Years of Age and Older: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Taiwanese Adults…
- Study to Assess the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals’ Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) When Co-administered With GSK Biologicals’ Diphtheria, Tetanus and Pertussis Vaccine (Boostrix®) in Adults Aged 50 Years and Older: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) When Co-administered With GSK Biologicals' Diphtheria, Tetanus and Pertussis Vaccine (Boostrix®)…
- Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to
- Study to Assess the Safety and Effectiveness of the Penumbra System: Complete Statistical AnalysisIndependent statistical analysis of Study to Assess the Safety and Effectiveness of the Penumbra System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study to Characterize the Pharmacokinetics of a Single Dose of SC Abatacept 125 mg Using the BD Autoinjector or the Prefilled Syringe: Complete Statistical AnalysisIndependent statistical analysis of Study to Characterize the Pharmacokinetics of a Single Dose of SC Abatacept 125 mg Using the BD Autoinjector or the Prefilled Syringe: primary endpoint results, effect estimate with…
- Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD: primary endpoint results, effect estimate with confidence interval, sample-size…
- Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA: primary endpoint results, effect estimate with confidence interval, sample-size…
- Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip: primary endpoint results, effect estimate with confidence…
- Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin): Complete Statistical AnalysisIndependent statistical analysis of Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD): Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD): primary endpoint…
- Study to Compare the Effect of Ipilimumab Retreatment With That of Chemotherapy in Advanced Melanoma: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Effect of Ipilimumab Retreatment With That of Chemotherapy in Advanced Melanoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly Patients: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol Levels: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol Levels: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers: primary endpoint results, effect estimate with confidence interval,…
- Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS Glargine (G), United States (US)-Lantus®, and European Union (EU)-Lantus®: Complete Statistical AnalysisIndependent statistical analysis of Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS Glargine (G), United States (US)-Lantus®, and European Union (EU)-Lantus®: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(A), US-NovoLog®, and EU-NovoRapid®: Complete Statistical AnalysisIndependent statistical analysis of Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(A), US-NovoLog®, and EU-NovoRapid®: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA: Complete Statistical AnalysisIndependent statistical analysis of Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA: primary endpoint results, effect estimate with…
- Study to Determine Effects of Vesicare on Return to Continence Post – Radical Prostatectomy (Part II): Complete Statistical AnalysisIndependent statistical analysis of Study to Determine Effects of Vesicare on Return to Continence Post - Radical Prostatectomy (Part II): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test): Complete Statistical AnalysisIndependent statistical analysis of Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test): Complete Statistical AnalysisIndependent statistical analysis of Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test): primary endpoint results, effect estimate with confidence interval,…
- Study to Determine the Maximum Tolerated Dose of the PARP Inhibitor CEP-9722 in Participants With Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Study to Determine the Maximum Tolerated Dose of the PARP Inhibitor CEP-9722 in Participants With Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information: Complete Statistical AnalysisIndependent statistical analysis of Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332: Complete Statistical AnalysisIndependent statistical analysis of Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In Patients With Post-Tooth Extraction Pain: Complete Statistical AnalysisIndependent statistical analysis of Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In Patients With Post-Tooth Extraction Pain: primary endpoint results, effect estimate with confidence interval, sample-size…
- Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL): Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study to Evaluate Efficacy, Safety and Immunogenicity of GSK Biologicals’ Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 50 Years and Older: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Efficacy, Safety and Immunogenicity of GSK Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 50 Years and Older: primary endpoint results, effect estimate with…
- Study to Evaluate Efficacy, Safety, and Immunogenicity of GlaxoSmithKline (GSK) Biologicals’ Herpes Zoster Vaccine GSK1437173A: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Efficacy, Safety, and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Vaccine GSK1437173A: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals’ Quadrivalent Influenza Vaccine GSK2282512A When Administered to Children From 6 to 35 Months of Age: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine GSK2282512A When Administered to Children From 6 to 35 Months of Age: primary endpoint results,…
- Study to Evaluate Immunogenicity and Safety of GSK Biologicals’ Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2…
- Study to Evaluate Intravenous and Oral Steroids for Multiple Sclerosis Attacks: Complete Statistical AnalysisIndependent statistical analysis of Study to Evaluate Intravenous and Oral Steroids for Multiple Sclerosis Attacks: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…