Trials that use: Interim analysis / alpha spending
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4,594 results
- Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment: Complete Statistical AnalysisIndependent statistical analysis of Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02317783).
- An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect: Complete Statistical AnalysisIndependent statistical analysis of An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- An Automated Virtual Reality Intervention to Enhance Firearm Safety Counseling in Pediatrics: Complete Statistical AnalysisIndependent statistical analysis of An Automated Virtual Reality Intervention to Enhance Firearm Safety Counseling in Pediatrics: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis: Complete Statistical AnalysisIndependent statistical analysis of An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy: Complete Statistical AnalysisIndependent statistical analysis of An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy: primary endpoint results, effect estimate with confidence interval, sample-size…
- An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma: primary endpoint results, effect estimate with…
- An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections: primary endpoint results, effect estimate with confidence interval,…
- An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung:…
- An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- An Efficacy and Safety Study of Sonazoid™ and SonoVue® in Participants With Focal Liver Lesions, Undergoing Pre- and Post-Contrast Ultrasound Imaging: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Sonazoid™ and SonoVue® in Participants With Focal Liver Lesions, Undergoing Pre- and Post-Contrast Ultrasound Imaging: primary endpoint results, effect estimate with confidence…
- An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics: primary endpoint results, effect estimate with confidence interval,…
- An Efficacy Study of Chlorhexidine Mouthwashes: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy Study of Chlorhexidine Mouthwashes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01751178).
- An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis: Complete Statistical AnalysisIndependent statistical analysis of An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge: Complete Statistical AnalysisIndependent statistical analysis of An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- An Evaluation of the Energy Expenditure From Wii Fit Games: Complete Statistical AnalysisIndependent statistical analysis of An Evaluation of the Energy Expenditure From Wii Fit Games: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01561716).
- An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.: Complete Statistical AnalysisIndependent statistical analysis of An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size…
- An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024): Complete Statistical AnalysisIndependent statistical analysis of An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene: Complete Statistical AnalysisIndependent statistical analysis of An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma…
- An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS: Complete Statistical AnalysisIndependent statistical analysis of An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS: primary endpoint results, effect estimate with confidence…
- An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR: Complete Statistical AnalysisIndependent statistical analysis of An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma: Complete Statistical AnalysisIndependent statistical analysis of An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma: primary endpoint results, effect…
- An Open Label Study for Participants With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Study for Participants With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01215942).
- An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Open Label Trial of Bupropion and Naltrexone for Binge Drinking: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Trial of Bupropion and Naltrexone for Binge Drinking: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects: Complete Statistical AnalysisIndependent statistical analysis of An Open-label Extension Study to Evaluate the Safety and Tolerability of Perampanel (E2007) Administered as an Adjunctive Therapy in Epilepsy Subjects: primary endpoint results, effect estimate with confidence…
- An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD): Complete Statistical AnalysisIndependent statistical analysis of An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD): primary endpoint results, effect estimate with…
- An Open-Label Phase II Study of the Combination of GSK2118436 and GSK1120212 in Patients With Metastatic Melanoma Which is Refractory or Resistant to BRAF Inhibitor: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Phase II Study of the Combination of GSK2118436 and GSK1120212 in Patients With Metastatic Melanoma Which is Refractory or Resistant to BRAF Inhibitor: primary endpoint results,…
- An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites: Complete Statistical AnalysisIndependent statistical analysis of An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites: primary endpoint results, effect estimate with confidence…
- An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area: Complete Statistical AnalysisIndependent statistical analysis of An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5): Complete Statistical AnalysisIndependent statistical analysis of An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5): primary endpoint results, effect estimate with confidence interval, sample-size…
- An Open-label, Multi-center Study Evaluating the Validity, Reliability, and Responsiveness of a New Female-specific Angina Questionnaire in Women With Chronic Angina Treated With Ranolazine Extended-release Tablets (CVT 3041): Complete Statistical AnalysisIndependent statistical analysis of An Open-label, Multi-center Study Evaluating the Validity, Reliability, and Responsiveness of a New Female-specific Angina Questionnaire in Women With Chronic Angina Treated With Ranolazine Extended-release Tablets (CVT 3041):…
- An Open-Label, Proof-of-Concept Study of Ixekizumab in the Treatment of Pyoderma Gangrenosum: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label, Proof-of-Concept Study of Ixekizumab in the Treatment of Pyoderma Gangrenosum: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator’s Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026): Complete Statistical AnalysisIndependent statistical analysis of An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026): primary…
- An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia: Complete Statistical AnalysisIndependent statistical analysis of An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge): Complete Statistical AnalysisIndependent statistical analysis of An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Analysis of the Effect of Antimicrobial Soap on Bacterial Survival: Complete Statistical AnalysisIndependent statistical analysis of Analysis of the Effect of Antimicrobial Soap on Bacterial Survival: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02012348).
- Analytical Treatment Interruption (ATI) to Assess the Immune System’s Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study: Complete Statistical AnalysisIndependent statistical analysis of Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study: primary endpoint results,…
- Ancillary Study of the Lessening Incontinence With Low-impact Activity Study: Complete Statistical AnalysisIndependent statistical analysis of Ancillary Study of the Lessening Incontinence With Low-impact Activity Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04776720).
- Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women: Complete Statistical AnalysisIndependent statistical analysis of Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1: Complete Statistical AnalysisIndependent statistical analysis of Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02574910).