Trials that use: Interim analysis / alpha spending
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3,081 results
- A Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastatic Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastatic Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic Malignancy: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic Malignancy: primary endpoint results, effect estimate with…
- A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib:…
- A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC): Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Phase II Study of Intravenous Azacitidine Alone in Patients With Myelodysplastic Syndromes: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Intravenous Azacitidine Alone in Patients With Myelodysplastic Syndromes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Phase II Study of Paclitaxel and Carboplatin in Patients With an Elevated-Risk Cancer of the Uterus: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Paclitaxel and Carboplatin in Patients With an Elevated-Risk Cancer of the Uterus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Phase II Study on Immunogenicity and Safety of MVA-BN® (IMVAMUNE™) Smallpox Vaccine in Subjects With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study on Immunogenicity and Safety of MVA-BN® (IMVAMUNE™) Smallpox Vaccine in Subjects With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma: primary endpoint results, effect estimate with…
- A Phase II Trial of Alemtuzumab and Rituximab in Patients With Previously Untreated CLL: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Alemtuzumab and Rituximab in Patients With Previously Untreated CLL: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodgkin's Lymphoma: primary endpoint results, effect estimate with confidence interval,…
- A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Phase II Trial of Regadenoson in Sickle Cell Anemia: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Regadenoson in Sickle Cell Anemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01788631).
- A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Phase II, Repeat Dose, Proof of Mechanism Study of Losmapimod to Reduce Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS): Complete Statistical AnalysisIndependent statistical analysis of A Phase II, Repeat Dose, Proof of Mechanism Study of Losmapimod to Reduce Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS): primary endpoint results, effect estimate with confidence…
- A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA): Complete Statistical AnalysisIndependent statistical analysis of A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA): primary endpoint results, effect estimate with confidence interval, sample-size…
- A Phase III Study of TMC435 in Treatment-naive, Genotype 1, Hepatitis C-infected Patients: Complete Statistical AnalysisIndependent statistical analysis of A Phase III Study of TMC435 in Treatment-naive, Genotype 1, Hepatitis C-infected Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Phase III Study to Assess the Lot-to-lot Consistency of GSK’s Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone or Co-administered With GSK’s Influenza D-QIV Vaccine in Healthy Non-pregnant Women.: Complete Statistical AnalysisIndependent statistical analysis of A Phase III Study to Assess the Lot-to-lot Consistency of GSK's Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone…
- A Phase III Trial For Patients With Metastatic Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Phase III Trial For Patients With Metastatic Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00191152).
- A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial: Complete Statistical AnalysisIndependent statistical analysis of A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Pilot Feasibility Study of Mindfulness-Oriented Recovery Enhancement With Pregnant Women With Opioid Use Disorder: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Feasibility Study of Mindfulness-Oriented Recovery Enhancement With Pregnant Women With Opioid Use Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Pilot Intervention to Improve Coping With Discrimination and Adherence Among HIV-Positive Latino MSM: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Intervention to Improve Coping With Discrimination and Adherence Among HIV-Positive Latino MSM: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Pilot Study Assessing the Effect of Lymphaticovenous Micro-Anastomosis in the Treatment of Postmastectomy Lymphedema: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study Assessing the Effect of Lymphaticovenous Micro-Anastomosis in the Treatment of Postmastectomy Lymphedema: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Pilot Study of a Non-Invasive Neuromodulation Device for Treatment of Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study of a Non-Invasive Neuromodulation Device for Treatment of Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Pilot Study on Diurnal Variation: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study on Diurnal Variation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01806051).
- A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Pilot Trial Using BR55 Ultrasound Contrast Agent in the Assessment of Prostate Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Trial Using BR55 Ultrasound Contrast Agent in the Assessment of Prostate Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Placebo Controlled Trial of Dalfampridine ER for Ambulatory Activity in People With Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Placebo Controlled Trial of Dalfampridine ER for Ambulatory Activity in People With Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine: Complete Statistical AnalysisIndependent statistical analysis of A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093: Complete Statistical AnalysisIndependent statistical analysis of A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Post-Market Clinical Evaluation of the ReUnion TSA System: Complete Statistical AnalysisIndependent statistical analysis of A Post-Market Clinical Evaluation of the ReUnion TSA System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03858517).
- A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors: Complete Statistical AnalysisIndependent statistical analysis of A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves’ Disease: Complete Statistical AnalysisIndependent statistical analysis of A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Proof-of-principle Study of HBO-SRS for Brain Metastases: Complete Statistical AnalysisIndependent statistical analysis of A Proof-of-principle Study of HBO-SRS for Brain Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01850563).
- A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Prospective, Epidemiological Study to Assess the Disease Burden of Respiratory Syncytial Virus Associated, Suspected Lower Respiratory Tract Infections in Newborns, From 0 to 2 Years of Age and Risk of Development of Wheeze and Asthma From 0 to 6 Years of Age: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Epidemiological Study to Assess the Disease Burden of Respiratory Syncytial Virus Associated, Suspected Lower Respiratory Tract Infections in Newborns, From 0 to 2 Years of Age…
- A Prospective, Multi-Center Evaluation of Corneal Flap Creation Using Cheetah Femtosecond Laser System and Cheetah Patient Interface: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Multi-Center Evaluation of Corneal Flap Creation Using Cheetah Femtosecond Laser System and Cheetah Patient Interface: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Prospective, Open-label Study of [68Ga]Ga-DOTA-TATE in Patients With Neuroendocrine Neoplasms (NENs) and Healthy Volunteers in Japan: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Open-label Study of [68Ga]Ga-DOTA-TATE in Patients With Neuroendocrine Neoplasms (NENs) and Healthy Volunteers in Japan: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes: Complete Statistical AnalysisIndependent statistical analysis of A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Randomized Clinical Trial on Hemoglobin Dose and Patient Matching: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Clinical Trial on Hemoglobin Dose and Patient Matching: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01328262).
- A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study): Complete Statistical AnalysisIndependent statistical analysis of A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Randomized Controlled Trial of In-Home Tele-Behavioral Health Care Utilizing Behavioral Activation for Depression: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Controlled Trial of In-Home Tele-Behavioral Health Care Utilizing Behavioral Activation for Depression: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Randomized Phase 2 Pharmacokinetic Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Phase 2 Pharmacokinetic Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck: primary endpoint…
- A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN): Complete Statistical AnalysisIndependent statistical analysis of A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…