Trials that use: Interim analysis / alpha spending
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11,819 results
- Efficacy and Safety of Elbasvir (MK-8742) + Grazoprevir (MK-5172) in Treatment-Naïve/Treatment-Experienced (TN/TE) French Participants With Hepatitis C Virus (HCV) Genotype 4 (GT4) Infection (MK-5172-096): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Elbasvir (MK-8742) + Grazoprevir (MK-5172) in Treatment-Naïve/Treatment-Experienced (TN/TE) French Participants With Hepatitis C Virus (HCV) Genotype 4 (GT4) Infection (MK-5172-096): primary endpoint results, effect…
- Efficacy and Safety of Elpipodect (MK-8189) in Participants With an Acute Episode of Schizophrenia (MK-8189-008): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Elpipodect (MK-8189) in Participants With an Acute Episode of Schizophrenia (MK-8189-008): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients: primary endpoint results, effect…
- Efficacy and Safety of Empagliflozin (BI 10773) in Patients With Type 2 Diabetes and Renal Impairment: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Empagliflozin (BI 10773) in Patients With Type 2 Diabetes and Renal Impairment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Safety of Empagliflozin (BI 10773) Versus Placebo and Sitagliptin Over 24 Weeks in Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Empagliflozin (BI 10773) Versus Placebo and Sitagliptin Over 24 Weeks in Patients With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval,…
- Efficacy and Safety of Esflurbiprofen Hydrogel Patch in the Treatment of Local Acute Pain: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Esflurbiprofen Hydrogel Patch in the Treatment of Local Acute Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Eslicarbazepine Acetate as Therapy in Subjects With Fibromyalgia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Eslicarbazepine Acetate as Therapy in Subjects With Fibromyalgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059): primary endpoint results, effect estimate with confidence interval, sample-size…
- Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062): primary endpoint results, effect estimate…
- Efficacy and Safety of Etrasimod (APD334) in Inflammatory Bowel Disease Patients With Active Skin Extra-intestinal Manifestations: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Etrasimod (APD334) in Inflammatory Bowel Disease Patients With Active Skin Extra-intestinal Manifestations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Famciclovir 1-day Treatment Compared to 3-day Treatment With Valacyclovir in Adults With Recurrent Genital Herpes: primary endpoint results, effect estimate with confidence interval, sample-size…
- Efficacy and Safety of Farletuzumab (MORAb-003) in Combination With Carboplatin and Taxane in Participants With Platinum-sensitive Ovarian Cancer in First Relapse: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Farletuzumab (MORAb-003) in Combination With Carboplatin and Taxane in Participants With Platinum-sensitive Ovarian Cancer in First Relapse: primary endpoint results, effect estimate with confidence…
- Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Finalgon® Cream Multiple Doses in Acute Low Back Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Four Doses of Glycopyrronium Bromide (NVA237) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), in Comparison to an Active Comparator Tiotropium: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Four Doses of Glycopyrronium Bromide (NVA237) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), in Comparison to an Active Comparator Tiotropium: primary endpoint…
- Efficacy and Safety of G001 in Patients With Osteoarthritis (OA) of the Knee: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of G001 in Patients With Osteoarthritis (OA) of the Knee: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Safety of Grass Sublingual Tablet in Children and Adolescents (P05239 AM3)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Grass Sublingual Tablet in Children and Adolescents (P05239 AM3)(COMPLETED): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Grazoprevir (+) Uprifosbuvir (+) Ruzasvir (MK-3682B) (MK-5172 + MK-3682 + MK-8408) Fixed Dose Combination in Chronic HCV Participants Failing Prior Antiviral Treatment (MK-3682-021): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Grazoprevir (+) Uprifosbuvir (+) Ruzasvir (MK-3682B) (MK-5172 + MK-3682 + MK-8408) Fixed Dose Combination in Chronic HCV Participants Failing Prior Antiviral Treatment (MK-3682-021): primary…
- Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Efficacy and Safety of IBI-10090 in Ocular Surgery Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of IBI-10090 in Ocular Surgery Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01606735).
- Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of Indacaterol Acetate Delivered Via the Concept1 Inhalation Device in Children Greater or Equal to 6 and Less Than 12 Years of Age With Asthma: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Indacaterol Acetate Delivered Via the Concept1 Inhalation Device in Children Greater or Equal to 6 and Less Than 12 Years of Age With Asthma:…
- Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Using Salmeterol as Active Control: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Using Salmeterol as Active Control: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients: primary endpoint results, effect estimate with confidence…
- Efficacy and Safety of Intravenous Ferric Carboxymaltose in Pediatric Patients With Iron Deficiency Anemia and Unsatisfactory Response Oral Iron Under Study Protocol 1VIT17044: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Intravenous Ferric Carboxymaltose in Pediatric Patients With Iron Deficiency Anemia and Unsatisfactory Response Oral Iron Under Study Protocol 1VIT17044: primary endpoint results, effect estimate…
- Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Intravenous Phenobarbital in Neonatal Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04320940).
- Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Safety of Itolizumab in COVID-19 Complications: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Itolizumab in COVID-19 Complications: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04475588).
- Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004): primary endpoint results, effect estimate with confidence interval,…
- Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis Vulgaris: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis Vulgaris: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Licefreee Spray Against Nix 1% Permethrin: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Licefreee Spray Against Nix 1% Permethrin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01514513).
- Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of Metoclopramide Nasal Spray Solution in Diabetic Patients With Gastroparesis: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Metoclopramide Nasal Spray Solution in Diabetic Patients With Gastroparesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic Urticaria: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic Urticaria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…