Trials that use: Non-inferiority trial design
New to this method? Read the tutorial →
637 results
- A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77): Complete Statistical AnalysisIndependent statistical analysis of A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77): primary endpoint results,…
- A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: primary…
- A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01390441).
- A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Tirzepatide (LY3298176) in Healthy Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tirzepatide (LY3298176) in Healthy Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03375463).
- A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer: primary endpoint results, effect estimate with confidence interval,…
- A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): Complete Statistical AnalysisIndependent statistical analysis of A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002): Complete Statistical AnalysisIndependent statistical analysis of A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002): primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or…
- A Study on the Immune Response, Safety and the Occurrence of Respiratory Syncytial Virus (RSV)-Associated Respiratory Tract Illness After Administration of RSV OA Vaccine in Adults 60 Years and Older: Complete Statistical AnalysisIndependent statistical analysis of A Study on the Immune Response, Safety and the Occurrence of Respiratory Syncytial Virus (RSV)-Associated Respiratory Tract Illness After Administration of RSV OA Vaccine in Adults 60 Years…
- A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study to Assess the Safety and Efficacy of a Daily Disposable Contact Lens: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of a Daily Disposable Contact Lens: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study to Compare SB16 (Proposed Denosumab Biosimilar) to Prolia® in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare SB16 (Proposed Denosumab Biosimilar) to Prolia® in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer: primary endpoint…
- A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg…
- A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive Surgery: primary endpoint results, effect estimate…
- A Study to Evaluate Effectiveness and Safety of ER OROS Paliperidone in Patients With Schizophrenia: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Effectiveness and Safety of ER OROS Paliperidone in Patients With Schizophrenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency: primary endpoint results, effect estimate with confidence interval,…
- A Study to Evaluate Safety, Tolerability, & Immunogenicity of Multiple Formulations of BNT162b2 Against COVID-19 in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Safety, Tolerability, & Immunogenicity of Multiple Formulations of BNT162b2 Against COVID-19 in Healthy Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg Salmeterol/500mcg Fluticasone Propionate (FP)): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg…
- A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects: primary endpoint results, effect estimate…
- A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High…
- A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic…
- A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults: primary endpoint results, effect estimate…
- A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 5 Through 17 Years of Age: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 5 Through 17 Years of Age: primary endpoint results, effect…
- A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 6 Months Through 59 Months of Age.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Immunogenicity and Safety of Seqirus Quadrivalent Influenza Vaccine (QIV) in a Pediatric Population 6 Months Through 59 Months of Age.: primary endpoint results,…
- A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009): primary endpoint results, effect estimate with confidence…
- A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Two Lots of V114 in Healthy Infants (V114-008): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Two Lots of V114 in Healthy Infants (V114-008): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): primary endpoint results, effect estimate with…
- A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as Reference (P05787): Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as…
- A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study to the Assess the Change in Condition and Adverse Events of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines: Complete Statistical AnalysisIndependent statistical analysis of A Study to the Assess the Change in Condition and Adverse Events of OnabotulinumtoxinA X Injection in Adult Participants With Glabellar Lines: primary endpoint results, effect estimate with…
- A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus…
- A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable…
- A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…