Cardiovascular Clinical Trials

Statistical methods in cardiovascular trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All cardiovascular trials

672 results

• 306A/306BIndependent statistical analysis of A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 225NCT01176240
• 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension: Complete Statistical AnalysisIndependent statistical analysis of 6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 327NCT02140060
• 8-week Randomized, Open-label Study to Evaluate Food Effect on Efficacy and Safety of Oral Aliskiren 300 mg in Patients With Hypertension: Complete Statistical AnalysisIndependent statistical analysis of 8-week Randomized, Open-label Study to Evaluate Food Effect on Efficacy and Safety of Oral Aliskiren 300 mg in Patients With Hypertension: primary endpoint results, effect estimate with confidence…Phase 4Results postedn = 589NCT01570686
• A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 5NCT00283933
• A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 45NCT00660309
• A Clinical Trial to Evaluate the HeartWare MVAD® System (MVAdvantage): Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial to Evaluate the HeartWare MVAD® System (MVAdvantage): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01831544).Phase NAResults postedn = 11NCT01831544
• A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04134845).Phase 2/3Results postedn = 68NCT04134845
• A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters: Complete Statistical AnalysisIndependent statistical analysis of A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 94NCT01196533
• A Comparative Study Between Amlodipine 10mg And 5mg With Hypertension For Whom 5mg Is Insufficient: Complete Statistical AnalysisIndependent statistical analysis of A Comparative Study Between Amlodipine 10mg And 5mg With Hypertension For Whom 5mg Is Insufficient: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 305NCT00415623
• A Feasibility Study of the Cordis Neurovascular Self Expanding Stent System in Intracranial Arteries: Complete Statistical AnalysisIndependent statistical analysis of A Feasibility Study of the Cordis Neurovascular Self Expanding Stent System in Intracranial Arteries: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 20NCT00349908
• A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH): Complete Statistical AnalysisIndependent statistical analysis of A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02651675).Phase 1/2Results postedn = 9NCT02651675
• A Gene Transfer Therapy Study to Evaluate the Safety of SRP-9004 (Patidistrogene Bexoparvovec) in Participants With Limb-Girdle Muscular Dystrophy, Type 2D (LGMD2D): Complete Statistical AnalysisIndependent statistical analysis of A Gene Transfer Therapy Study to Evaluate the Safety of SRP-9004 (Patidistrogene Bexoparvovec) in Participants With Limb-Girdle Muscular Dystrophy, Type 2D (LGMD2D): primary endpoint results, effect estimate with…Phase 1/2Results postedn = 6NCT01976091
• A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 564NCT00667719
• A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease: Complete Statistical AnalysisIndependent statistical analysis of A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 346NCT03384966
• A Multi-centre Study Comparing the Effects of AZD2927 and Placebo on the Electrical Activity in the Heart in Patients: Complete Statistical AnalysisIndependent statistical analysis of A Multi-centre Study Comparing the Effects of AZD2927 and Placebo on the Electrical Activity in the Heart in Patients: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 20NCT01396226
• A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 790NCT03374891
• A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 28NCT01677624
• A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8150 (MK-8150-002): Complete Statistical AnalysisIndependent statistical analysis of A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-8150 (MK-8150-002): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 1Results postedn = 103NCT01656408
• A Novel Approach for Brain Stimulation in Severe Stroke: Complete Statistical AnalysisIndependent statistical analysis of A Novel Approach for Brain Stimulation in Severe Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03868410).Phase EARLY_1Results postedn = 16NCT03868410
• A Personalized Self-care Support Program for Primary Care Patients With Diabetic Foot Ulcer: Complete Statistical AnalysisIndependent statistical analysis of A Personalized Self-care Support Program for Primary Care Patients With Diabetic Foot Ulcer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 29NCT06540170
• A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood Pressure: Complete Statistical AnalysisIndependent statistical analysis of A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood Pressure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 38NCT01005290
• A Phase 2 Study of Lenalidomide to Evaluate the Efficacy in Japanese Patients With Newly Diagnosed Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2 Study of Lenalidomide to Evaluate the Efficacy in Japanese Patients With Newly Diagnosed Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 26NCT01698801
• A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 1,267NCT02108262
• A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 542NCT01413399
• A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors: Complete Statistical AnalysisIndependent statistical analysis of A Post-Market Clinical Follow Up Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 157NCT05130762
• A Prospective Trial of Ayurveda for Coronary Artery Disease: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Trial of Ayurveda for Coronary Artery Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02228343).Phase NAResults postedn = 22NCT02228343
• A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: primary endpoint results, effect…Phase NAResults postedn = 13NCT04577183
• A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke: Complete Statistical AnalysisIndependent statistical analysis of A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel…Phase NAResults postedn = 198NCT01584609
• A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension: primary endpoint results,…Phase 2Results postedn = 48NCT00853112
• A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 4Results postedn = 6NCT00140621
• A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 418NCT00696384
• A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.: Complete Statistical AnalysisIndependent statistical analysis of A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2/3Results postedn = 123NCT00327392
• A Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies of Zelboraf (Vemurafenib): Complete Statistical AnalysisIndependent statistical analysis of A Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies of Zelboraf (Vemurafenib): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase NAResults postedn = 662NCT01804140
• A Single Dose Study of MK-8266 (MK-8266-001): Complete Statistical AnalysisIndependent statistical analysis of A Single Dose Study of MK-8266 (MK-8266-001): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01025791).Phase 1Results postedn = 25NCT01025791
• A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®) in Patients Receiving High-Dose Melphalan Conditioning Followed by Autologous Stem Cell Transplantation for Multiple Myeloma and Non-Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®) in Patients Receiving High-Dose Melphalan Conditioning Followed by Autologous Stem Cell Transplantation for Multiple Myeloma and Non-Hodgkin Lymphoma: primary…Phase NAResults postedn = 114NCT02919670
• A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart: Complete Statistical AnalysisIndependent statistical analysis of A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had…Phase 4Results postedn = 4,614NCT02415400
• A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00384865).Phase 2Results postedn = 64NCT00384865
• A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum: Complete Statistical AnalysisIndependent statistical analysis of A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05569252).Phase 2Results postedn = 65NCT05569252
• A Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of A Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 610NCT01181167
• A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 30NCT03456856
• A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH): Complete Statistical AnalysisIndependent statistical analysis of A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 77NCT04206605
• A Study of Loco-Regional Liposomal Bupivacaine Injection: Complete Statistical AnalysisIndependent statistical analysis of A Study of Loco-Regional Liposomal Bupivacaine Injection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05992896).Phase 4Results postedn = 3NCT05992896
• A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia: primary endpoint…Phase 2Results postedn = 154NCT05355402
• A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 1Results postedn = 33NCT01999335
• A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.: Complete Statistical AnalysisIndependent statistical analysis of A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 135NCT00353522
• A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR): Complete Statistical AnalysisIndependent statistical analysis of A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 324NCT04576988
• A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): Complete Statistical AnalysisIndependent statistical analysis of A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 7NCT05543174
• A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 12NCT00648895
• A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 200NCT00303498
• A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 4Results postedn = 1,009NCT00862641

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