Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
965 results
- IDEALAn independent statistical analysis of the IDEAL trial comparing atorvastatin with simvastatin in patients with known coronary heart disease, including trial design, the primary time-to-event endpoint, planned statistical methodology, and interpretation.
- IDNTAn independent statistical analysis and educational interpretation of IDNT (NCT00021918), an ancillary study of serum total homocysteine and C-reactive protein in cardiovascular and related metabolic conditions.
- iFR-SWEDEHEARTIndependent statistical analysis of the randomized iFR-SWEDEHEART trial comparing iFR with FFR in stable angina or acute coronary syndrome, including trial design, the 12-month composite endpoint, planned statistical analysis, and interpretation.
- IHAIndependent statistical analysis of Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- IKEMAIndependent statistical analysis of Multinational Clinical Study Comparing Isatuximab, Carfilzomib And Dexamethasone To Carfilzomib And Dexamethasone In Relapse And/Or Refractory Multiple Myeloma Patients: primary endpoint results, effect estimate with confidence interval, sample-size…
- ILLUMINATEIndependent statistical analysis of the ILLUMINATE phase 3 trial of torcetrapib/atorvastatin versus atorvastatin in patients with coronary disease and diabetes mellitus, including trial design, the primary cardiovascular endpoint, planned time-to-event analysis, and…
- IMAGE-ACSIndependent statistical analysis of Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Imaging in MGUS, SMM and MM: Complete Statistical AnalysisIndependent statistical analysis of Imaging in MGUS, SMM and MM: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01237054).
- Impact of CardiolRxTM on Recurrent Pericarditis (MAvERIC-Pilot): Complete Statistical AnalysisIndependent statistical analysis of Impact of CardiolRxTM on Recurrent Pericarditis (MAvERIC-Pilot): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05494788).
- Impact of LDL-cholesterol Lowering on Platelet Activation: Complete Statistical AnalysisIndependent statistical analysis of Impact of LDL-cholesterol Lowering on Platelet Activation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03331666).
- Impact of Liraglutide 3.0 on Body Fat Distribution: Complete Statistical AnalysisIndependent statistical analysis of Impact of Liraglutide 3.0 on Body Fat Distribution: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03038620).
- Impact of Ramadan on Achieving Joint National Committee (JNC) 7 Treatment Goals in CV Risk Patients: Complete Statistical AnalysisIndependent statistical analysis of Impact of Ramadan on Achieving Joint National Committee (JNC) 7 Treatment Goals in CV Risk Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Implementing HEARTS in Guatemala: Complete Statistical AnalysisIndependent statistical analysis of Implementing HEARTS in Guatemala: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06080451).
- IMPROVEIndependent statistical analysis of Immediate Management of the Patient With Rupture : Open Versus Endovascular Repair: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Improve SCA Bridge Study: Complete Statistical AnalysisIndependent statistical analysis of Improve SCA Bridge Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03715790).
- Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations: Complete Statistical AnalysisIndependent statistical analysis of Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01651208).
- IMPULSE: A Safety and Feasibility Study of the IOWA Approach Endocardial Ablation System to Treat Atrial Fibrillation: Complete Statistical AnalysisIndependent statistical analysis of IMPULSE: A Safety and Feasibility Study of the IOWA Approach Endocardial Ablation System to Treat Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Inflammation and Coronary Endothelial Function: Complete Statistical AnalysisIndependent statistical analysis of Inflammation and Coronary Endothelial Function: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02366091).
- Inflammation and Vascular Function in Atherosclerosis: Complete Statistical AnalysisIndependent statistical analysis of Inflammation and Vascular Function in Atherosclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00760019).
- Infliximab Plus Intravenous Immunoglobulin for the Primary Treatment of Kawasaki Disease: Complete Statistical AnalysisIndependent statistical analysis of Infliximab Plus Intravenous Immunoglobulin for the Primary Treatment of Kawasaki Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- INGEVITY+ Active Fixation Pace/Sense Lead Clinical Study: Complete Statistical AnalysisIndependent statistical analysis of INGEVITY+ Active Fixation Pace/Sense Lead Clinical Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04346537).
- Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia: Complete Statistical AnalysisIndependent statistical analysis of Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03576885).
- INNOVATIONIndependent statistical analysis of A Multicenter, Open Label, Prospective, Non-Randomized Study Of INCRAFT™ In Subjects With AAA (INNOVATION): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- INPACT SFA IIndependent statistical analysis of Randomized Trial of IN.PACT Admiral® Drug Coated Balloon vs Standard PTA for the Treatment of SFA and Proximal Popliteal Arterial Disease: primary endpoint results, effect estimate with confidence…
- InShapeIIIIndependent statistical analysis of CTEPH Identification an Standard Computerised Tomography Pulmonary Angiography in Pulmonary Embolism Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- INSPIRESA detailed statistical analysis of the INSPIRES phase 3 factorial trial of intensive medical therapy for high-risk intracranial or extracranial atherosclerosis, including its design, 90-day stroke endpoint, planned analysis framework, and statistical…
- INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage: Complete Statistical AnalysisIndependent statistical analysis of INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Investigating the Effect of Telmisartan (Micardis®) on the Average 24h Blood Pressure of Therapy-naive and Therapy-experienced Patients: Complete Statistical AnalysisIndependent statistical analysis of Investigating the Effect of Telmisartan (Micardis®) on the Average 24h Blood Pressure of Therapy-naive and Therapy-experienced Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Investigation of the Clinical Performance of Biatain Fiber Ag on Venous Leg Ulcers: Complete Statistical AnalysisIndependent statistical analysis of Investigation of the Clinical Performance of Biatain Fiber Ag on Venous Leg Ulcers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- IONMIndependent statistical analysis of Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00191282).
- IPCIndependent statistical analysis of Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling Pressures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Ipilimumab and Local Radiation for Selected Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Ipilimumab and Local Radiation for Selected Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01769222).
- IRISComplete statistical analysis of the IRIS trial of pioglitazone versus placebo after stroke or myocardial infarction, including trial design, time-to-event endpoints, Cox modeling, mixed-effects analysis, multiplicity, interim analysis, results, and statistical interpretation.
- IRMAIndependent statistical analysis of Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- IRONMANAn independent statistical analysis of IRONMAN (NCT02642562), a randomized phase 4 trial of intravenous ferric derisomaltose in patients with chronic heart failure and iron deficiency.
- ISCHEMIA-EXTENDIndependent statistical analysis of ISCHEMIA-EXTEND, an extended follow-up study evaluating cumulative all-cause, cardiovascular, and non-cardiovascular mortality through Year 10 in patients with coronary artery disease.
- Isthmus Ablation With Gold Electrode for Treatment of Atrial Flutter (AURUM 8): Complete Statistical AnalysisIndependent statistical analysis of Isthmus Ablation With Gold Electrode for Treatment of Atrial Flutter (AURUM 8): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib: Complete Statistical AnalysisIndependent statistical analysis of Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- J-DOIT3An independent statistical analysis of J-DOIT3 (NCT00300976), a randomized parallel-group study of integrated lifestyle treatment for major cardiovascular risk factors in people with type 2 diabetes.
- Jewel Electrophysiology (EP) Lab Study: Complete Statistical AnalysisIndependent statistical analysis of Jewel Electrophysiology (EP) Lab Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05490459).
- KetoPltAggIndependent statistical analysis of IV Ketorolac on Platelet Function Post-Cesarean Delivery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03805607).
- KNOCOUT PEIndependent statistical analysis of An International Pulmonary Embolism Registry Using EKOS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03426124).
- KPL-301 for Subjects With Giant Cell Arteritis: Complete Statistical AnalysisIndependent statistical analysis of KPL-301 for Subjects With Giant Cell Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03827018).
- LEAPSIndependent statistical analysis of Locomotor Experience Applied Post Stroke Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00243919).
- LEFTBASHIndependent statistical analysis of Left Bundle Area Versus Selective His Bundle Pacing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04093414).
- Lenalidomide, Thalidomide and Dexamethasone in Treating Participants With Relapsed or Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Lenalidomide, Thalidomide and Dexamethasone in Treating Participants With Relapsed or Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- LENSIndependent statistical analysis of Lowering Events in Non-proliferative Retinopathy in Scotland: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03439345).
- Less Infections for the Diabetic Foot: Complete Statistical AnalysisIndependent statistical analysis of Less Infections for the Diabetic Foot: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03615807).
- LEVO-CTSIndependent statistical analysis of Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…