Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
965 results
- LIFEStatistical analysis and educational interpretation of the LIFE phase 3 trial of losartan versus atenolol in hypertension and left ventricular hypertrophy, including trial design, the composite cardiovascular endpoint, and planned statistical analysis.
- LINK-HF2Independent statistical analysis of LINK-HF2 - Remote Monitoring Analytics in Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04502563).
- Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab: Complete Statistical AnalysisIndependent statistical analysis of Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- LOCALIZEIndependent statistical analysis of Electrical Coupling Information From The Rhythmia HDx System And DirectSense Technology In Subjects With Paroxysmal Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Long-term Active Surveillance Study for Oral Contraceptives (LASS): Complete Statistical AnalysisIndependent statistical analysis of Long-term Active Surveillance Study for Oral Contraceptives (LASS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00676065).
- Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients: Complete Statistical AnalysisIndependent statistical analysis of Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Long-term Outcomes After Percutaneous Closure of PFO: Complete Statistical AnalysisIndependent statistical analysis of Long-term Outcomes After Percutaneous Closure of PFO: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05558774).
- LOOPAn independent statistical analysis of the LOOP trial of implantable loop recorder monitoring, including trial design, the primary stroke or systemic arterial embolism endpoint, planned time-to-event analysis, and statistical interpretation.
- Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care: Complete Statistical AnalysisIndependent statistical analysis of Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- MADIT-IIAn independent statistical analysis of MADIT-II, a randomized phase 4 trial evaluating remote follow-up of patients receiving an implantable cardioverter defibrillator for prophylactic therapy in ventricular fibrillation and ventricular tachycardia.
- MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation: Complete Statistical AnalysisIndependent statistical analysis of MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Magnesium Supplementation for the Prevention of Supraventricular Arrhythmias: Complete Statistical AnalysisIndependent statistical analysis of Magnesium Supplementation for the Prevention of Supraventricular Arrhythmias: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02837328).
- Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE): Complete Statistical AnalysisIndependent statistical analysis of Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01525875).
- Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia: Complete Statistical AnalysisIndependent statistical analysis of Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- MAP-PAFIndependent statistical analysis of Ablation of the Pulmonary Veins for Paroxysmal Afib: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00744874).
- MARRSIndependent statistical analysis of Millipede AspiRation for Revascularization in Stroke (MARRS) Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05714501).
- MASTER DAPTIndependent statistical analysis of MASTER DAPT, evaluating abbreviated versus prolonged dual antiplatelet therapy after bioresorbable polymer coated stent implantation in patients with high bleeding risk.
- MATOCSSIndependent statistical analysis of Mepolizumab As a Steroid-sparing Treatment Option in the Churg Strauss Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms: Complete Statistical AnalysisIndependent statistical analysis of MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output: Complete Statistical AnalysisIndependent statistical analysis of Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05070572).
- Mechanisms of Chronic Kidney Disease (CKD)-Induced Foam Cell Formation: Complete Statistical AnalysisIndependent statistical analysis of Mechanisms of Chronic Kidney Disease (CKD)-Induced Foam Cell Formation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01671605).
- Mechanisms of Refractory Hypertension (Reserpine): Complete Statistical AnalysisIndependent statistical analysis of Mechanisms of Refractory Hypertension (Reserpine): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03223272).
- MediGuide Registry: Complete Statistical AnalysisIndependent statistical analysis of MediGuide Registry: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02470312).
- Medtronic Resolute Onyx 2.0 mm Clinical Study: Complete Statistical AnalysisIndependent statistical analysis of Medtronic Resolute Onyx 2.0 mm Clinical Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02412501).
- Melatonin in Smoke-induced Vascular Injury: Complete Statistical AnalysisIndependent statistical analysis of Melatonin in Smoke-induced Vascular Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02591238).
- MELODY-1Independent statistical analysis of MELODY-1, a randomized phase 2 study of macitentan versus placebo in subjects with combined pre- and post-capillary pulmonary hypertension due to left ventricular dysfunction, including its primary endpoint,…
- Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation: Complete Statistical AnalysisIndependent statistical analysis of Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Metformin in Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of Metformin in Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02252081).
- Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer: Complete Statistical AnalysisIndependent statistical analysis of Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs: Complete Statistical AnalysisIndependent statistical analysis of Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve: Complete Statistical AnalysisIndependent statistical analysis of Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Midodrine for the Treatment of Refractory Hypotension: Complete Statistical AnalysisIndependent statistical analysis of Midodrine for the Treatment of Refractory Hypotension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01531959).
- Mineralocorticoid Receptor (MR) Antagonist (Eplerenone) vs Amlodipine and STRIATIN: Complete Statistical AnalysisIndependent statistical analysis of Mineralocorticoid Receptor (MR) Antagonist (Eplerenone) vs Amlodipine and STRIATIN: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03683069).
- Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Trial: Complete Statistical AnalysisIndependent statistical analysis of Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02169089).
- MISTIEIndependent statistical analysis of Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00224770).
- MITRA-FRIndependent statistical analysis of MITRA-FR, a randomized multicentre trial of percutaneous MitraClip device implantation in patients with severe secondary mitral regurgitation.
- MITRALIndependent statistical analysis of the MITRAL trial of transcatheter mitral valve replacement in mitral valve disease, including trial design, registry-defined endpoints, statistical methodology, safety, interpretation, and limitations.
- MMPHIndependent statistical analysis of Piloting Mindfulness Meditation Program for Underserved Racial Minority Adults With Pulmonary Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- MMVAR – Velcade: Study of Velcade for the Treatment of Myeloma Patients After Autologous Transplantation: Complete Statistical AnalysisIndependent statistical analysis of MMVAR - Velcade: Study of Velcade for the Treatment of Myeloma Patients After Autologous Transplantation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Monocyte Priming When Consuming a Western Diet: Complete Statistical AnalysisIndependent statistical analysis of Monocyte Priming When Consuming a Western Diet: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05348395).
- MORE-CAREIndependent statistical analysis of MOnitoring REsynchronization deviCes and cARdiac patiEnts: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00885677).
- MORNDIABIndependent statistical analysis of Morbidity in Newly Diagnosed type2 Diabetes in Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02002091).
- MOTIVATE-HFIndependent statistical analysis of MOTIVATional intErviewing to Improve Self-care in Heart Failure Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02894502).
- MOVe-OUTIndependent statistical analysis of the MOVe-OUT randomized trial, including its design, weight-change endpoint, t-test methodology, missing-data approach, reported estimates, confidence intervals, p-values, safety, and statistical interpretation.
- Multicenter Postmarket Surveillance Registry Evaluating Performance and Long Term Safety of the Presillion Stent: Complete Statistical AnalysisIndependent statistical analysis of Multicenter Postmarket Surveillance Registry Evaluating Performance and Long Term Safety of the Presillion Stent: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking: Complete Statistical AnalysisIndependent statistical analysis of Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04518943).
- Myocardial Injury and Quality of Life After COVID-19: Complete Statistical AnalysisIndependent statistical analysis of Myocardial Injury and Quality of Life After COVID-19: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04794062).
- NAMESIndependent statistical analysis of Northwestern University and Access Community Health Network Medication Education Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01578577).