Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
965 results
- NAPSIndependent statistical analysis of Nattokinase Atherothrombotic Prevention Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02080520).
- Nasal EPAP for Stroke Patients With Sleep Apnea: a Pilot Trial.: Complete Statistical AnalysisIndependent statistical analysis of Nasal EPAP for Stroke Patients With Sleep Apnea: a Pilot Trial.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Nashville – Hypertension Management Model: Complete Statistical AnalysisIndependent statistical analysis of Nashville - Hypertension Management Model: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04232124).
- Natriuretic Peptides – Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?: Complete Statistical AnalysisIndependent statistical analysis of Natriuretic Peptides - Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- NAVIGATE ESUSIndependent statistical analysis of NAVIGATE ESUS, a randomized phase 3 trial comparing rivaroxaban with aspirin in patients with recent embolic stroke of undetermined source, including time-to-event methods, primary and secondary results, safety,…
- NB-001 in Children and Adolescents With 22q11 Deletion Syndrome: Complete Statistical AnalysisIndependent statistical analysis of NB-001 in Children and Adolescents With 22q11 Deletion Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05290493).
- NEAT-HFpEFIndependent statistical analysis of the randomized crossover NEAT-HFpEF phase 2 trial evaluating isosorbide mononitrate versus placebo for daily activity in heart failure.
- Nesiritide Use Following Cardiac Surgery in Infants: Complete Statistical AnalysisIndependent statistical analysis of Nesiritide Use Following Cardiac Surgery in Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00281671).
- NeuHFRecoverIndependent statistical analysis of NMES in HF Patients to Improve Functional Recovery Following Hospitalization: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05338437).
- NewGait: A Low-Cost Rehabilitation System to Improve Post-Stroke Gait (Biomechanical Adaptations): Complete Statistical AnalysisIndependent statistical analysis of NewGait: A Low-Cost Rehabilitation System to Improve Post-Stroke Gait (Biomechanical Adaptations): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- NEwTON AFIndependent statistical analysis of Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- NEXISIndependent statistical analysis of Nutrition and Aerobic Exercise in Chronic Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02043574).
- Next Generation X-ray Imaging System: Complete Statistical AnalysisIndependent statistical analysis of Next Generation X-ray Imaging System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04571099).
- NEXT2Independent statistical analysis of Efficacy of Esomeprazole in Patients With Frequent Heartburn: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01370538).
- NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation: Complete Statistical AnalysisIndependent statistical analysis of NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation: primary endpoint results, effect estimate…
- NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study: Complete Statistical AnalysisIndependent statistical analysis of NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03929913).
- NIA-SCOREIndependent statistical analysis of NeuroCognition After Carotid Recanalization: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04219774).
- NIMBUSIndependent statistical analysis of A Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Pomalidomide in Combination With Low-Dose Dexamethasone Versus High-Dose Dexamethasone in Subjects With Refractory Multiple…
- Ninvasive Cardiac Output Measurements During Cesarean Delivery Under Spinal Anesthesia.: Complete Statistical AnalysisIndependent statistical analysis of Ninvasive Cardiac Output Measurements During Cesarean Delivery Under Spinal Anesthesia.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01928797).
- Nitrite Infusion in Islet Cell Transplantation: Complete Statistical AnalysisIndependent statistical analysis of Nitrite Infusion in Islet Cell Transplantation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03544242).
- Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- NMDA Receptors in Motor Learning in Humans: Complete Statistical AnalysisIndependent statistical analysis of NMDA Receptors in Motor Learning in Humans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02082912).
- NOAHComplete statistical analysis of the NOAH phase 3 trial of edoxaban versus ASA or placebo in patients with atrial high rate episodes, including trial design, time-to-event methodology, primary and secondary results, safety,…
- NOBLEIndependent statistical analysis of NOBLE (NCT01496651), a randomized trial comparing percutaneous coronary intervention versus coronary artery bypass graft operation for unprotected left main stenosis.
- NOH303Independent statistical analysis of Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events: Complete Statistical AnalysisIndependent statistical analysis of Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03183063).
- Non-inferiority Study of XM02 Filgrastim (Granix) and Filgrastim (Neupogen) in Combination With Plerixafor for Autologous Stem Cell Mobilization in Patients With Multiple Myeloma or Non-Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Non-inferiority Study of XM02 Filgrastim (Granix) and Filgrastim (Neupogen) in Combination With Plerixafor for Autologous Stem Cell Mobilization in Patients With Multiple Myeloma or Non-Hodgkin Lymphoma: primary endpoint…
- Non-Interventional Study Describing Direct Costs Related to Anti-coagulation Treatment: Complete Statistical AnalysisIndependent statistical analysis of Non-Interventional Study Describing Direct Costs Related to Anti-coagulation Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04435769).
- Non-Invasive Characterization in Cardiac Sarcoidosis: Complete Statistical AnalysisIndependent statistical analysis of Non-Invasive Characterization in Cardiac Sarcoidosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02017522).
- Noninvasive Spinal Stimulation in Stroke: Complete Statistical AnalysisIndependent statistical analysis of Noninvasive Spinal Stimulation in Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03714282).
- NOR-TESTIndependent statistical analysis of the NOR-TEST phase 3 trial comparing tenecteplase versus alteplase for thrombolysis in acute ischemic stroke, including trial design, endpoints, methodology, and statistical interpretation.
- NOR-TEST 2An educational statistical analysis of NOR-TEST 2, a randomized phase 3 trial comparing tenecteplase with alteplase in acute ischemic stroke, focusing on its 90-day favorable functional outcome endpoint and statistical design.
- Normobaric Hyperoxia for Intracerebral Hemorrhage: Complete Statistical AnalysisIndependent statistical analysis of Normobaric Hyperoxia for Intracerebral Hemorrhage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04144868).
- NOTIONAn independent statistical analysis of the NOTION trial, evaluating transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with critical aortic stenosis.
- NOVA2Independent statistical analysis of Inhaled Nitric Oxide and Neuroprotection in Premature Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00515281).
- Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04447846).
- NSAID Use in Postpartum Hypertensive Women: Complete Statistical AnalysisIndependent statistical analysis of NSAID Use in Postpartum Hypertensive Women: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02902172).
- NUCALA® Special Drug Use Investigation (EGPA, Long-term): Complete Statistical AnalysisIndependent statistical analysis of NUCALA® Special Drug Use Investigation (EGPA, Long-term): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03557060).
- OASIS Wound Matrix (Oasis) Mechanism of Action: Complete Statistical AnalysisIndependent statistical analysis of OASIS Wound Matrix (Oasis) Mechanism of Action: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00570141).
- OASIS-5Independent statistical analysis of OASIS-5, a randomized phase 3 trial comparing fondaparinux with enoxaparin in thromboembolism, including its design, primary endpoints, planned statistical analysis, and interpretation.
- OASIS-6An independent statistical analysis of OASIS-6, a randomized phase 3 trial evaluating fondaparinux versus control therapy in patients with ST-segment elevation acute myocardial infarction.
- OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE): Complete Statistical AnalysisIndependent statistical analysis of OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE): primary endpoint results, effect estimate with confidence…
- OATIndependent statistical analysis of Oral Anticoagulation Therapy Pilot Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01959425).
- OCEANIndependent statistical analysis of Randomized Study of Obicetrapib in Combination With Ezetimibe: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04770389).
- ODENIndependent statistical analysis of ODEN Trial: Option vs. Denali IVC Filters: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02201277).
- ODYSSEY OUTCOMESComplete statistical analysis of ODYSSEY OUTCOMES, the randomized phase 3 trial of alirocumab versus placebo after acute coronary syndrome, including time-to-event endpoints, hazard ratios, stratified log-rank testing, multiplicity, safety, and statistical interpretation.
- OLE-IEDATIndependent statistical analysis of Extension Treatment Using EryDex System in Patients With AT Who Participated in the ATTeST-IEDAT-02-2015 Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Olmesartan Comparison to Losartan in Hypertensive Subjects: Complete Statistical AnalysisIndependent statistical analysis of Olmesartan Comparison to Losartan in Hypertensive Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00949884).
- Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Medoxomil 40 mg Monotherapy in Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Medoxomil 40 mg Monotherapy in Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Omacor Plus Standard Therapies In Post Myocardial Infarction (MI) Subjects Evaluation: The OPTIMISE Observational Study: Complete Statistical AnalysisIndependent statistical analysis of Omacor Plus Standard Therapies In Post Myocardial Infarction (MI) Subjects Evaluation: The OPTIMISE Observational Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…