Cardiovascular Clinical Trials

Statistical methods in cardiovascular trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All cardiovascular trials

672 results

• A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma: primary endpoint…Phase 1Results postedn = 13NCT05121103
• A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 13NCT01028651
• A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 123NCT02316106
• A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 400NCT04960280
• A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension: primary endpoint results,…Phase 2Results postedn = 48NCT06336356
• A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve…Phase 3Results postedn = 507NCT01456169
• A Study to Evaluate the Effects of 3 Months Dosing With GW856553, as Assessed FDG-PET/CT Imaging: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effects of 3 Months Dosing With GW856553, as Assessed FDG-PET/CT Imaging: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 99NCT00633022
• A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 111NCT00866359
• A Study to Evaluate the Efficacy and Safety of Rivaroxaban Venous Thromboembolism (VTE) Prophylaxis in Ambulatory Cancer Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Rivaroxaban Venous Thromboembolism (VTE) Prophylaxis in Ambulatory Cancer Participants: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 841NCT02555878
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).: primary endpoint results, effect estimate with confidence interval,…Phase 1Results postedn = 24NCT03923738
• A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 20NCT00914966
• A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVO: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVO: primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 34NCT06176963
• A Study to Evaluate the Use and Safety of CARDIOLITE® in Pediatric Patients With Kawasaki Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Use and Safety of CARDIOLITE® in Pediatric Patients With Kawasaki Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 445NCT00162032
• A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody: primary…Phase 2Results postedn = 221NCT03525678
• A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin’s Lymphomas, Solid Tumors and Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas,…Phase 1Results postedn = 41NCT02082977
• A Sugar-Sweetened Beverage Reduction Intervention for Native American Men: Complete Statistical AnalysisIndependent statistical analysis of A Sugar-Sweetened Beverage Reduction Intervention for Native American Men: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06029517).Phase NAResults postedn = 48NCT06029517
• A Trial of Behavioral Economic Interventions to Reduce Cardiovascular Disease (CVD) Risk: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Behavioral Economic Interventions to Reduce Cardiovascular Disease (CVD) Risk: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 1,503NCT01346189
• A Trial of Telemonitoring in Adults With Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Telemonitoring in Adults With Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01393314).Phase NAResults postedn = 99NCT01393314
• A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program: Complete Statistical AnalysisIndependent statistical analysis of A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 60NCT05144737
• AAA CEUSIndependent statistical analysis of Evaluation of Contrast-Enhanced Ultrasound to Detect Endoleaks After Endovascular Aortic Aneurysm Repair: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 20NCT01005212
• AATACA detailed statistical analysis of the randomized phase 4 AATAC trial comparing atrial fibrillation ablation with amiodarone in patients with heart failure and an ICD, including trial design, endpoints, planned analysis, and…Phase 4n = 203NCT00729911
• Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu’s Arteritis: Complete Statistical AnalysisIndependent statistical analysis of Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 97NCT00556439
• Abatacept in Treating Adults With Mild Relapsing Wegener’s Granulomatosis: Complete Statistical AnalysisIndependent statistical analysis of Abatacept in Treating Adults With Mild Relapsing Wegener's Granulomatosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00468208).Phase 1/2Results postedn = 20NCT00468208
• ABCIndependent statistical analysis of Arrythmia Burden in Cardiac Contractility Modulation (CCM): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05704426).Phase NAResults postedn = 2NCT05704426
• ABLATORIndependent statistical analysis of ABLATOR Ablation Observational Registry: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02344173).Phase NAResults postedn = 2,035NCT02344173
• ABSORB EXTENDIndependent statistical analysis of ABSORB EXTEND Clinical Investigation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01023789).Phase NAResults postedn = 812NCT01023789
• Absorb IV Randomized Controlled Trial: Complete Statistical AnalysisIndependent statistical analysis of Absorb IV Randomized Controlled Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02173379).Phase NAResults postedn = 2,604NCT02173379
• ACCELERATEComplete statistical analysis of ACCELERATE (NCT01687998), a randomized phase 3 study of evacetrapib versus placebo in high-risk vascular disease, including trial design, composite cardiovascular endpoints, Cox modeling, ANOVA, confidence intervals, p-values, and…Phase 3Results postedn = 12,092NCT01687998
• Accent CardiacIndependent statistical analysis of Accent Cardiac MRI Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02041702).Phase NAResults postedn = 283NCT02041702
• ACCOASTIndependent statistical analysis of A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 4,033NCT01015287
• ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients: Complete Statistical AnalysisIndependent statistical analysis of ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01867047).Phase NAResults postedn = 59NCT01867047
• Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm: Complete Statistical AnalysisIndependent statistical analysis of Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00585559).Phase 3Results postedn = 44NCT00585559
• ACHIEVEIndependent statistical analysis of Albumin for Intracerebral Hemorrhage Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00990509).Phase 2Results postedn = 14NCT00990509
• ACIPAn independent statistical analysis of the randomized phase 3 ACIP study of treatment strategies for asymptomatic cardiac ischemia, based on the ClinicalTrials.gov record.Phase 3NCT00000478
• AcTIndependent statistical analysis of the randomized phase 3 AcT trial comparing alteplase and tenecteplase in patients with acute ischemic stroke, including trial design, the modified Rankin Scale primary endpoint, planned analysis, statistical…Phase 3n = 1,600NCT03889249
• ACT IIndependent statistical analysis of ACT I (NCT00106938), a randomized trial comparing carotid artery stenting with filter versus carotid artery endarterectomy in asymptomatic subjects with significant extracranial carotid stenotic disease.Phase NAResults postedn = 1,663NCT00106938
• ACT IIndependent statistical analysis of Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I): primary endpoint results,…Phase NAResults postedn = 1,663NCT00106938
• ACTIONIndependent statistical analysis of Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 451NCT00760266
• ACTIVE-WAn independent statistical analysis of ACTIVE-W (NCT00243178), a randomized phase 3 trial evaluating clopidogrel in atrial fibrillation and vascular risk, including its time-to-event endpoint, trial design, planned statistical analysis, and interpretation.Phase 3n = 6,706NCT00243178
• Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia: Complete Statistical AnalysisIndependent statistical analysis of Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04984239).Phase NAResults postedn = 20NCT04984239
• Adaptive Hip Exoskeleton for Stroke Gait Enhancement: Complete Statistical AnalysisIndependent statistical analysis of Adaptive Hip Exoskeleton for Stroke Gait Enhancement: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05536739).Phase NAResults postedn = 12NCT05536739
• Adherence and Intensification of Medications (AIM) Implementation Study: Complete Statistical AnalysisIndependent statistical analysis of Adherence and Intensification of Medications (AIM) Implementation Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00495794).Phase NAResults postedn = 4,622NCT00495794
• ADIOSIndependent statistical analysis of Arrhythmia Detection In Obstructive Sleep Apnea (ADIOS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02743520).Phase NAResults postedn = 86NCT02743520
• Adjunct Low Frequency Repetitive Transcranial Magnetic Stimulation With Physiotherapy Enhance Upper Extremity Function Restoration: Complete Statistical AnalysisIndependent statistical analysis of Adjunct Low Frequency Repetitive Transcranial Magnetic Stimulation With Physiotherapy Enhance Upper Extremity Function Restoration: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 24NCT02490371
• ADORE BRAINIndependent statistical analysis of Brain Health in Midlife: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06640842).Phase NAResults postedn = 24NCT06640842
• ADVANCEIndependent statistical analysis of the ADVANCE phase 3 trial of blood pressure and glucose lowering for prevention of vascular disease in high-risk patients with type 2 diabetes, including its factorial design, composite…Phase 3n = 11,140NCT00145925
• ADVANCEIndependent statistical analysis of Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02499679).Phase NAResults postedn = 4,737NCT02499679
• Advance Cardiac Resynchronization Therapy (CRT) Registry: Complete Statistical AnalysisIndependent statistical analysis of Advance Cardiac Resynchronization Therapy (CRT) Registry: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01805154).Phase NAResults postedn = 1,529NCT01805154
• ADVANCE-2Independent statistical analysis of the ADVANCE-2 phase 3 trial of apixaban versus enoxaparin for prevention of thrombosis-related events following knee replacement surgery, including endpoint definitions, risk ratios, risk differences, sequential testing, bleeding…Phase 3Results postedn = 3,221NCT00452530
• Advisor HD Grid Observational Study: Complete Statistical AnalysisIndependent statistical analysis of Advisor HD Grid Observational Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03733392).Phase NAResults postedn = 379NCT03733392

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