Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
672 results
- ATTRACTIndependent statistical analysis of Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00790335).
- ATTRibute-CMIndependent statistical analysis of Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- AVAIIndependent statistical analysis of AVAI: Atrial Ventricular Arrythmia Incidence: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00832975).
- AVERROESIndependent statistical analysis of A Phase III Study of Apixaban in Patients With Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- AXIOMATIC-SSPA detailed statistical analysis of AXIOMATIC-SSP, evaluating BMS-986177 in patients with acute ischemic stroke or transient ischemic attack receiving aspirin and clopidogrel, including MCP-Mod dose-response analysis, relative risks, confidence intervals, and safety…
- AZALEA-TIMI 71Complete statistical analysis of AZALEA-TIMI 71, a randomized phase 2 trial comparing abelacimab with rivaroxaban in patients with atrial fibrillation, including bleeding endpoints, hazard ratios, confidence intervals, and statistical methodology.
- BALATONIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion: primary endpoint results, effect estimate with confidence…
- Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension – CATALYST: Complete Statistical AnalysisIndependent statistical analysis of Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- BARIIndependent statistical analysis of the Bypass Angioplasty Revascularization Investigation (BARI), a randomized phase 3 trial comparing percutaneous coronary angioplasty and coronary artery bypass in cardiovascular and coronary disease.
- BASICSIndependent statistical analysis of BASICS (NCT01717755), a randomized parallel-group study of intra-arterial treatment in basilar artery thrombosis and related basilar artery occlusive conditions, including its day-90 favourable-outcome endpoint and planned statistical interpretation.
- Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud’s Phenomenon: Complete Statistical AnalysisIndependent statistical analysis of Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud's Phenomenon: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- BenidipineTRIndependent statistical analysis of Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06808321).
- BESTIndependent statistical analysis of BEST (NCT02441556), a randomized parallel-group trial comparing endovascular treatment with standard medical therapy for acute basilar artery occlusion, including its modified Rankin Scale endpoint and planned statistical interpretation.
- BETAIndependent statistical analysis of Behavioral Economics to Improve Antihypertensive Therapy Adherence: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04029883).
- Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison: Complete Statistical AnalysisIndependent statistical analysis of Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01002456).
- BETonMACEComplete statistical analysis of the BETonMACE phase 3 trial of apabetalone versus placebo in high-risk patients with type 2 diabetes and coronary artery disease, including time-to-event methodology, hazard ratios, confidence intervals, p-values,…
- BevacizumabIndependent statistical analysis of A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- BFFIndependent statistical analysis of Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03496545).
- BingocizeIndependent statistical analysis of Bingocize: A Novel Mobile Application for Older Adult Health: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03629912).
- Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306): Complete Statistical AnalysisIndependent statistical analysis of Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Bipolar Ventricular Tachycardia (VT) Study: Complete Statistical AnalysisIndependent statistical analysis of Bipolar Ventricular Tachycardia (VT) Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02374476).
- BLOCk-CTIIndependent statistical analysis of Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Blood Flow Stimulation in the Lower Limbs by Application of Different External Devices: Complete Statistical AnalysisIndependent statistical analysis of Blood Flow Stimulation in the Lower Limbs by Application of Different External Devices: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Bortezomib in Treating Patients With Newly Diagnosed Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Bortezomib in Treating Patients With Newly Diagnosed Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00075881).
- Bortezomib, Doxorubicin Hydrochloride Liposome, and Dexamethasone Followed by Thalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Bortezomib, Doxorubicin Hydrochloride Liposome, and Dexamethasone Followed by Thalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Multiple Myeloma: primary endpoint results, effect estimate with confidence…
- Botox + FESIndependent statistical analysis of Efficacy of Functional Electrical Stimulation (FES) in Persons Receiving Botulinum Neurotoxin for Upper Extremity Spasticity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- BotticelliIndependent statistical analysis of Effectiveness and Safety of Combination of Nebivolol and Amlodipine in Hypertensive Patients Versus Each Monotherapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- BRANCHIndependent statistical analysis of Bare Metal Bifurcation Stent Clinical Trial in Humans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00607321).
- BRAVOIndependent statistical analysis of A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRAVO): primary endpoint results, effect estimate with…
- Bridging the Evidence-to-practice Gap: Complete Statistical AnalysisIndependent statistical analysis of Bridging the Evidence-to-practice Gap: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03713515).
- BROADWAYA detailed statistical analysis of the phase 3 BROADWAY trial evaluating obicetrapib on top of maximum tolerated lipid-modifying therapies in patients with dyslipidemias and high cardiovascular risk.
- Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- C-Pulse IDE Feasibility Study- A Heart Assist System: Complete Statistical AnalysisIndependent statistical analysis of C-Pulse IDE Feasibility Study- A Heart Assist System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00815880).
- C1 Esterase Inhibitor (C1INH-nf) for the Treatment of Acute Hereditary Angioedema (HAE) Attacks: Complete Statistical AnalysisIndependent statistical analysis of C1 Esterase Inhibitor (C1INH-nf) for the Treatment of Acute Hereditary Angioedema (HAE) Attacks: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- C1 Esterase Inhibitor in Hereditary Angioedema (HAE)(Extension Study): Complete Statistical AnalysisIndependent statistical analysis of C1 Esterase Inhibitor in Hereditary Angioedema (HAE)(Extension Study): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00292981).
- CADENCEIndependent statistical analysis of the CADENCE phase 2 trial of sotatercept for pulmonary hypertension due to HFpEF, covering its randomized design, pulmonary vascular resistance endpoint, planned analysis, and statistical interpretation.
- CADENCE-MISIndependent statistical analysis of EDWARDS INTUITY Valve System CADENCE-MIS Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02672553).
- CAESARIndependent statistical analysis of Candesartan Effect in Second Stage Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00621153).
- CAFIIndependent statistical analysis of Coil Assisted Flow Diversion Safety and Performance Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04187573).
- CAIROAn independent statistical analysis of the randomized phase 4 CAIRO trial of clopidogrel and aspirin in ischemic cerebrovascular accident, covering trial design, neurologic endpoints, planned analyses, statistical interpretation, and limitations.
- Calf Deep Vein Thrombosis Treatment Trial: Complete Statistical AnalysisIndependent statistical analysis of Calf Deep Vein Thrombosis Treatment Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03590743).
- CAMTAFIndependent statistical analysis of Catheter Ablation Versus Medical Treatment of AF in Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01411371).
- Candesartan Cilexetil / Hydrochlorothiazide Combination Tablets Special Drug Use Surveillance: Long-term Use (12 Months): Complete Statistical AnalysisIndependent statistical analysis of Candesartan Cilexetil / Hydrochlorothiazide Combination Tablets Special Drug Use Surveillance: Long-term Use (12 Months): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Cangrelor Ticagrelor Transition Study: Complete Statistical AnalysisIndependent statistical analysis of Cangrelor Ticagrelor Transition Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01766466).
- CANTOSAn independent statistical analysis of the phase 3 CANTOS trial (NCT01327846), comparing three canakinumab doses with placebo for first adjudicated major adverse cardiovascular events in 10066 participants with atherosclerosis, with hazard ratios,…
- CAPPSIndependent statistical analysis of Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00135707).
- CAPSYSIndependent statistical analysis of Computer-Aided Prevention System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02444715).