Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
837 results
- Clinical Evaluation of the OEC Elite Vascular Mobile Fluoroscopy System: Complete Statistical AnalysisIndependent statistical analysis of Clinical Evaluation of the OEC Elite Vascular Mobile Fluoroscopy System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03096483).
- Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve: Complete Statistical AnalysisIndependent statistical analysis of Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00630916).
- Clinical Study of Lipoic Acid on Ischemic Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of Clinical Study of Lipoic Acid on Ischemic Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03491969).
- Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers: Complete Statistical AnalysisIndependent statistical analysis of Clinical Study to Compare Two Skin Substitute Categories for Their Effectiveness to Treat Diabetic Foot Ulcers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices: Complete Statistical AnalysisIndependent statistical analysis of Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01130896).
- CLOSEA statistical analysis of the CLOSE phase 3 trial evaluating patent foramen ovale closure or anticoagulants versus antiplatelet therapy to prevent stroke recurrence.
- CLOTBUST-HFIndependent statistical analysis of CLOTBUST Hands-Free: A Phase I/II Pilot Safety Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01240356).
- CLOTS 3Independent statistical analysis of CLOTS 3 (NCT00789542), a phase 3 randomized trial evaluating intermittent pneumatic compression to prevent post-stroke deep vein thrombosis.
- COAPTIndependent statistical analysis of the COAPT trial (NCT01626079), evaluating MitraClip in symptomatic heart failure with functional mitral regurgitation, including trial design, primary safety analysis, recurrent hospitalization, win ratio methodology, and statistical interpretation.
- COCOA-PADIndependent statistical analysis of Cocoa to Improve Walking Performance in Peripheral Artery Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02876887).
- Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: Complete Statistical AnalysisIndependent statistical analysis of Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05860127).
- COMIC-ASIndependent statistical analysis of COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04420325).
- COMMANDER HFIndependent statistical analysis of A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery…
- COMMIT-CCS-2An educational statistical analysis of COMMIT-CCS-2, a randomized, double-blind, factorial phase 4 trial evaluating clopidogrel and metoprolol in acute myocardial infarction, with emphasis on factorial design and its primary endpoints.
- Common Safety Follow-up Trial of Tecemotide (L-BLP25): Complete Statistical AnalysisIndependent statistical analysis of Common Safety Follow-up Trial of Tecemotide (L-BLP25): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01423760).
- Comparative Effectiveness of Rehabilitation Services for Survivors of Acute Ischemic Stroke: Complete Statistical AnalysisIndependent statistical analysis of Comparative Effectiveness of Rehabilitation Services for Survivors of Acute Ischemic Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing: Complete Statistical AnalysisIndependent statistical analysis of Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- COMPAREIndependent statistical analysis of A Comparison of the Pacemaker Automatic Features in Reduction of Ventricular Pacing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- COMPAREIndependent statistical analysis of A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure: primary endpoint results, effect estimate with…
- Compare Technegas Ventilation-Perfusion SPECT and Xenon Ventilation-Perfusion Planar Imaging for Pulmonary Embolism: Complete Statistical AnalysisIndependent statistical analysis of Compare Technegas Ventilation-Perfusion SPECT and Xenon Ventilation-Perfusion Planar Imaging for Pulmonary Embolism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease: Complete Statistical AnalysisIndependent statistical analysis of Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Comparison Between NICOM-Cheetah and Flotrac-Vigileo for Cardiac Output Monitoring.: Complete Statistical AnalysisIndependent statistical analysis of Comparison Between NICOM-Cheetah and Flotrac-Vigileo for Cardiac Output Monitoring.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03394768).
- Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing: Complete Statistical AnalysisIndependent statistical analysis of Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Comparison of Two High-intensity Gait Training Interventions on Contraversive Pushing Behaviors in Individuals Poststroke: Complete Statistical AnalysisIndependent statistical analysis of Comparison of Two High-intensity Gait Training Interventions on Contraversive Pushing Behaviors in Individuals Poststroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- COMPASSIndependent statistical analysis of A Novel Transition Program to Reduce Disability After Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03485820).
- COMPASSIndependent statistical analysis of Comprehensive Post-Acute Stroke Services: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02588664).
- COMPASS AFIndependent statistical analysis of COMPASS AF, a randomized trial comparing anatomy-based ablation with map-guided substrate ablation for persistent atrial fibrillation, including its binary recurrence endpoint and planned statistical interpretation.
- ComPLETIndependent statistical analysis of Comparing Peripherally Inserted Central Catheters to Long Peripheral Catheters in Pediatrics: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- COMPLETEIndependent statistical analysis of the COMPLETE trial (NCT01740479), evaluating complete versus culprit-only revascularization after early PCI for STEMI, including trial design, endpoints, planned statistical methodology, and interpretation.
- Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture: Complete Statistical AnalysisIndependent statistical analysis of Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- CONFIDENCE-HFIndependent statistical analysis of COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- CONNECTIndependent statistical analysis of Chronic Total Occlusion Crossing With the Wildcat Catheter: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01174784).
- Connected Healthcare for Individuals Living at Home With Chronic Conditions: Complete Statistical AnalysisIndependent statistical analysis of Connected Healthcare for Individuals Living at Home With Chronic Conditions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04339296).
- CONSENSUSAn independent statistical analysis of the CONSENSUS trial (NCT07334353), a Delphi study evaluating expert consensus on pre- and post-procedure skincare protocols for aesthetic treatments.
- ConsultaTM CRT-D Clinical Evaluation Study: Complete Statistical AnalysisIndependent statistical analysis of ConsultaTM CRT-D Clinical Evaluation Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00526162).
- COREVALVEAn independent statistical analysis and educational interpretation of the COREVALVE trial of the CoreValve Evolut 34R TAVR system in aortic valve stenosis, including trial design, registry-defined endpoints, planned statistical methods, and reported…
- Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI): Complete Statistical AnalysisIndependent statistical analysis of Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00353795).
- Coronary MDCTA With Iopamidol Injection 370: Complete Statistical AnalysisIndependent statistical analysis of Coronary MDCTA With Iopamidol Injection 370: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00558792).
- CorPath® GRX Neuro Study: Complete Statistical AnalysisIndependent statistical analysis of CorPath® GRX Neuro Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04236856).
- COSMOSIndependent statistical analysis of A Study Assessing Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain: Complete Statistical AnalysisIndependent statistical analysis of Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- CPCIndependent statistical analysis of Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- CPIT001Independent statistical analysis of Check Point Inhibition After Autologous Stem Cell Transplantation in Patients at High Risk of Post Transplant Recurrence: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- CRATUSIndependent statistical analysis of AllogeneiC Human Mesenchymal Stem Cells (hMSC) in Patients With Aging FRAilTy Via IntravenoUS Delivery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- CREST-2Independent statistical analysis of CREST-2, a randomized trial of carotid revascularization and intensive medical management for asymptomatic carotid stenosis, including its design, primary endpoint, planned statistical analysis, and interpretation.
- CRYO-AFIndependent statistical analysis of Evaluation of the Cardioblate CryoFlex Surgical Ablation System in Longstanding Persistent Atrial Fibrillation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Cryoablation System FIM/CE Mark Study: Complete Statistical AnalysisIndependent statistical analysis of Cryoablation System FIM/CE Mark Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03723070).
- CSPOTIndependent statistical analysis of Conduction System Pacing Optimized Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04905290).
- CTREPHIndependent statistical analysis of Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- CULPRIT-SHOCKIndependent statistical analysis of CULPRIT-SHOCK, the randomized trial comparing culprit lesion only PCI versus multivessel PCI in patients with cardiogenic shock.