Statistical methods in cardiovascular trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
Hazard ratio
ANCOVA
Cox proportional-hazards model
Non-inferiority trial design
Multiple imputation / missing data
Odds ratio
Log-rank test
t-test
All cardiovascular trials
965 results
- CSPOTIndependent statistical analysis of Conduction System Pacing Optimized Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04905290).
- CTREPHIndependent statistical analysis of Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- CULPRIT-SHOCKIndependent statistical analysis of CULPRIT-SHOCK, the randomized trial comparing culprit lesion only PCI versus multivessel PCI in patients with cardiogenic shock.
- Curing Atrial Fibrillation in Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of Curing Atrial Fibrillation in Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00292162).
- Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients: Complete Statistical AnalysisIndependent statistical analysis of Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02544503).
- CV_WIZARDIndependent statistical analysis of CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- CVT-ISR First in Human Trial for Coronary In-Stent Restenosis: Complete Statistical AnalysisIndependent statistical analysis of CVT-ISR First in Human Trial for Coronary In-Stent Restenosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05731700).
- Cyclophosphamide, Carfilzomib, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Active Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Cyclophosphamide, Carfilzomib, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Active Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- D-dimer to Predict Recurrence in Patients With Multiple Episodes of Venous Thromboembolism: Complete Statistical AnalysisIndependent statistical analysis of D-dimer to Predict Recurrence in Patients With Multiple Episodes of Venous Thromboembolism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- D&DIndependent statistical analysis of Dyslipidemia and Diabetic Retinopathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03403283).
- Dabigatran Etexilate for Stroke Prevention in Patients With Atrial Fibrillation and Mild to Moderate Renal Impairment: Complete Statistical AnalysisIndependent statistical analysis of Dabigatran Etexilate for Stroke Prevention in Patients With Atrial Fibrillation and Mild to Moderate Renal Impairment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- DACABIndependent statistical analysis of Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02201771).
- dal-GenEComplete statistical analysis of the phase 3 dal-GenE trial evaluating dalcetrapib versus placebo in a genetically defined population with a recent acute coronary syndrome, including trial design, time-to-event endpoints, Cox modeling, multiplicity,…
- dal-GenEIndependent statistical analysis of Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Dalteparin for Primary Venous Thromboembolism (VTE) Prophylaxis in Pancreatic Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Dalteparin for Primary Venous Thromboembolism (VTE) Prophylaxis in Pancreatic Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- DANAMI-3 PRIMULTIAn independent statistical analysis of DANAMI-3 PRIMULTI, a randomized clinical trial evaluating culprit-lesion-only versus complete revascularization strategies in patients with ST-elevation myocardial infarction and multivessel disease.
- DAPTIndependent statistical analysis of the DAPT phase 4 trial evaluating switching from dual antiplatelet therapy to low-dose rivaroxaban plus aspirin in patients with coronary artery disease, including trial design, platelet aggregation endpoint,…
- Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab: Complete Statistical AnalysisIndependent statistical analysis of Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Data Analysis for Drug Repurposing for Effective Alzheimer’s Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol: Complete Statistical AnalysisIndependent statistical analysis of Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- DATASIndependent statistical analysis of DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00157820).
- DECLARE-TIMI 58Independent statistical analysis of DECLARE-TIMI 58, a completed healthcare-claims replication study comparing dapagliflozin with a DPP-4 inhibitor in diabetes, including its design, composite endpoint, planned time-to-event analysis, and statistical interpretation.
- DeFACTOIndependent statistical analysis of Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01233518).
- DEFEAT-PEIndependent statistical analysis of Detect Fluid Early From Intra-thoracic Impedance Monitoring: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00916929).
- DEFINE AFibIndependent statistical analysis of DEFINE AFib (Atrial Fibrillation): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04926857).
- DEFUSE 3Independent statistical analysis of Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02586415).
- DELIVERIndependent statistical analysis of the DELIVER phase 3 trial of dapagliflozin in heart failure with preserved ejection fraction, including its dual primary time-to-event endpoints, Cox models, recurrent-event analysis, KCCQ analysis, safety, and…
- DELIVERIndependent statistical analysis of Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Deployment of American Heart Association Heart Failure Protocols and Content Within the Intel® Health Guide System: Complete Statistical AnalysisIndependent statistical analysis of Deployment of American Heart Association Heart Failure Protocols and Content Within the Intel® Health Guide System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Developing a Non-invasive Cardiac Functional Health Status Measurement Device: Complete Statistical AnalysisIndependent statistical analysis of Developing a Non-invasive Cardiac Functional Health Status Measurement Device: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01877343).
- Deviating the Esophagus in Atrial Fibrillation Ablation: Complete Statistical AnalysisIndependent statistical analysis of Deviating the Esophagus in Atrial Fibrillation Ablation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01546168).
- DEVOTEIndependent statistical analysis of DEVOTE (NCT01959529), the double-blind cardiovascular outcomes trial of insulin degludec versus insulin glargine in 7637 people with type 2 diabetes, covering the Cox non-inferiority analysis of MACE, negative…
- DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia: Complete Statistical AnalysisIndependent statistical analysis of DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- DFCI 10-106Independent statistical analysis of Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- DFUMATIndependent statistical analysis of Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care: Complete Statistical AnalysisIndependent statistical analysis of Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- DIAS-2Independent statistical analysis of the randomized phase 3 DIAS-2 trial of desmoteplase in acute ischemic stroke, including its design, functional endpoints, planned statistical analysis, and interpretation.
- Dietary Nitrate and Physiological Aging: Complete Statistical AnalysisIndependent statistical analysis of Dietary Nitrate and Physiological Aging: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02593305).
- Dietary Nitrate for Heart Failure: Complete Statistical AnalysisIndependent statistical analysis of Dietary Nitrate for Heart Failure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01682356).
- DIGIndependent statistical analysis of the randomized phase 3 DIG trial of digoxin versus placebo in acute heart failure, including its design, 30-day mortality and rehospitalization endpoint, planned statistical methodology, and interpretation.
- Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02981082).
- DIRECT-MTIndependent statistical analysis of DIRECT-MT (NCT03469206), a randomized trial of intra-arterial thrombectomy versus intravenous thrombolysis in patients with acute ischemic stroke and large vessel occlusion.
- Discrete Versus Rhythmic Gait Training: Complete Statistical AnalysisIndependent statistical analysis of Discrete Versus Rhythmic Gait Training: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02650440).
- Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation: Complete Statistical AnalysisIndependent statistical analysis of Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02010151).
- Distal Renal Denervation: Complete Statistical AnalysisIndependent statistical analysis of Distal Renal Denervation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02667912).
- DIVAIndependent statistical analysis of Dual Site Left Ventricular (LV) Pacing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00944125).
- DOAC LVADIndependent statistical analysis of Evaluation of the Hemocompatibility of the Direct Oral Anti-Coagulant Apixaban in Left Ventricular Assist Devices: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- DOCSIndependent statistical analysis of Depression Outpatient Cardiology Screening Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01552889).
- Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene: Complete Statistical AnalysisIndependent statistical analysis of Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval,…
- Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…