Cardiovascular Clinical Trials

Statistical methods in cardiovascular trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All cardiovascular trials

965 results

• Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer: Complete Statistical AnalysisIndependent statistical analysis of Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 1/2Results postedn = 31NCT00963872
• Dose Finding Study of HP802-247 in Venous Leg Ulcers: Complete Statistical AnalysisIndependent statistical analysis of Dose Finding Study of HP802-247 in Venous Leg Ulcers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00852995).Phase 2Results postedn = 228NCT00852995
• Dose Response Effects of Marine Omega-3 Fatty Acids on Inflammation: Complete Statistical AnalysisIndependent statistical analysis of Dose Response Effects of Marine Omega-3 Fatty Acids on Inflammation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01078909).Phase 3Results postedn = 125NCT01078909
• DREAMM 5Independent statistical analysis of Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM): primary endpoint results, effect estimate with confidence interval,…Phase 1/2Results postedn = 208NCT04126200
• Driving Neuroplasticity With Nerve Stimulation and Modified CIT: Complete Statistical AnalysisIndependent statistical analysis of Driving Neuroplasticity With Nerve Stimulation and Modified CIT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02587234).Phase 1/2Results postedn = 21NCT02587234
• Drug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of Drug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 20NCT01196871
• E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03863509).Phase NAResults postedn = 450NCT03863509
• EARLY TAVRIndependent statistical analysis of EARLY TAVR (NCT03042104), evaluating TAVR compared with surveillance in patients with asymptomatic severe aortic stenosis, including trial design, the primary composite endpoint, planned statistical analysis, and interpretation.Phase NAn = 901NCT03042104
• EARLY-AFAn educational statistical analysis of EARLY-AF, a randomized parallel pilot study evaluating electroporation-based AF ablation in patients with atrial fibrillation and heart failure with preserved ejection fraction.Phase NAn = 200NCT07385417
• EASE TRICUSPID Expertise-based Assessment Study on Clinical Efficacy of Contour 3D® in TRICUSPID Valve Annuloplasty: Complete Statistical AnalysisIndependent statistical analysis of EASE TRICUSPID Expertise-based Assessment Study on Clinical Efficacy of Contour 3D® in TRICUSPID Valve Annuloplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 85NCT01532921
• EASSIIndependent statistical analysis of EASSI - Evaluation of the Safety of Self-Administration With Icatibant: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00997204).Phase 3Results postedn = 151NCT00997204
• EAST-AFNET 4Independent statistical analysis and educational interpretation of EAST-AFNET 4, a randomized phase 4 trial evaluating early standardized rhythm control in atrial fibrillation.Phase 4n = 2,789NCT01288352
• Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease: Complete Statistical AnalysisIndependent statistical analysis of Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease: primary endpoint results, effect estimate with confidence interval,…Phase 3Results postedn = 168NCT03395639
• EDUCATEIndependent statistical analysis of EDUCATE: The MEDTRONIC Endeavor Drug Eluting Stenting: Understanding Care, Antiplatelet Agents and Thrombotic Events: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 2,272NCT01069003
• Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention: Complete Statistical AnalysisIndependent statistical analysis of Effect of Acute Statin Treatment in Patients Undergoing Percutaneous Coronary Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 57NCT00588471
• Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke: Complete Statistical AnalysisIndependent statistical analysis of Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 120NCT03112473
• Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution: Complete Statistical AnalysisIndependent statistical analysis of Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 70NCT03255187
• Effect of Eleclazine on Shortening of the QT Interval, Safety, and Tolerability in Adults With Long QT Syndrome Type 3: Complete Statistical AnalysisIndependent statistical analysis of Effect of Eleclazine on Shortening of the QT Interval, Safety, and Tolerability in Adults With Long QT Syndrome Type 3: primary endpoint results, effect estimate with confidence interval,…Phase 3Results postedn = 41NCT02300558
• Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina: Complete Statistical AnalysisIndependent statistical analysis of Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 1NCT01549977
• Effect of Nike FuelBand on Exercise and Function in Claudicants; a Randomised Controlled Trial: Complete Statistical AnalysisIndependent statistical analysis of Effect of Nike FuelBand on Exercise and Function in Claudicants; a Randomised Controlled Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 37NCT01822457
• Effect of Raltegravir on Endothelial Function in HIV-Infected Patients: Complete Statistical AnalysisIndependent statistical analysis of Effect of Raltegravir on Endothelial Function in HIV-Infected Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00843713).Phase 4Results postedn = 56NCT00843713
• Effectiveness of Dispatch-Assisted Cardiopulmonary Resuscitation (CPR) Instructions: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Dispatch-Assisted Cardiopulmonary Resuscitation (CPR) Instructions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00664443).Phase NAResults postedn = 2,260NCT00664443
• Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study): Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 102NCT00687076
• Effectiveness of SMS Text Reminders to Improve Blood Pressure Among Patients With Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of SMS Text Reminders to Improve Blood Pressure Among Patients With Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 700NCT01255436
• Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 193NCT02631850
• Effects of Atorvastatin on Myonecrosis: Complete Statistical AnalysisIndependent statistical analysis of Effects of Atorvastatin on Myonecrosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00344019).Phase 4Results postedn = 97NCT00344019
• Effects of Biofeedback in Patients With Acute Cerebral Infarction: Complete Statistical AnalysisIndependent statistical analysis of Effects of Biofeedback in Patients With Acute Cerebral Infarction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03516227).Phase NAResults postedn = 40NCT03516227
• Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack: Complete Statistical AnalysisIndependent statistical analysis of Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00929994).Phase NAResults postedn = 20NCT00929994
• Effects of Fish Oil on Post Ablation Arrhythmias: Complete Statistical AnalysisIndependent statistical analysis of Effects of Fish Oil on Post Ablation Arrhythmias: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00791089).Phase 4Results postedn = 12NCT00791089
• Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 40NCT00723801
• Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.: Complete Statistical AnalysisIndependent statistical analysis of Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 45NCT00446459
• Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers: Complete Statistical AnalysisIndependent statistical analysis of Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 156NCT01549860
• Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery: Complete Statistical AnalysisIndependent statistical analysis of Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 106NCT00543309
• Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 36NCT00660075
• Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons: Complete Statistical AnalysisIndependent statistical analysis of Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 25NCT00481351
• Effects of the Beta-blocker Nebivolol (Bystolic) on Subjects With High Normal Blood Pressure and/or a Family History of Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Effects of the Beta-blocker Nebivolol (Bystolic) on Subjects With High Normal Blood Pressure and/or a Family History of Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 4Results postedn = 50NCT01202175
• Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.: Complete Statistical AnalysisIndependent statistical analysis of Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase NAResults postedn = 23NCT02693834
• Efficacy and Safety of Azilsartan Medoxomil in African American Participants With Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Azilsartan Medoxomil in African American Participants With Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 413NCT00591253
• Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Nebivolol (Added to Lisinopril or Losartan) in Hypertensive Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 491NCT00734630
• Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 1,183NCT00437645
• Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 885NCT00760214
• Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant Therapy: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant Therapy: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 216NCT00708435
• Efficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE): Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 91NCT00262080
• Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis: Complete Statistical AnalysisIndependent statistical analysis of Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 161NCT02531633
• Efficacy of Aliskiren in the Treatment of Diabetic Macular Edema: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Aliskiren in the Treatment of Diabetic Macular Edema: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00768040).Phase 2Results postedn = 39NCT00768040
• Efficacy of Changing to TRAVATAN® From Prior Therapy: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Changing to TRAVATAN® From Prior Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01510145).Phase 4Results postedn = 191NCT01510145
• Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 22NCT03182582
• Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399): Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 4Results postedn = 334NCT01277822
• Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass: Complete Statistical AnalysisIndependent statistical analysis of Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary Bypass: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 24NCT02151877
• Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD: Complete Statistical AnalysisIndependent statistical analysis of Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 127NCT01617681

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