Endocrinology & Metabolism Clinical Trials

Statistical methods in endocrinology & metabolism trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All endocrinology & metabolism trials

698 results

• “Answers in Hours” A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures: Complete Statistical AnalysisIndependent statistical analysis of "Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 8NCT05523154
• 18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D): Complete Statistical AnalysisIndependent statistical analysis of 18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 822NCT00666458
• 1974Independent statistical analysis of Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 43NCT02777073
• 2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.: Complete Statistical AnalysisIndependent statistical analysis of 2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2/3Results postedn = 146NCT00223977
• 36-month Special Drug Use Surveillance on Frequency of Bone Fractures With Sodium Risedronate 75 mg Tablets: Complete Statistical AnalysisIndependent statistical analysis of 36-month Special Drug Use Surveillance on Frequency of Bone Fractures With Sodium Risedronate 75 mg Tablets: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 579NCT02106442
• 52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period: Complete Statistical AnalysisIndependent statistical analysis of 52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 891NCT00575588
• 6MPIndependent statistical analysis of A Clinical Trial in Patients With Breast Cancer Susceptibility Gene (BRCA) Defective Tumours: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 74NCT01432145
• 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia: Complete Statistical AnalysisIndependent statistical analysis of 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1Results postedn = 39NCT00739999
• 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients: Complete Statistical AnalysisIndependent statistical analysis of 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 4NCT03065218
• A “Real World” Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM): Complete Statistical AnalysisIndependent statistical analysis of A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo (ACHIEVE CONTROL REAL LIFE STUDY PROGRAM): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 4Results postedn = 3,304NCT02451137
• A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY: Complete Statistical AnalysisIndependent statistical analysis of A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY: primary endpoint results,…Phase 2Results postedn = 151NCT04617275
• A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 5NCT00283933
• A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 40NCT01673191
• A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease: Complete Statistical AnalysisIndependent statistical analysis of A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 154NCT01074125
• A Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD): Complete Statistical AnalysisIndependent statistical analysis of A Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 35NCT03852498
• A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 45NCT00660309
• A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 506NCT02420262
• A Clinical Trial of Autologous Oxidized Tumor Cell Lysate Vaccine For Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial of Autologous Oxidized Tumor Cell Lysate Vaccine For Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 1/2Results postedn = 3NCT01312389
• A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 136NCT00830037
• A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384): Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 135NCT02460159
• A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN): Complete Statistical AnalysisIndependent statistical analysis of A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN):…Phase 2Results postedn = 141NCT02215252
• A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters: Complete Statistical AnalysisIndependent statistical analysis of A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 94NCT01196533
• A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 2 Diabetes Mellitus (T2DM): Complete Statistical AnalysisIndependent statistical analysis of A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 2 Diabetes Mellitus (T2DM): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1Results postedn = 36NCT03341312
• A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin: Complete Statistical AnalysisIndependent statistical analysis of A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin: primary endpoint results, effect estimate…Phase 4Results postedn = 255NCT00870194
• A Dose Escalation Safety Study of Locally-Delivered Gemcitabine in Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Dose Escalation Safety Study of Locally-Delivered Gemcitabine in Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 20NCT02237157
• A Dose-Escalation to Rash Study of Tarceva (Erlotinib) Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Dose-Escalation to Rash Study of Tarceva (Erlotinib) Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 467NCT00652366
• A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea: Complete Statistical AnalysisIndependent statistical analysis of A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea:…Phase 3Results postedn = 678NCT01381900
• A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH): Complete Statistical AnalysisIndependent statistical analysis of A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02651675).Phase 1/2Results postedn = 9NCT02651675
• A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 596NCT01847274
• A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women: Complete Statistical AnalysisIndependent statistical analysis of A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 1,335NCT03880461
• A Mobile Phone Based Pilot Intervention to Prevent Obesity in Latino Preschool Children: Complete Statistical AnalysisIndependent statistical analysis of A Mobile Phone Based Pilot Intervention to Prevent Obesity in Latino Preschool Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 59NCT04261985
• A Multicenter Extension Trial to Evaluate the Safety of Testosterone Gel: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter Extension Trial to Evaluate the Safety of Testosterone Gel: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 145NCT01703741
• A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 760NCT00463606
• A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 16NCT03048747
• A Multicenter, Safety and Efficacy Study of Taliglucerase Alfa in Subjects With Type 3 Gaucher Disease: Complete Statistical AnalysisIndependent statistical analysis of A Multicenter, Safety and Efficacy Study of Taliglucerase Alfa in Subjects With Type 3 Gaucher Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 14NCT04002830
• A Multiple Dose Investigational Drug Study in Patients With Type 2 Diabetes (MK-0941-005): Complete Statistical AnalysisIndependent statistical analysis of A Multiple Dose Investigational Drug Study in Patients With Type 2 Diabetes (MK-0941-005): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 70NCT00511667
• A Multiple-ascending-dose Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of MEDI0382 in Overweight and Obese Participants With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Multiple-ascending-dose Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of MEDI0382 in Overweight and Obese Participants With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate…Phase 1/2Results postedn = 113NCT02548585
• A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians: Complete Statistical AnalysisIndependent statistical analysis of A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 207NCT02266576
• A Performance Evaluation of the Enlite Glucose Sensor to Support a Full 144 Hours(6Days) of Use: Complete Statistical AnalysisIndependent statistical analysis of A Performance Evaluation of the Enlite Glucose Sensor to Support a Full 144 Hours(6Days) of Use: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 90NCT01464346
• A Personalized Self-care Support Program for Primary Care Patients With Diabetic Foot Ulcer: Complete Statistical AnalysisIndependent statistical analysis of A Personalized Self-care Support Program for Primary Care Patients With Diabetic Foot Ulcer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 29NCT06540170
• A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen: Complete Statistical AnalysisIndependent statistical analysis of A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1Results postedn = 17NCT00623831
• A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies: Complete Statistical AnalysisIndependent statistical analysis of A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected…Phase 1/2Results postedn = 222NCT03829501
• A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy: primary endpoint…Phase 2Results postedn = 226NCT01712061
• A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05053035).Phase 2Results postedn = 5NCT05053035
• A Phase 2b Diabetic Kidney Disease Study: Complete Statistical AnalysisIndependent statistical analysis of A Phase 2b Diabetic Kidney Disease Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04170543).Phase 2Results postedn = 609NCT04170543
• A Phase 3 Study to Compare Between CT-P41 and US-licensed Prolia in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Phase 3 Study to Compare Between CT-P41 and US-licensed Prolia in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 479NCT04757376
• A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome: primary endpoint results, effect estimate…Phase 4Results postedn = 125NCT00508157
• A Phase 4, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 4, Open-label, Long-term Study of SYR-472 (100 mg) in Combination With Insulin in Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Phase 4, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 4, Open-label, Long-term Study of SYR-472 (100 mg) in Combination With Insulin in Patients With Type 2…Phase 3Results postedn = 240NCT02324569
• A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 6NCT01283035
• A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 4NCT00947167

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