Endocrinology & Metabolism Clinical Trials

Statistical methods in endocrinology & metabolism trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All endocrinology & metabolism trials

1,009 results

• One-Day Acceptance and Commitment Training Intervention in Primary Care Patients: Complete Statistical AnalysisIndependent statistical analysis of One-Day Acceptance and Commitment Training Intervention in Primary Care Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01879800).Phase NAResults postedn = 44NCT01879800
• One-Year Trial of Oral Ziprasidone in Bipolar Patients With Metabolic Syndrome: Complete Statistical AnalysisIndependent statistical analysis of One-Year Trial of Oral Ziprasidone in Bipolar Patients With Metabolic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 13NCT01113541
• onset 9Independent statistical analysis of onset 9, a randomized phase 3 trial comparing faster-acting insulin aspart with NovoRapid in people with type 2 diabetes, including its non-inferiority analysis of HbA1c change.Phase 3Results postedn = 1,264NCT03268005
• onset® 1Complete statistical analysis of the onset® 1 phase 3 trial of faster-acting insulin aspart compared with insulin aspart in adults with type 1 diabetes, including the randomized design, HbA1c endpoint, MMRM methodology,…Phase 3Results postedn = 1,290NCT01831765
• ONTAKIndependent statistical analysis of A Trial of Intravenous Denileukin Diftitox in Stage III or IV Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 19NCT00880360
• OPALINEIndependent statistical analysis of OPALINE : A Study Of Morbidity And Mortality At 2 Years: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 144NCT02264665
• Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese Patients: Complete Statistical AnalysisIndependent statistical analysis of Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 159NCT01190007
• Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD): Complete Statistical AnalysisIndependent statistical analysis of Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 1/2Results postedn = 8NCT05683860
• Open-label Extension Study to Evaluate the Safety of Long-term Twice-monthly Administration of Somavaratan in Adult Growth Hormone Deficiency (AGHD): Complete Statistical AnalysisIndependent statistical analysis of Open-label Extension Study to Evaluate the Safety of Long-term Twice-monthly Administration of Somavaratan in Adult Growth Hormone Deficiency (AGHD): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 36NCT02719990
• Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study: Complete Statistical AnalysisIndependent statistical analysis of Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study: primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 23NCT00526071
• Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.: Complete Statistical AnalysisIndependent statistical analysis of Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.: primary endpoint results, effect…Phase NAResults postedn = 21NCT05827536
• OPT-821 With or Without Vaccine Therapy in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in Second or Third Complete Remission: Complete Statistical AnalysisIndependent statistical analysis of OPT-821 With or Without Vaccine Therapy in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in Second or Third Complete Remission: primary endpoint results,…Phase 2Results postedn = 171NCT00857545
• OPT101 in Type 1 Diabetes Patients: Complete Statistical AnalysisIndependent statistical analysis of OPT101 in Type 1 Diabetes Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05428943).Phase 1Results postedn = 24NCT05428943
• OpT2miseIndependent statistical analysis of OpT2mise Glucose Control in Type 2 Diabetes Mellitus (DM) With Insulin Pump Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 331NCT01182493
• Oral Contraceptives in the Metabolic Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Oral Contraceptives in the Metabolic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00205504).Phase 4Results postedn = 46NCT00205504
• Oral Iron Versus Oral Iron Plus a Web-based Behavioral Intervention in Young Children (IRONCHILD): Complete Statistical AnalysisIndependent statistical analysis of Oral Iron Versus Oral Iron Plus a Web-based Behavioral Intervention in Young Children (IRONCHILD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 1NCT04371536
• Oral Paricalcitol in Kidney Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of Oral Paricalcitol in Kidney Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00587158).Phase NAResults postedn = 100NCT00587158
• Oral Testosterone for the Treatment of Hypogonadism: Complete Statistical AnalysisIndependent statistical analysis of Oral Testosterone for the Treatment of Hypogonadism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01717768).Phase 2Results postedn = 130NCT01717768
• ORANGEIndependent statistical analysis of Oral Amino Acid Nutrition to Improve Glucose Excursions in PCOS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03717935).Phase NAResults postedn = 27NCT03717935
• OReOIndependent statistical analysis of A Study to Examine Olaparib Maintenance Retreatment in Patients With Epithelial Ovarian Cancer.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 220NCT03106987
• ORIGINComplete statistical analysis of the ORIGIN phase 3 trial, including its factorial design, cardiovascular and diabetes endpoints, Cox and log-rank methods, odds ratios, confidence intervals, and statistical interpretation.Phase 3Results postedn = 12,537NCT00069784
• ORION-10Independent statistical analysis of Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 1,561NCT03399370
• OTBB2Independent statistical analysis of Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1/2Results postedn = 18NCT02205034
• Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas: Complete Statistical AnalysisIndependent statistical analysis of Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 32NCT01762059
• Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS: Complete Statistical AnalysisIndependent statistical analysis of Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01909141).Phase EARLY_1Results postedn = 100NCT01909141
• Oxaliplatin, Gemcitabine and Bevacizumab in Women With Recurrent Mullerian Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of Oxaliplatin, Gemcitabine and Bevacizumab in Women With Recurrent Mullerian Carcinoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00418093).Phase 2Results postedn = 19NCT00418093
• Oxidative Stress in Asthma: Complete Statistical AnalysisIndependent statistical analysis of Oxidative Stress in Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04512547).Phase 2Results postedn = 49NCT04512547
• OXT-PWSIndependent statistical analysis of Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 23NCT02629991
• Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients: Complete Statistical AnalysisIndependent statistical analysis of Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 80NCT03021551
• PA 03-103Independent statistical analysis of Controlled Trial of Prenatal Vitamin D3 Supplementation to Prevent Vitamin D Deficiency in Mothers and Their Infants: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 192NCT00610688
• Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 9NCT02923739
• Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors: Complete Statistical AnalysisIndependent statistical analysis of Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors: primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 63NCT01042522
• Paclitaxel in Treating Patients With Ovarian Stromal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Paclitaxel in Treating Patients With Ovarian Stromal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00006227).Phase 2Results postedn = 31NCT00006227
• Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer: primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 108NCT01199263
• Painted Playgrounds: Aim 2: Assessments: Complete Statistical AnalysisIndependent statistical analysis of Painted Playgrounds: Aim 2: Assessments: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03885518).Phase NAResults postedn = 51NCT03885518
• Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food: Complete Statistical AnalysisIndependent statistical analysis of Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to Food: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 65NCT00845871
• PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer: Complete Statistical AnalysisIndependent statistical analysis of PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00088413).Phase 1/2Results postedn = 51NCT00088413
• PASIndependent statistical analysis of Post Approval Study of the Eversense® Continuous Glucose Monitoring: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03908125).Phase NAResults postedn = 273NCT03908125
• Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer: Complete Statistical AnalysisIndependent statistical analysis of Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00625846).Phase 2Results postedn = 152NCT00625846
• PCORI Urea Cycle Disorder Study: Complete Statistical AnalysisIndependent statistical analysis of PCORI Urea Cycle Disorder Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02740153).Phase NAResults postedn = 187NCT02740153
• PCOSIndependent statistical analysis of Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 51NCT00868140
• PDA+Independent statistical analysis of PDA+: A Personal Digital Assistant for Obesity Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00371462).Phase NAResults postedn = 70NCT00371462
• PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction: Complete Statistical AnalysisIndependent statistical analysis of PDE5 Inhibition for Obesity-Related Cardiometabolic Dysfunction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02819440).Phase 2Results postedn = 141NCT02819440
• Peak Impact Forces and Metabolic Cost During Mid-Forefoot Striking in Shod Versus Barefoot Runners: Complete Statistical AnalysisIndependent statistical analysis of Peak Impact Forces and Metabolic Cost During Mid-Forefoot Striking in Shod Versus Barefoot Runners: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase NAResults postedn = 22NCT01536171
• Peer Support Dyads in Churches: Complete Statistical AnalysisIndependent statistical analysis of Peer Support Dyads in Churches: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03463941).Phase NAResults postedn = 80NCT03463941
• Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy: Complete Statistical AnalysisIndependent statistical analysis of Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 11NCT04772313
• PEGRescueIndependent statistical analysis of Prospective Evaluation of NOTES (Natural Orifice Translumenal Endoscopic Surgery) PEG "Rescue": primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 1NCT01119040
• Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer: Complete Statistical AnalysisIndependent statistical analysis of Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer: primary endpoint results, effect estimate…Phase 3Results postedn = 601NCT00807768
• Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 4NCT00310050
• Pen PreferenceIndependent statistical analysis of Patient Preference and Satisfaction With Insulin Glargine (Lantus) Solostar Pen vs Conventional Vial-Syringe Method of Lantus Injection Therapy in Patients With Type 2 Diabetes Mellitus: primary endpoint results,…Phase 4Results postedn = 405NCT01226043

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