Endocrinology & Metabolism Clinical Trials

Statistical methods in endocrinology & metabolism trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All endocrinology & metabolism trials

698 results

• A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma: primary endpoint results, effect estimate with…Phase 2Results postedn = 3NCT05634577
• A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA): Complete Statistical AnalysisIndependent statistical analysis of A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 2,014NCT02694978
• A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1Results postedn = 13NCT02624804
• A Pilot Study on Diurnal Variation: Complete Statistical AnalysisIndependent statistical analysis of A Pilot Study on Diurnal Variation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01806051).Phase NAResults postedn = 6NCT01806051
• A Placebo Controlled Safety and Efficacy Study of MSDC-0160 in Type 2 Diabetes With Active Comparator: Complete Statistical AnalysisIndependent statistical analysis of A Placebo Controlled Safety and Efficacy Study of MSDC-0160 in Type 2 Diabetes With Active Comparator: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 86NCT00760578
• A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves’ Disease: Complete Statistical AnalysisIndependent statistical analysis of A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 32NCT05907668
• A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 30NCT00203476
• A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1: primary endpoint results, effect…Phase NAResults postedn = 13NCT04577183
• A Prospective, Randomized, Double-blind, Placebo Controlled Study to Assess the Impact of ORMD-0801 (Insulin Capsules) on the Exogenous Insulin Requirements of Type 1 Diabetics: Complete Statistical AnalysisIndependent statistical analysis of A Prospective, Randomized, Double-blind, Placebo Controlled Study to Assess the Impact of ORMD-0801 (Insulin Capsules) on the Exogenous Insulin Requirements of Type 1 Diabetics: primary endpoint results, effect…Phase 2Results postedn = 25NCT02094534
• A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 294NCT02016716
• A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 212NCT00306189
• A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America: Complete Statistical AnalysisIndependent statistical analysis of A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 500NCT05579249
• A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type…Phase 3Results postedn = 148NCT05813912
• A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP): Complete Statistical AnalysisIndependent statistical analysis of A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 48NCT01419028
• A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]: Complete Statistical AnalysisIndependent statistical analysis of A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West…Phase NAResults postedn = 50NCT02377947
• A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 4Results postedn = 6NCT00140621
• A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 336NCT03285308
• A Safety and Efficacy Study of VI-0521 to Evaluate the Long Term Treatment of Obesity in Adults With Obesity-Related Co-Morbid Conditions. An Extension Study of Protocol OB-303 (NCT00553787): Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of VI-0521 to Evaluate the Long Term Treatment of Obesity in Adults With Obesity-Related Co-Morbid Conditions. An Extension Study of Protocol OB-303 (NCT00553787):…Phase 3Results postedn = 676NCT00796367
• A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD): Complete Statistical AnalysisIndependent statistical analysis of A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 55NCT00648167
• A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP): Complete Statistical AnalysisIndependent statistical analysis of A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04578496).Phase 3Results postedn = 16NCT04578496
• A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic Amyloidosis: Complete Statistical AnalysisIndependent statistical analysis of A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic Amyloidosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 23NCT02603172
• A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors: Complete Statistical AnalysisIndependent statistical analysis of A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 3Results postedn = 429NCT00186901
• A Single-Dose Crossover Study of MK0893 in Patients With Type 2 Diabetes (0893-019 AM4)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of A Single-Dose Crossover Study of MK0893 in Patients With Type 2 Diabetes (0893-019 AM4)(COMPLETED): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 22NCT00902161
• A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 32NCT01650324
• A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 20NCT02496221
• A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies: Complete Statistical AnalysisIndependent statistical analysis of A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 1/2Results postedn = 52NCT03241173
• A Study for Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study for Patients With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01027871).Phase 2Results postedn = 289NCT01027871
• A Study for the Treatment of Diabetic Peripheral Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of A Study for the Treatment of Diabetic Peripheral Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00552175).Phase 3Results postedn = 339NCT00552175
• A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253): Complete Statistical AnalysisIndependent statistical analysis of A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus…Phase 3Results postedn = 498NCT01590771
• A Study in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria: Complete Statistical AnalysisIndependent statistical analysis of A Study in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 154NCT01847092
• A Study in Participants With Diabetic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study in Participants With Diabetic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01113801).Phase 2Results postedn = 417NCT01113801
• A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): Complete Statistical AnalysisIndependent statistical analysis of A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 421NCT00643760
• A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma: primary endpoint results, effect estimate with confidence interval,…Phase 2Results postedn = 106NCT02981342
• A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044): Complete Statistical AnalysisIndependent statistical analysis of A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 363NCT00127192
• A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 607NCT01214720
• A Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation: Complete Statistical AnalysisIndependent statistical analysis of A Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 13NCT02432690
• A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Bonviva (Ibandronate) and Alendronate on Renal Function in Postmenopausal Women With Osteoporosis at High Risk for Renal Disease.: primary endpoint results, effect estimate with confidence…Phase 4Results postedn = 801NCT00503113
• A Study of Clinical Outcomes of the REALIZE Adjustable Gastric Band-C: Complete Statistical AnalysisIndependent statistical analysis of A Study of Clinical Outcomes of the REALIZE Adjustable Gastric Band-C: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 231NCT00999661
• A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI): Complete Statistical AnalysisIndependent statistical analysis of A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 4Results postedn = 1NCT03859869
• A Study of E7080 in Subjects With Advanced Thyroid Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of E7080 in Subjects With Advanced Thyroid Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01728623).Phase 2Results postedn = 51NCT01728623
• A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158): Complete Statistical AnalysisIndependent statistical analysis of A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 10NCT01583647
• A Study of Liposomal Doxorubicin With or Without Olaratumab (IMC-3G3) in Platinum-Refractory or Resistant Advanced Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Liposomal Doxorubicin With or Without Olaratumab (IMC-3G3) in Platinum-Refractory or Resistant Advanced Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 125NCT00913835
• A Study of LY2189102 in Patients With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY2189102 in Patients With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00942188).Phase 2Results postedn = 106NCT00942188
• A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1Results postedn = 29NCT01408888
• A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 38NCT01029795
• A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 179NCT06124807
• A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related Comorbidities: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related Comorbidities: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 1Results postedn = 24NCT06023095
• A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1Results postedn = 62NCT05086445
• A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 404NCT06074562
• A Study of LY900014 and Insulin Degludec in Participants With Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY900014 and Insulin Degludec in Participants With Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 31NCT04585776

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