Endocrinology & Metabolism Clinical Trials

Statistical methods in endocrinology & metabolism trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All endocrinology & metabolism trials

698 results

• A Study of LY900014 in Participants With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY900014 in Participants With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 38NCT03305822
• A Study of Mobile Medical Supportive Care Program for Family Caregivers With Dementia Combined With Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of Mobile Medical Supportive Care Program for Family Caregivers With Dementia Combined With Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 60NCT06785857
• A Study of MORAb-202 Versus Investigator’s Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer: primary endpoint results, effect estimate…Phase 2Results postedn = 106NCT05613088
• A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1/2Results postedn = 184NCT03086369
• A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia: Complete Statistical AnalysisIndependent statistical analysis of A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia: primary endpoint…Phase 2Results postedn = 154NCT05355402
• A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II): Complete Statistical AnalysisIndependent statistical analysis of A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II): primary endpoint results, effect estimate with confidence…Phase 1/2Results postedn = 136NCT01482715
• A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 138NCT02222922
• A Study Of PF-06664178 In Patients With Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study Of PF-06664178 In Patients With Advanced Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02122146).Phase 1Results postedn = 31NCT02122146
• A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas: Complete Statistical AnalysisIndependent statistical analysis of A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 768NCT00313313
• A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 12NCT02806960
• A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 1,021NCT01239732
• A Study Of The Analgesic (Pain-Relief) Effects Of Tanezumab In Adult Patients With Diabetic Peripheral Neuropathy: Complete Statistical AnalysisIndependent statistical analysis of A Study Of The Analgesic (Pain-Relief) Effects Of Tanezumab In Adult Patients With Diabetic Peripheral Neuropathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 73NCT01087203
• A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 507NCT01098539
• A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary…Phase 3Results postedn = 100NCT03635489
• A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD): primary endpoint results, effect estimate…Phase 2/3Results postedn = 32NCT01896102
• A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 494NCT00168389
• A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM): Complete Statistical AnalysisIndependent statistical analysis of A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 1Results postedn = 142NCT02759107
• A Study of U-500 Insulin (LY041001) in Participants With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of U-500 Insulin (LY041001) in Participants With Type 2 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 1Results postedn = 11NCT02588950
• A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1/2Results postedn = 45NCT00745251
• A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission: Complete Statistical AnalysisIndependent statistical analysis of A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission: primary endpoint results, effect estimate…Phase 2Results postedn = 104NCT00739661
• A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria: Complete Statistical AnalysisIndependent statistical analysis of A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 5NCT00879034
• A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 1Results postedn = 80NCT02637037
• A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular…Phase 3Results postedn = 618NCT00479713
• A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With Late-Onset Pompe Disease (LOPD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With Late-Onset Pompe Disease (LOPD): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 119NCT04138277
• A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 108NCT02993926
• A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing’s Syndrome.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing's Syndrome.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 84NCT03277690
• A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes: primary endpoint results, effect estimate…Phase 2Results postedn = 420NCT02119819
• A Study to Compare Efficacy, PK, PD, Safety and IMM of MB09 to Prolia® [EU-sourced] in Postmenopausal Osteoporosis.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare Efficacy, PK, PD, Safety and IMM of MB09 to Prolia® [EU-sourced] in Postmenopausal Osteoporosis.: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 558NCT05338086
• A Study to Compare SB16 (Proposed Denosumab Biosimilar) to Prolia® in Postmenopausal Women With Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Compare SB16 (Proposed Denosumab Biosimilar) to Prolia® in Postmenopausal Women With Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 457NCT04664959
• A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 7,808NCT00089791
• A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1): primary endpoint results,…Phase NAResults postedn = 93NCT01333436
• A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 29NCT04481243
• A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD): primary endpoint…Phase 3Results postedn = 2NCT04064827
• A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 460NCT03100058
• A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of GLP-1 Drug Semaglutide on Midazolam Blood Levels in Healthy Adults With Weight in the Obesity Range: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of…Phase 1Results postedn = 32NCT05671653
• A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High…Phase 3Results postedn = 406NCT01370590
• A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic…Phase 3Results postedn = 1,186NCT01809327
• A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 1Results postedn = 32NCT03577275
• A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 125NCT04504825
• A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes: primary endpoint results, effect estimate with…Phase 2Results postedn = 834NCT03235050
• A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 25NCT03116685
• A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin:…Phase 4Results postedn = 218NCT02025907
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval,…Phase 1Results postedn = 20NCT04889157
• A Study to Evaluate the Safety and Efficacy of Denosumab and Ibandronate in Postmenopausal Women Sub-Optimally Treated With Daily or Weekly Bisphosphonates: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of Denosumab and Ibandronate in Postmenopausal Women Sub-Optimally Treated With Daily or Weekly Bisphosphonates: primary endpoint results, effect estimate with…Phase 3Results postedn = 833NCT00936897
• A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on…Phase 3Results postedn = 402NCT01755156
• A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 155NCT06019559
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with confidence interval,…Phase 1Results postedn = 37NCT04552470
• A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 toPhase 3Results postedn = 171NCT03170518
• A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich’s Ataxia: Complete Statistical AnalysisIndependent statistical analysis of A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia: primary endpoint results, effect estimate with…Phase 2Results postedn = 172NCT02255435
• A Study to Test How Well Empagliflozin Works in Chinese Patients With Type 2 Diabetes Who Already Take Insulin: Complete Statistical AnalysisIndependent statistical analysis of A Study to Test How Well Empagliflozin Works in Chinese Patients With Type 2 Diabetes Who Already Take Insulin: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 219NCT04233801

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