Endocrinology & Metabolism Clinical Trials

Statistical methods in endocrinology & metabolism trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All endocrinology & metabolism trials

698 results

• A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 332NCT04729621
• A Study to Test MK-0941 in Adults With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0941-018): Complete Statistical AnalysisIndependent statistical analysis of A Study to Test MK-0941 in Adults With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0941-018): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 68NCT00824616
• A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes: Complete Statistical AnalysisIndependent statistical analysis of A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes: primary…Phase NAResults postedn = 26,774NCT03993132
• A Sugar-Sweetened Beverage Reduction Intervention for Native American Men: Complete Statistical AnalysisIndependent statistical analysis of A Sugar-Sweetened Beverage Reduction Intervention for Native American Men: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06029517).Phase NAResults postedn = 48NCT06029517
• A to ZAn independent statistical analysis of the A to Z study follow-up for DNA data collection from buccal swabs, focusing on genotype-diet interaction and changes in weight, body fat, and BMI.n = 150NCT00866151
• A Trial Comparing Ferumoxytol With Placebo for the Treatment of Iron Deficiency Anemia: Complete Statistical AnalysisIndependent statistical analysis of A Trial Comparing Ferumoxytol With Placebo for the Treatment of Iron Deficiency Anemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 3Results postedn = 812NCT01114139
• A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus.: Complete Statistical AnalysisIndependent statistical analysis of A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus.: primary endpoint results, effect estimate…Phase 3Results postedn = 635NCT02505334
• A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus…Phase 3Results postedn = 362NCT01835431
• A Trial of FANG™ Vaccine for Participants With Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Trial of FANG™ Vaccine for Participants With Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01309230).Phase 2Results postedn = 39NCT01309230
• A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 634NCT01114217
• A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable…Phase 2Results postedn = 241NCT02702388
• A Trial of Two Family-based Childhood Obesity Treatment Programs: Complete Statistical AnalysisIndependent statistical analysis of A Trial of Two Family-based Childhood Obesity Treatment Programs: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03245775).Phase NAResults postedn = 267NCT03245775
• A Trial To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Single Doses Of PF-04937319 In Subjects With Type 2 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Trial To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Single Doses Of PF-04937319 In Subjects With Type 2 Diabetes Mellitus: primary endpoint results, effect estimate with…Phase 1Results postedn = 50NCT01044537
• A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects: primary endpoint results, effect estimate with confidence interval,…Phase 3Results postedn = 170NCT03378635
• A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin: Complete Statistical AnalysisIndependent statistical analysis of A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 688NCT00386100
• A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program: Complete Statistical AnalysisIndependent statistical analysis of A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 60NCT05144737
• AAAA2Independent statistical analysis of Activity, Adiposity, and Appetite in Adolescents 2: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04028921).Phase NAResults postedn = 46NCT04028921
• AAAA2INTIndependent statistical analysis of Activity, Adiposity, and Appetite in Adolescents 2 Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05443347).Phase NAResults postedn = 31NCT05443347
• Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease: Complete Statistical AnalysisIndependent statistical analysis of Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 1Results postedn = 8NCT01835496
• Acupressure for Fatigue in Ovarian Cancer Survivors: Complete Statistical AnalysisIndependent statistical analysis of Acupressure for Fatigue in Ovarian Cancer Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03763838).Phase NAResults postedn = 171NCT03763838
• Acute Exercise Effects in Obese Pregnancy: Complete Statistical AnalysisIndependent statistical analysis of Acute Exercise Effects in Obese Pregnancy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03750695).Phase NAResults postedn = 16NCT03750695
• Adding Guided Self-Help Group Therapy to the Alli Weight Loss Program in Treating Binge Eating Disorder: Complete Statistical AnalysisIndependent statistical analysis of Adding Guided Self-Help Group Therapy to the Alli Weight Loss Program in Treating Binge Eating Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 17NCT00601354
• Addressing Social Determinants of Health & Diabetes Self-Management in Vulnerable Populations: Complete Statistical AnalysisIndependent statistical analysis of Addressing Social Determinants of Health & Diabetes Self-Management in Vulnerable Populations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase NAResults postedn = 110NCT03802825
• Adherence and Intensification of Medications (AIM) Implementation Study: Complete Statistical AnalysisIndependent statistical analysis of Adherence and Intensification of Medications (AIM) Implementation Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00495794).Phase NAResults postedn = 4,622NCT00495794
• ADJUNCT ONE™Complete statistical analysis of the phase 3 ADJUNCT ONE™ trial of liraglutide as adjunct therapy to insulin in type 1 diabetes, including non-inferiority analysis of HbA1c, body-weight and insulin-dose results, hypoglycemia, methodology,…Phase 3Results postedn = 1,398NCT01836523
• Administration of IV Laronidase Post Bone Marrow Transplant in Hurler: Complete Statistical AnalysisIndependent statistical analysis of Administration of IV Laronidase Post Bone Marrow Transplant in Hurler: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01173016).Phase 1Results postedn = 11NCT01173016
• Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa: Complete Statistical AnalysisIndependent statistical analysis of Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00310791).Phase 2/3Results postedn = 80NCT00310791
• ADVANCEIndependent statistical analysis of the ADVANCE phase 3 trial of blood pressure and glucose lowering for prevention of vascular disease in high-risk patients with type 2 diabetes, including its factorial design, composite…Phase 3n = 11,140NCT00145925
• AIDAIndependent statistical analysis of Adjusting Insulin Delivery to Activity: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02299479).Phase NAResults postedn = 20NCT02299479
• ALFSG-MBTIndependent statistical analysis of 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2/3Results postedn = 76NCT02786836
• Alimta® Plus Cisplatin & Paclitaxel Given Intraperitonelly; First Line Tx Stage III Ovarian Cancer: Complete Statistical AnalysisIndependent statistical analysis of Alimta® Plus Cisplatin & Paclitaxel Given Intraperitonelly; First Line Tx Stage III Ovarian Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 1Results postedn = 15NCT00702299
• Alisertib (MLN8237) in Participants With Ovarian, Fallopian Tube or Peritoneal Cancer Preceded by Phase 1 Study of MLN8237 Plus Paclitaxel Treatment of Ovary or Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Alisertib (MLN8237) in Participants With Ovarian, Fallopian Tube or Peritoneal Cancer Preceded by Phase 1 Study of MLN8237 Plus Paclitaxel Treatment of Ovary or Breast Cancer: primary endpoint…Phase 2Results postedn = 191NCT01091428
• Alkali Therapy in Chronic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of Alkali Therapy in Chronic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01452412).Phase 2/3Results postedn = 149NCT01452412
• ALLIndependent statistical analysis of Dissemination of CVD Risk Factor Treatment Among Diabetic Patients in Safety Net Clinics: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 4,856NCT02299791
• ALLAYIndependent statistical analysis of Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 460NCT00219141
• ALLHATA detailed statistical analysis of ALLHAT, the randomized phase 3 Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial, including trial design, endpoints, planned statistical analysis, interpretation, and limitations.Phase 3NCT00000542
• Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid Tumor: Complete Statistical AnalysisIndependent statistical analysis of Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid Tumor: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 5NCT00523809
• Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 13NCT01105650
• ALPHA Sitagliptin Add on to Metformin (0431-103): Complete Statistical AnalysisIndependent statistical analysis of ALPHA Sitagliptin Add on to Metformin (0431-103): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00833027).Phase 4Results postedn = 608NCT00833027
• AMADIndependent statistical analysis of Efficacy of Acupuncture in Macular Diseases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02255981).Phase NAResults postedn = 33NCT02255981
• AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer: Complete Statistical AnalysisIndependent statistical analysis of AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 23NCT00574951
• AMILORIndependent statistical analysis of Amiloride in Nephrotic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05079789).Phase 3Results postedn = 20NCT05079789
• AMPLIFY-201Independent statistical analysis of A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1Results postedn = 25NCT04853017
• AMPLITUDE-OIndependent statistical analysis of the phase 3 AMPLITUDE-O trial of efpeglenatide in people with type 2 diabetes, including randomized design, time-to-event endpoints, non-inferiority and superiority analyses, hazard ratios, confidence intervals, and statistical…Phase 3Results postedn = 4,076NCT03496298
• An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 18NCT03510715
• An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 86NCT01453049
• An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 101NCT01574326
• An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase NAResults postedn = 70NCT02962492
• An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024): Complete Statistical AnalysisIndependent statistical analysis of An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 1,172NCT00094770
• An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 23NCT04538989

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