Gastroenterology & Hepatology Clinical Trials

Statistical methods in gastroenterology & hepatology trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All gastroenterology & hepatology trials

455 results

• A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Japanese Participants With Eosinophilic Gastroenteritis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Japanese Participants With Eosinophilic Gastroenteritis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 48NCT05214768
• A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR…Phase 3Results postedn = 168NCT02516410
• A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults: primary endpoint results, effect estimate…Phase 2Results postedn = 71NCT03527173
• A Study to Evaluate the Efficiency of Intravenously Administered Cyclosporine in de Novo Liver Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficiency of Intravenously Administered Cyclosporine in de Novo Liver Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 34NCT00332462
• A Study to Evaluate the Pharmacokinetic Effect of SCH 503034 (Boceprevir) on Methadone or Buprenorphine/Naloxone Plasma Concentrations (P08123): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Pharmacokinetic Effect of SCH 503034 (Boceprevir) on Methadone or Buprenorphine/Naloxone Plasma Concentrations (P08123): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 1Results postedn = 21NCT01396005
• A Study to Evaluate the Safety and Efficacy of Ustekinumab Maintenance Therapy in Patients With Moderately to Severely Active Crohn’s Disease (IM-UNITI): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of Ustekinumab Maintenance Therapy in Patients With Moderately to Severely Active Crohn's Disease (IM-UNITI): primary endpoint results, effect estimate with…Phase 3Results postedn = 1,282NCT01369355
• A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors: primary endpoint results, effect estimate with…Phase 1/2Results postedn = 5NCT03361228
• A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection: primary endpoint results, effect estimate…Phase 1Results postedn = 60NCT05763576
• A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer: primary endpoint…Phase 1/2Results postedn = 111NCT03941873
• A Study to Investigate the Pharmacokinetic Interactions Between Simeprevir and Ledipasvir in a Treatment Regimen Consisting of Simeprevir, Sofosbuvir, and Ledipasvir in Treatment-naive Participants With Chronic Hepatitis C Virus Genotype 1 Infection: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Pharmacokinetic Interactions Between Simeprevir and Ledipasvir in a Treatment Regimen Consisting of Simeprevir, Sofosbuvir, and Ledipasvir in Treatment-naive Participants With Chronic Hepatitis C…Phase 2Results postedn = 41NCT02421211
• A Study To Investigate The Safety And Efficacy Of CP- 690,550 In Patients With Moderate And Severe Ulcerative Colitis.: Complete Statistical AnalysisIndependent statistical analysis of A Study To Investigate The Safety And Efficacy Of CP- 690,550 In Patients With Moderate And Severe Ulcerative Colitis.: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 195NCT00787202
• A Study to Investigate the Safety and Efficacy of CP-690,550 in Patients With Moderate to Severe Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Safety and Efficacy of CP-690,550 in Patients With Moderate to Severe Crohn's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 139NCT00615199
• A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems: Complete Statistical AnalysisIndependent statistical analysis of A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems: primary endpoint results, effect estimate with confidence interval,…Phase 1Results postedn = 28NCT05661344
• A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of Advanced Hepatocellular Carcinoma (HCC): Complete Statistical AnalysisIndependent statistical analysis of A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of…Phase 1/2Results postedn = 14NCT03071094
• Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis: Complete Statistical AnalysisIndependent statistical analysis of Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 4Results postedn = 759NCT01124149
• Accupressure of P6 to Reduce Nausea During Cesarean Section: Complete Statistical AnalysisIndependent statistical analysis of Accupressure of P6 to Reduce Nausea During Cesarean Section: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04799587).Phase NAResults postedn = 200NCT04799587
• Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy: Complete Statistical AnalysisIndependent statistical analysis of Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 34NCT02123511
• ACTIVATEIndependent statistical analysis of A Collaborative Trial in Injectors of Individualized Treatment for Genotype 2/3: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 93NCT01364090
• AdaProQuoIndependent statistical analysis of Fecal Calprotectin Levels, Quality of Life, and Workability in Patients Suffering From Ulcerative Colitis Under Adalimumab Therapy - AdaProQuo: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 10NCT02092389
• Adefovir Dipivoxil In Compensated Chronic Hepatitis B Patients: Complete Statistical AnalysisIndependent statistical analysis of Adefovir Dipivoxil In Compensated Chronic Hepatitis B Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00316719).Phase 3Results postedn = 105NCT00316719
• Adherence in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C in Conjunction With a Patient Assistance Program (Study P04281)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of Adherence in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C in Conjunction With a Patient Assistance Program (Study P04281)(COMPLETED): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase NAResults postedn = 601NCT00704522
• Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 2Results postedn = 56NCT01652196
• AGATE-1Independent statistical analysis of A Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir Co-administered With Ribavirin (RBV) in Adults With Genotype 4 Chronic Hepatitis C Virus (HCV) Infection and…Phase 3Results postedn = 184NCT02265237
• AHIndependent statistical analysis of A Research Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DUR-928 in Patients With Alcoholic Hepatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 19NCT03432260
• ALFSG-MBTIndependent statistical analysis of 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2/3Results postedn = 76NCT02786836
• Alpha-1 Carrier Genomics Study: Complete Statistical AnalysisIndependent statistical analysis of Alpha-1 Carrier Genomics Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02810327).Phase NAResults postedn = 117NCT02810327
• AMPLIFY-201Independent statistical analysis of A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1Results postedn = 25NCT04853017
• An Efficacy and Safety Study of Ivacaftor in Patients With Cystic Fibrosis and Two Splicing Mutations: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Ivacaftor in Patients With Cystic Fibrosis and Two Splicing Mutations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 2NCT02934698
• An Efficacy and Safety Study of Sonazoid™ and SonoVue® in Participants With Focal Liver Lesions, Undergoing Pre- and Post-Contrast Ultrasound Imaging: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Sonazoid™ and SonoVue® in Participants With Focal Liver Lesions, Undergoing Pre- and Post-Contrast Ultrasound Imaging: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 424NCT03335566
• An Efficacy, Pharmacokinetics, Safety and Tolerability Study of TMC435 as Part of a Treatment Regimen for Hepatitis C-Infected Patients: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy, Pharmacokinetics, Safety and Tolerability Study of TMC435 as Part of a Treatment Regimen for Hepatitis C-Infected Patients: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 457NCT01725529
• An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.: Complete Statistical AnalysisIndependent statistical analysis of An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 1Results postedn = 3NCT03029988
• An Exploratory Study of Telaprevir in Treatment-Naive Participants With Chronic Genotype 4 Hepatitis C Virus Infection: Complete Statistical AnalysisIndependent statistical analysis of An Exploratory Study of Telaprevir in Treatment-Naive Participants With Chronic Genotype 4 Hepatitis C Virus Infection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 24NCT00580801
• An Extension Study to Evaluate the Long-Term Safety and Tolerability of UTTR1147A in Participants With Moderate to Severe Ulcerative Colitis or Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study to Evaluate the Long-Term Safety and Tolerability of UTTR1147A in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease: primary endpoint results, effect estimate…Phase 2Results postedn = 143NCT03650413
• An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys: Complete Statistical AnalysisIndependent statistical analysis of An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 1,842NCT01011738
• An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer: Complete Statistical AnalysisIndependent statistical analysis of An Observational Study of Bevacizumab in Combination With 5-FU-Based Chemotherapy in Chinese Participants With Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase NAResults postedn = 609NCT01319877
• An Observational Study on the Natural Course of Chronic Pancreatitis: Complete Statistical AnalysisIndependent statistical analysis of An Observational Study on the Natural Course of Chronic Pancreatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04574297).Phase NAResults postedn = 798NCT04574297
• An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn’s Disease: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 7NCT01009281
• An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 23NCT04538989
• Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV: Complete Statistical AnalysisIndependent statistical analysis of Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase NAResults postedn = 276NCT01946139
• ANCHOR-CRCIndependent statistical analysis of Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 2Results postedn = 95NCT03693170
• ANGELIndependent statistical analysis of A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer: primary endpoint results, effect estimate with confidence…Phase 3Results postedn = 460NCT03042611
• Anti-LPS Antibody Treatment for Pediatric NAFLD: Complete Statistical AnalysisIndependent statistical analysis of Anti-LPS Antibody Treatment for Pediatric NAFLD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03042767).Phase 2Results postedn = 40NCT03042767
• APEGINIndependent statistical analysis of Evaluation of Rapid Virologic Response Among HCV Patients Treated With PegIntron and Rebetol in Brazil (Study P05427): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase NAResults postedn = 1,146NCT00724854
• APPACIndependent statistical analysis of Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01022567).Phase NAResults postedn = 530NCT01022567
• APPRISE 1Independent statistical analysis of Adenocarcinoma of the Pancreas Treated With Panitumumab and Gemcitabine Regimen to Investigate Overall Survival as Primary Endpoint: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 3NCT00613730
• ASCENTIndependent statistical analysis of A Translational Study of Bevacizumab in Participants With Metastatic Colorectal Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 4Results postedn = 128NCT01588990
• Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation: Complete Statistical AnalysisIndependent statistical analysis of Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 21NCT02521285
• Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion: Complete Statistical AnalysisIndependent statistical analysis of Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase NAResults postedn = 359NCT03598166
• Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca: Complete Statistical AnalysisIndependent statistical analysis of Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 11NCT01555489
• Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin: Complete Statistical AnalysisIndependent statistical analysis of Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase NAResults postedn = 20NCT02552966

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