Statistical methods in immunology & rheumatology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Odds ratio
Multiple imputation / missing data
Cochran-Mantel-Haenszel test
Mixed-effects model
Logistic regression
MMRM (mixed model for repeated measures)
Risk difference
All immunology & rheumatology trials
727 results
- A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of CellCept (Mycophenolate Mofetil) Combined With Tacrolimus and Corticosteroids in Kidney Transplant Patients.: Complete Statistical AnalysisIndependent statistical analysis of A Study of CellCept (Mycophenolate Mofetil) Combined With Tacrolimus and Corticosteroids in Kidney Transplant Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.: Complete Statistical AnalysisIndependent statistical analysis of A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.: Complete Statistical AnalysisIndependent statistical analysis of A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis: primary endpoint results, effect estimate with confidence…
- A Study of DS-7011a in Patients With Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of DS-7011a in Patients With Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05638802).
- A Study of Enfuvirtide (Fuzeon) in Participants With Advanced Human Immunodeficiency Virus (HIV) Infection: Complete Statistical AnalysisIndependent statistical analysis of A Study of Enfuvirtide (Fuzeon) in Participants With Advanced Human Immunodeficiency Virus (HIV) Infection: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis: primary endpoint results, effect estimate with confidence interval,…
- A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy: Complete Statistical AnalysisIndependent statistical analysis of A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy: primary endpoint results, effect estimate with confidence…
- A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH): Complete Statistical AnalysisIndependent statistical analysis of A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH): primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Arthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of LY2439821 in Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY2439821 in Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01236118).
- A Study of LY3039478 in Participants With Advanced Cancer: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3039478 in Participants With Advanced Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01695005).
- A Study of LY900014 and Insulin Degludec in Participants With Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY900014 and Insulin Degludec in Participants With Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin’s Lymphoma (NHL): Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin's Lymphoma (NHL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a TNF-Blocker.: Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a TNF-Blocker.: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma: primary endpoint results, effect estimate with confidence…
- A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Mycophenolate Mofetil (CellCept) in Lung Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study of Mycophenolate Mofetil (CellCept) in Lung Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01014442).
- A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax…
- A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin’s Lymphoma Grades 1, 2 or 3a: Complete Statistical AnalysisIndependent statistical analysis of A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a:…
- A Study of Patients Who Received Inotuzumab Ozogamicin for B-cell ALL (Acute Lymphoblastic Leukemia) That Occurred Again After the Last Treatment: Complete Statistical AnalysisIndependent statistical analysis of A Study of Patients Who Received Inotuzumab Ozogamicin for B-cell ALL (Acute Lymphoblastic Leukemia) That Occurred Again After the Last Treatment: primary endpoint results, effect estimate with confidence…
- A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin’s Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68): Complete Statistical AnalysisIndependent statistical analysis of A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68): primary endpoint results, effect…
- A Study Of Pharmacokinetics, Whole Body And Organ Dosimetry, And Biodistribution Of Fission-Derived Iodine I 131 Tositumomab (BEXXAR®) For Patients With Previously Untreated Or Relapsed Follicular Or Transformed Non-Hodgkin’s Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study Of Pharmacokinetics, Whole Body And Organ Dosimetry, And Biodistribution Of Fission-Derived Iodine I 131 Tositumomab (BEXXAR®) For Patients With Previously Untreated Or Relapsed Follicular Or Transformed…
- A Study of PRCL-02 in Moderate to Severe Chronic Plaque Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of A Study of PRCL-02 in Moderate to Severe Chronic Plaque Psoriasis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL): Complete Statistical AnalysisIndependent statistical analysis of A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF: Complete Statistical AnalysisIndependent statistical analysis of A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Bruton’s Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD): primary endpoint results, effect estimate with confidence…
- A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That is Not Controlled by High Dose Inhaled Corticosteroid Asthma Medications: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That…
- A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy: primary…
- A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.: primary endpoint…
- A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01390441).
- A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate…
- A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size…
- A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma: primary endpoint…
- A Study of the Safety, Tolerability, and Antiretroviral Activity of Raltegravir (MK-0518) in Combination With Other Antiretroviral Therapies in Russian Children and Adolescents Infected With Human Immunodeficiency Virus (HIV-1) (MK-0518-248): Complete Statistical AnalysisIndependent statistical analysis of A Study of the Safety, Tolerability, and Antiretroviral Activity of Raltegravir (MK-0518) in Combination With Other Antiretroviral Therapies in Russian Children and Adolescents Infected With Human Immunodeficiency Virus…
- A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning…