Immunology & Rheumatology Clinical Trials

Statistical methods in immunology & rheumatology trials

The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.

All immunology & rheumatology trials

727 results

• A Study of Tocilizumab in Combination With DMARD Therapy in Patients With Active Rheumatoid Arthritis.: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tocilizumab in Combination With DMARD Therapy in Patients With Active Rheumatoid Arthritis.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 3Results postedn = 209NCT00773461
• A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs): Complete Statistical AnalysisIndependent statistical analysis of A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying…Phase 3Results postedn = 886NCT00891020
• A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs: Complete Statistical AnalysisIndependent statistical analysis of A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 14NCT00810277
• A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…Phase 3Results postedn = 753NCT00296504
• A Study to Assess Immune Response in Pediatric Kidney Transplant Recipients Treated With Daclizumab (Zenapax): Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess Immune Response in Pediatric Kidney Transplant Recipients Treated With Daclizumab (Zenapax): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 4Results postedn = 11NCT02576145
• A Study to Assess the Efficacy, Safety and Tolerability of IRL201104 in Adults With Active Eosinophilic Esophagitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Efficacy, Safety and Tolerability of IRL201104 in Adults With Active Eosinophilic Esophagitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 36NCT05084963
• A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic Diseases: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 58NCT03858634
• A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 718NCT04391894
• A Study to Determine the Efficacy of ZPL-3893787 in Subjects With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Determine the Efficacy of ZPL-3893787 in Subjects With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 98NCT02424253
• A Study to Determine the Immunogenicity and Oral Tolerance to Keyhole Limpet Hemocyanin (KLH): Complete Statistical AnalysisIndependent statistical analysis of A Study to Determine the Immunogenicity and Oral Tolerance to Keyhole Limpet Hemocyanin (KLH): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase EARLY_1Results postedn = 19NCT01489956
• A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 1/2Results postedn = 53NCT02795832
• A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…Phase 2Results postedn = 123NCT02316106
• A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency: primary endpoint results, effect estimate with confidence interval,…Phase 4Results postedn = 33NCT04566692
• A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 4Results postedn = 29NCT04481243
• A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Rituximab (MabThera/Rituxan) in Participants With Diffuse Large B Cell Lymphoma (DLBCL) or Follicular Lymphoma (FL): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Rituximab (MabThera/Rituxan) in Participants With Diffuse Large B Cell Lymphoma (DLBCL) or Follicular Lymphoma (FL): primary endpoint results, effect…Phase 3Results postedn = 159NCT01889069
• A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Anti-pruritic Effectiveness of ASN008 in Adults With Mild to Moderate Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 2Results postedn = 144NCT05870865
• A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of a Single-Dose Intravenous Administration of MEDI-528: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 2Results postedn = 11NCT00483041
• A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 4Results postedn = 79NCT01597492
• A Study to Evaluate the Effectiveness and Safety of SKI-O-703 in Patients Experiencing Active Rheumatoid Arthritis Despite Treatment With Conventional Therapies.: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effectiveness and Safety of SKI-O-703 in Patients Experiencing Active Rheumatoid Arthritis Despite Treatment With Conventional Therapies.: primary endpoint results, effect estimate with confidence…Phase 2Results postedn = 163NCT04057118
• A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 102NCT02545868
• A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor: primary endpoint results,…Phase 2Results postedn = 150NCT01974206
• A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES): primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 125NCT04504825
• A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 2Results postedn = 834NCT01283139
• A Study to Evaluate the Efficacy of Sativex in Relieving Symptoms of Spasticity Due to Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy of Sativex in Relieving Symptoms of Spasticity Due to Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…Phase 3Results postedn = 337NCT01599234
• A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine…Phase 3Results postedn = 323NCT01292473
• A Study to Evaluate the Efficiency of Intravenously Administered Cyclosporine in de Novo Liver Transplant Recipients: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Efficiency of Intravenously Administered Cyclosporine in de Novo Liver Transplant Recipients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 4Results postedn = 34NCT00332462
• A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Long-Term Safety of MEDI-545 in Adult Participants With Systemic Lupus Erythematosus or Myositis: primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 2Results postedn = 118NCT00979654
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).: primary endpoint results, effect estimate with confidence interval,…Phase 1Results postedn = 24NCT03923738
• A Study to Evaluate the Safe and Effective Use of a Zilucoplan Auto-injector by Study Participants With Generalized Myasthenia Gravis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safe and Effective Use of a Zilucoplan Auto-injector by Study Participants With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval,…Phase 3Results postedn = 31NCT06471361
• A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…Phase 4Results postedn = 20NCT00914966
• A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 581NCT00712920
• A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 506NCT00824473
• A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 173NCT00955279
• A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 2Results postedn = 307NCT03011892
• A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD): primary endpoint results, effect estimate with confidence interval, sample-size planning…Phase 3Results postedn = 119NCT04660539
• A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee: Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee: primary endpoint results, effect estimate…Phase 2Results postedn = 389NCT02068599
• A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 69NCT01673620
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): Complete Statistical AnalysisIndependent statistical analysis of A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED): primary endpoint results, effect estimate with…Phase 1Results postedn = 46NCT00636207
• A Study To Investigate And Describe The Treatment Patterns And Effect Of Tofacitinib Indicators For Patients With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study To Investigate And Describe The Treatment Patterns And Effect Of Tofacitinib Indicators For Patients With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase NAResults postedn = 1,712NCT04721808
• A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…Phase 2Results postedn = 44NCT02683785
• A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody: primary…Phase 2Results postedn = 221NCT03525678
• A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval, sample-size…Phase 3Results postedn = 71NCT04124965
• A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin’s Lymphomas, Solid Tumors and Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas,…Phase 1Results postedn = 41NCT02082977
• A Study to Investigate Zanubrutinib in Chinese Participants With B-cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Study to Investigate Zanubrutinib in Chinese Participants With B-cell Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 1Results postedn = 44NCT03189524
• A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: Complete Statistical AnalysisIndependent statistical analysis of A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…Phase 3Results postedn = 200NCT03971422
• A Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs): Complete Statistical AnalysisIndependent statistical analysis of A Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic…Phase 3Results postedn = 338NCT02955212
• A Teleheath tDCS Approach to Decrease Cannabis Use: Complete Statistical AnalysisIndependent statistical analysis of A Teleheath tDCS Approach to Decrease Cannabis Use: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05005013).Phase 2Results postedn = 52NCT05005013
• A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus Meal Time Insulin Aspart in Children and Adolescents With Type 1 Diabetes Mellitus: Complete Statistical AnalysisIndependent statistical analysis of A Trial Investigating the Efficacy and Safety of Insulin Degludec/Insulin Aspart Once Daily Plus Insulin Aspart for the Remaining Meals Versus Insulin Detemir Once or Twice Daily Plus…Phase 3Results postedn = 362NCT01835431
• A Trial of E7777 in Persistent and Recurrent Cutaneous T-Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of A Trial of E7777 in Persistent and Recurrent Cutaneous T-Cell Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…Phase 3Results postedn = 112NCT01871727
• A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects: Complete Statistical AnalysisIndependent statistical analysis of A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects: primary endpoint results, effect estimate with confidence interval,…Phase 3Results postedn = 170NCT03378635

← All therapeutic areas