Statistical methods in immunology & rheumatology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Odds ratio
Multiple imputation / missing data
Cochran-Mantel-Haenszel test
Mixed-effects model
Logistic regression
MMRM (mixed model for repeated measures)
Risk difference
All immunology & rheumatology trials
727 results
- Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu’s Arteritis: Complete Statistical AnalysisIndependent statistical analysis of Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Abatacept in Treating Adults With Mild Relapsing Wegener’s Granulomatosis: Complete Statistical AnalysisIndependent statistical analysis of Abatacept in Treating Adults With Mild Relapsing Wegener's Granulomatosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00468208).
- AC-170Independent statistical analysis of Efficacy of AC-170 for the Treatment of Allergic Conjunctivitis in the Conjunctival Allergen Challenge (CAC) Model: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- ACTH Gel Therapy in Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of ACTH Gel Therapy in Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02030028).
- ACTHARIndependent statistical analysis of Effects of ACTHAR on Advanced MRI Surrogate Markers of Disease Activity and on Comprehensive Immune Signature During MS Relapses: primary endpoint results, effect estimate with confidence interval, sample-size…
- Acthar Gel for Active Systemic Lupus Erythematosus (SLE): Complete Statistical AnalysisIndependent statistical analysis of Acthar Gel for Active Systemic Lupus Erythematosus (SLE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02953821).
- Acupressure in Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of Acupressure in Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05412121).
- Acyclovir to Treat Patients Co-infected With HIV and Herpes Viruses in Uganda: Complete Statistical AnalysisIndependent statistical analysis of Acyclovir to Treat Patients Co-infected With HIV and Herpes Viruses in Uganda: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- ADAPTSC+Independent statistical analysis of Evaluating the Long-Term Safety and Tolerability of Efgartigimod PH20 SC Administered Subcutaneously in Patients With Generalized Myasthenia Gravis: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Addressing the Continuum of Care Among High-risk Thai Men: Complete Statistical AnalysisIndependent statistical analysis of Addressing the Continuum of Care Among High-risk Thai Men: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05161689).
- ADHANDIndependent statistical analysis of A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy: primary endpoint results, effect…
- Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Adipose-derived SVF for the Treatment of Knee OA: Complete Statistical AnalysisIndependent statistical analysis of Adipose-derived SVF for the Treatment of Knee OA: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02726945).
- ADJUNCT ONE™Complete statistical analysis of the phase 3 ADJUNCT ONE™ trial of liraglutide as adjunct therapy to insulin in type 1 diabetes, including non-inferiority analysis of HbA1c, body-weight and insulin-dose results, hypoglycemia, methodology,…
- Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase) in Elderly Patients With First Line Acute Lymphoblastic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase) in Elderly Patients With First Line Acute Lymphoblastic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- ADmIReIndependent statistical analysis of A Study of LY3375880 in Adults With Moderate-to-Severe Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03831191).
- Adrenal Suppression and Pharmacokinetics of Topicort® Spray, 0.25% in Pediatric Patients With Plaque Psoriasis: Complete Statistical AnalysisIndependent statistical analysis of Adrenal Suppression and Pharmacokinetics of Topicort® Spray, 0.25% in Pediatric Patients With Plaque Psoriasis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- ADVANCEIndependent statistical analysis of the phase 3 ADVANCE trial of peginterferon beta-1a versus placebo in relapsing multiple sclerosis, covering negative binomial rate ratios for annualized relapse rate, Cox hazard ratios, lesion mean…
- ADvantageIndependent statistical analysis of A Study of Lebrikizumab in Combination With Topical Corticosteroids in Patients With Atopic Dermatitis (AD) That Are Not Adequately Controlled With or Are Non-eligible for Cyclosporine: primary endpoint…
- ADVISEIndependent statistical analysis of A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Aflibercept for Relapsed Multiple Myeloma: Complete Statistical AnalysisIndependent statistical analysis of Aflibercept for Relapsed Multiple Myeloma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00437034).
- AGAVE-201Independent statistical analysis of A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- AGN-229666 Ophthalmic Solution in Japanese Patients With Allergic Conjunctivitis: Complete Statistical AnalysisIndependent statistical analysis of AGN-229666 Ophthalmic Solution in Japanese Patients With Allergic Conjunctivitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02161146).
- AHEADIndependent statistical analysis of the randomized phase 3 AHEAD trial comparing budesonide/formoterol Turbuhaler with salmeterol/fluticasone Diskus and terbutaline in asthma, including trial design, endpoints, planned statistical analysis, and interpretation.
- AIRSIndependent statistical analysis of A Survey of Adults and Children With Allergic Rhinoconjunctivitis (MK-7243-021): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01535118).
- Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease: Complete Statistical AnalysisIndependent statistical analysis of Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01226420).
- Alemtuzumab + Rituximab Consolidation in CLL: Complete Statistical AnalysisIndependent statistical analysis of Alemtuzumab + Rituximab Consolidation in CLL: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00771602).
- Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01361711).
- Allogeneic Stem Cell Transplant for CLL: Complete Statistical AnalysisIndependent statistical analysis of Allogeneic Stem Cell Transplant for CLL: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01629511).
- AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders: Complete Statistical AnalysisIndependent statistical analysis of AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia: Complete Statistical AnalysisIndependent statistical analysis of AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia: primary endpoint results, effect estimate…
- An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect: Complete Statistical AnalysisIndependent statistical analysis of An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy: Complete Statistical AnalysisIndependent statistical analysis of An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy: primary endpoint results, effect estimate with confidence interval, sample-size…
- An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Proof of Concept Study of Daratumumab in Relapsed/Refractory Mantle Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma: primary endpoint results, effect estimate with…
- An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD: Complete Statistical AnalysisIndependent statistical analysis of An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia: Complete Statistical AnalysisIndependent statistical analysis of An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Exploratory Study of Nasonex in Patients With Moderate to Severe Persistent Allergic Rhinitis and Intermittent Asthma: Complete Statistical AnalysisIndependent statistical analysis of An Exploratory Study of Nasonex in Patients With Moderate to Severe Persistent Allergic Rhinitis and Intermittent Asthma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- An Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study of LAQ/5062 Exploring the Long Term Safety, Tolerability and Clinical Effect Parameters During the Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia: Complete Statistical AnalysisIndependent statistical analysis of An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia: primary endpoint results, effect estimate with confidence interval, sample-size…
- An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of An Global Comparative Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: Complete Statistical AnalysisIndependent statistical analysis of An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.: Complete Statistical AnalysisIndependent statistical analysis of An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR: Complete Statistical AnalysisIndependent statistical analysis of An Long-term Follow-up Trial of Kidney Tx Patients Treated With Imlifidase or PE After an AMR: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- An Open Label Study for Participants With Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of An Open Label Study for Participants With Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01215942).
- An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis: Complete Statistical AnalysisIndependent statistical analysis of An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- anaGOIndependent statistical analysis of A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease: Complete Statistical AnalysisIndependent statistical analysis of Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00069329).