Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- CV_WIZARDIndependent statistical analysis of CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- D2P3Independent statistical analysis of Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites: Complete Statistical AnalysisIndependent statistical analysis of Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites: primary endpoint results, effect estimate with confidence interval,…
- DAPHNEIndependent statistical analysis of Long-term Study of Duodopa (Levodopa/Carbidopa) in Advanced Parkinson's: Health Outcomes & Net Economic Impact: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- DAPPERIndependent statistical analysis of Depression and Pain Perseverance Through Empowered Recovery Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04091347).
- Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme: Complete Statistical AnalysisIndependent statistical analysis of Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma: Complete Statistical AnalysisIndependent statistical analysis of Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00423735).
- DAYBREAK-ALZIndependent statistical analysis of A Study of Lanabecestat (LY3314814) in Participants With Mild Alzheimer's Disease Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- DEIndependent statistical analysis of Effects of Robotic Versus Manually-Assisted Locomotor Training for Individuals With Incomplete Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- DEBRAIndependent statistical analysis of Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Decision Making Tool for Firearm Storage: Complete Statistical AnalysisIndependent statistical analysis of Decision Making Tool for Firearm Storage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06382194).
- DEFINEIndependent statistical analysis of DEFINE (NCT00420212), a phase 3 randomized, double-blind trial of oral BG00012 in relapsing-remitting multiple sclerosis, focusing on its 2-year time-to-event endpoint and statistical methodology.
- DEFUSE 3Independent statistical analysis of Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02586415).
- Dementia Symptom Management at Home Program: Complete Statistical AnalysisIndependent statistical analysis of Dementia Symptom Management at Home Program: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03255967).
- Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers: Complete Statistical AnalysisIndependent statistical analysis of Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Developing an Activity Pacing Framework: Feasibility and Acceptability: Complete Statistical AnalysisIndependent statistical analysis of Developing an Activity Pacing Framework: Feasibility and Acceptability: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03497585).
- Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department: Complete Statistical AnalysisIndependent statistical analysis of Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Developing an Online Therapeutic Intervention for Chronic Pain in Veterans: Complete Statistical AnalysisIndependent statistical analysis of Developing an Online Therapeutic Intervention for Chronic Pain in Veterans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03655132).
- Developing and Testing a Comprehensive MS Spasticity Management Program: Complete Statistical AnalysisIndependent statistical analysis of Developing and Testing a Comprehensive MS Spasticity Management Program: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02170779).
- Development of Low Cost Devices to Increase Access to Treadmill Training: Complete Statistical AnalysisIndependent statistical analysis of Development of Low Cost Devices to Increase Access to Treadmill Training: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids: Complete Statistical AnalysisIndependent statistical analysis of Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- DEX-TRA 02Independent statistical analysis of Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain: primary endpoint results, effect estimate with confidence interval, sample-size…
- Dexamethasone for Migraine – Dose Comparison: Complete Statistical AnalysisIndependent statistical analysis of Dexamethasone for Migraine - Dose Comparison: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04112823).
- DexMabIndependent statistical analysis of Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal: Complete Statistical AnalysisIndependent statistical analysis of Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04470050).
- Dexmedetomidine-ketamine in Femur Proximal Fracture Patients: Complete Statistical AnalysisIndependent statistical analysis of Dexmedetomidine-ketamine in Femur Proximal Fracture Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02150759).
- DIAS-2Independent statistical analysis of the randomized phase 3 DIAS-2 trial of desmoteplase in acute ischemic stroke, including its design, functional endpoints, planned statistical analysis, and interpretation.
- Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness: Complete Statistical AnalysisIndependent statistical analysis of Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Dietary Salt in Postural Tachycardia Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Dietary Salt in Postural Tachycardia Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01547117).
- Digital Knee Osteoarthritis Mindset Intervention: Complete Statistical AnalysisIndependent statistical analysis of Digital Knee Osteoarthritis Mindset Intervention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05698368).
- Dimethyl Fumarate for Obstructive Sleep Apnea: Complete Statistical AnalysisIndependent statistical analysis of Dimethyl Fumarate for Obstructive Sleep Apnea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02438137).
- DIODEIndependent statistical analysis of De-Implementing Opioids for Dental Extractions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03584789).
- DIRECT-MTIndependent statistical analysis of DIRECT-MT (NCT03469206), a randomized trial of intra-arterial thrombectomy versus intravenous thrombolysis in patients with acute ischemic stroke and large vessel occlusion.
- Discrete Versus Rhythmic Gait Training: Complete Statistical AnalysisIndependent statistical analysis of Discrete Versus Rhythmic Gait Training: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02650440).
- DLSEAIndependent statistical analysis of Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory): primary endpoint…
- Does Improving Vagal Tone Increase Mitochondrial Bioenergetics: Complete Statistical AnalysisIndependent statistical analysis of Does Improving Vagal Tone Increase Mitochondrial Bioenergetics: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03931330).
- Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?: Complete Statistical AnalysisIndependent statistical analysis of Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients: Complete Statistical AnalysisIndependent statistical analysis of Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?: Complete Statistical AnalysisIndependent statistical analysis of Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01231646).
- Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults: Complete Statistical AnalysisIndependent statistical analysis of Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults: primary endpoint results, effect estimate with confidence…
- DOPAACRO 002Independent statistical analysis of Assessment of BIM23B065, Given as Repeated Subcutaneous Injection in Subjects With Acromegaly: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures: Complete Statistical AnalysisIndependent statistical analysis of Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy: Complete Statistical AnalysisIndependent statistical analysis of Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy: primary endpoint results, effect estimate with confidence…
- Driving Neuroplasticity With Nerve Stimulation and Modified CIT: Complete Statistical AnalysisIndependent statistical analysis of Driving Neuroplasticity With Nerve Stimulation and Modified CIT: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02587234).
- Drug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of Drug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- DSC2UIndependent statistical analysis of An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Duloxetine in Patients With Diabetic in Peripheral Neuropathic Pain With or Without Co-morbid Major Depressive Disorder: Complete Statistical AnalysisIndependent statistical analysis of Duloxetine in Patients With Diabetic in Peripheral Neuropathic Pain With or Without Co-morbid Major Depressive Disorder: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine: Complete Statistical AnalysisIndependent statistical analysis of Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02037425).
- DysmenorrheaIndependent statistical analysis of Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00517556).
- Dysport® Adult Upper Limb Spasticity Extension Study: Complete Statistical AnalysisIndependent statistical analysis of Dysport® Adult Upper Limb Spasticity Extension Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01313312).