Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Dysport® Pediatric Lower Limb Spasticity Follow-on Study: Complete Statistical AnalysisIndependent statistical analysis of Dysport® Pediatric Lower Limb Spasticity Follow-on Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01251380).
- DYSTANCE 51Independent statistical analysis of Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS): Complete Statistical AnalysisIndependent statistical analysis of E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- EAST-AFNET 4Independent statistical analysis and educational interpretation of EAST-AFNET 4, a randomized phase 4 trial evaluating early standardized rhythm control in atrial fibrillation.
- ED-DDPIndependent statistical analysis of Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- EDITH-HCIndependent statistical analysis of Pilot Testing Dementia-Enhanced Training and Tool for Home Hospice Clinicians: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05719077).
- EduCanIndependent statistical analysis of Effectiveness of a Modern Educational Intervention in Breast Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03351075).
- Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide: Complete Statistical AnalysisIndependent statistical analysis of Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Effect of BIA 9-1067 on the Pharmacokinetics and Pharmacodynamics of Warfarin: Complete Statistical AnalysisIndependent statistical analysis of Effect of BIA 9-1067 on the Pharmacokinetics and Pharmacodynamics of Warfarin: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effect of BIA 9-1067 on the Pharmacokinetics of Repaglinide: Complete Statistical AnalysisIndependent statistical analysis of Effect of BIA 9-1067 on the Pharmacokinetics of Repaglinide: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01536366).
- Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke: Complete Statistical AnalysisIndependent statistical analysis of Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03099005).
- Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03271151).
- Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory: Complete Statistical AnalysisIndependent statistical analysis of Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effect of EPA and DHA in the Inflammation and Metabolic Disorders in DMD/DMB Patients: Complete Statistical AnalysisIndependent statistical analysis of Effect of EPA and DHA in the Inflammation and Metabolic Disorders in DMD/DMB Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina: Complete Statistical AnalysisIndependent statistical analysis of Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft: Complete Statistical AnalysisIndependent statistical analysis of Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Effect of Lidocaine and Esmolol to Improve the Quality of Recovery: Complete Statistical AnalysisIndependent statistical analysis of Effect of Lidocaine and Esmolol to Improve the Quality of Recovery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ – Sleep Apnoea: Complete Statistical AnalysisIndependent statistical analysis of Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Effect of Lumbar Bracing on Spinal Function: Complete Statistical AnalysisIndependent statistical analysis of Effect of Lumbar Bracing on Spinal Function: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02251106).
- Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effect Of Ophiochepalus Striatus Extract On Serum IGF-1 And IL-6 Levels In Elderly Patients With Sarcopenia: Complete Statistical AnalysisIndependent statistical analysis of Effect Of Ophiochepalus Striatus Extract On Serum IGF-1 And IL-6 Levels In Elderly Patients With Sarcopenia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Effect of Perioperative Gabapentin on Postoperative Opioid Requirements: Complete Statistical AnalysisIndependent statistical analysis of Effect of Perioperative Gabapentin on Postoperative Opioid Requirements: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05494385).
- Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy: Complete Statistical AnalysisIndependent statistical analysis of Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Effect of Spinal Ketorolac After Acute Opioid Exposure: Complete Statistical AnalysisIndependent statistical analysis of Effect of Spinal Ketorolac After Acute Opioid Exposure: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00693160).
- Effect of Telehealth Mindfulness on Sleep and Anxiety in Acquired Brain Injury Population: Complete Statistical AnalysisIndependent statistical analysis of Effect of Telehealth Mindfulness on Sleep and Anxiety in Acquired Brain Injury Population: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children: Complete Statistical AnalysisIndependent statistical analysis of Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Effect of Valproic Acid Concentration on Photic Response: Complete Statistical AnalysisIndependent statistical analysis of Effect of Valproic Acid Concentration on Photic Response: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00609245).
- Effect of Vibration Exercise on Upper Limb Strength, Function, and Pain: Complete Statistical AnalysisIndependent statistical analysis of Effect of Vibration Exercise on Upper Limb Strength, Function, and Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA: Complete Statistical AnalysisIndependent statistical analysis of Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline: primary endpoint results, effect estimate with confidence interval, sample-size…
- Effectiveness of Lumbar Facet Joint Nerve Blocks: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Lumbar Facet Joint Nerve Blocks: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00355914).
- Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02743702).
- Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation: Complete Statistical AnalysisIndependent statistical analysis of Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients: Complete Statistical AnalysisIndependent statistical analysis of Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia: Complete Statistical AnalysisIndependent statistical analysis of Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Effects of Biofeedback in Patients With Acute Cerebral Infarction: Complete Statistical AnalysisIndependent statistical analysis of Effects of Biofeedback in Patients With Acute Cerebral Infarction: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03516227).
- Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack: Complete Statistical AnalysisIndependent statistical analysis of Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00929994).
- Effects of Cholinergic Augmentation on Measures of Balance and Gait: Complete Statistical AnalysisIndependent statistical analysis of Effects of Cholinergic Augmentation on Measures of Balance and Gait: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02206620).
- Effects of Cladribine Tablets on the PK of Microgynon®: Complete Statistical AnalysisIndependent statistical analysis of Effects of Cladribine Tablets on the PK of Microgynon®: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03745144).
- Effects of Exenatide on Overweight Adolescents With Prader-Willi Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Effects of Exenatide on Overweight Adolescents With Prader-Willi Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01444898).
- Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain: Complete Statistical AnalysisIndependent statistical analysis of Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency: Complete Statistical AnalysisIndependent statistical analysis of Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy: Complete Statistical AnalysisIndependent statistical analysis of Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve: Complete Statistical AnalysisIndependent statistical analysis of Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors: Complete Statistical AnalysisIndependent statistical analysis of Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01100658).
- Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Effects of Programming Parameters on Back Pain Relief in Subthreshold Spinal Cord Stimulation: Complete Statistical AnalysisIndependent statistical analysis of Effects of Programming Parameters on Back Pain Relief in Subthreshold Spinal Cord Stimulation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…