Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- ENCOREIndependent statistical analysis of Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- ENFORCEIndependent statistical analysis of A Study to Explore the Long-Term Safety and Efficacy of Fremanezumab (TEV-48125) for the Prevention of Cluster Headache: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- ENGAGE AF-TIMI 48Independent statistical analysis of ENGAGE AF-TIMI 48, evaluating edoxaban versus warfarin for stroke and systemic embolic events in patients with atrial fibrillation.
- ENGAGESIndependent statistical analysis of Electroencephalography Guidance of Anesthesia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02241655).
- Enhancing Plasticity in Stroke Patients With Severe Motor Deficit: Complete Statistical AnalysisIndependent statistical analysis of Enhancing Plasticity in Stroke Patients With Severe Motor Deficit: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02633215).
- ENVISIONIndependent statistical analysis of A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Epidural Neostigmine for Labor Pain: Complete Statistical AnalysisIndependent statistical analysis of Epidural Neostigmine for Labor Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00779467).
- EPITHETIndependent statistical analysis of the EPITHET phase 2 trial evaluating alteplase t-PA in acute stroke, including design, endpoints, planned methodology, and statistical interpretation.
- EPOCHIndependent statistical analysis of An Efficacy and Safety Trial of Verubecestat (MK-8931) in Mild to Moderate Alzheimer's Disease (P07738): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- EQUIPED-ADRDIndependent statistical analysis of Enhanced Quality in Primary Care for Elders With Diabetes and Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma: Complete Statistical AnalysisIndependent statistical analysis of Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- ESCAPEIndependent statistical analysis of Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- ESETTIndependent statistical analysis of Established Status Epilepticus Treatment Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01960075).
- Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans: Complete Statistical AnalysisIndependent statistical analysis of Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- ETA-TVIndependent statistical analysis of EYE-TRAC Advance: Technology Verification (ETA-TV) Cohort 2: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02877732).
- Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer: Complete Statistical AnalysisIndependent statistical analysis of Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- EVA-3SAn independent statistical analysis of EVA-3S, a phase 3 randomized trial concerning carotid angioplasty and stenting with cerebral protection in patients with severe symptomatic carotid stenosis.
- Evaluate Safety of Tramadol in the Management of Postoperative Pain Following Surgery: Complete Statistical AnalysisIndependent statistical analysis of Evaluate Safety of Tramadol in the Management of Postoperative Pain Following Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis: Complete Statistical AnalysisIndependent statistical analysis of Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Evaluation of Blood Volume and Perceived Pain During Fingerstick Monitoring of Blood Glucose: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Blood Volume and Perceived Pain During Fingerstick Monitoring of Blood Glucose: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction: primary endpoint results, effect estimate with confidence interval, sample-size…
- Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric Patients: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Evaluation of Efficacy and Safety of Suzetrigine for Acute Pain After an Abdominoplasty: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Efficacy and Safety of Suzetrigine for Acute Pain After an Abdominoplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Evaluation of Long-term Effect of Resonator Therapy on Parkinson’s Disease (PD): Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Long-term Effect of Resonator Therapy on Parkinson's Disease (PD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Evaluation of Persistence of Anti-meningococcal Bactericidal Antibodies Among Adolescents Who Previously Received MenACWY Conjugate Vaccine: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Persistence of Anti-meningococcal Bactericidal Antibodies Among Adolescents Who Previously Received MenACWY Conjugate Vaccine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Evaluation of Preoperative N1539 in Total Knee Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Preoperative N1539 in Total Knee Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03434275).
- Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Evaluation of Robotic Arm Rehabilitation in Stroke Patients: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Robotic Arm Rehabilitation in Stroke Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00333983).
- Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00678899).
- Evaluation of the Percutaneous SCS Trial Using the DSSEP Collision Testing: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Percutaneous SCS Trial Using the DSSEP Collision Testing: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.: Complete Statistical AnalysisIndependent statistical analysis of Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex: Complete Statistical AnalysisIndependent statistical analysis of Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Everolimus for Cancer With TSC1 or TSC2 Mutation: Complete Statistical AnalysisIndependent statistical analysis of Everolimus for Cancer With TSC1 or TSC2 Mutation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02201212).
- Evidence-based Intervention for Improved Head Impact Safety in Youth Football – Aim 1 and Aim 3: Complete Statistical AnalysisIndependent statistical analysis of Evidence-based Intervention for Improved Head Impact Safety in Youth Football - Aim 1 and Aim 3: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- EVOLVE-1Independent statistical analysis of the phase 3 EVOLVE-1 trial of galcanezumab for the prevention of episodic migraine, including randomized design, longitudinal mixed-effects analysis, odds ratios, Fisher exact testing, efficacy results, safety, and…
- EW-DIndependent statistical analysis of A Community Wellness Program for Adults Living With Long-term Physical Disability: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Exercise for Swallowing Problems After Stroke: Complete Statistical AnalysisIndependent statistical analysis of Exercise for Swallowing Problems After Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00722111).
- Exercise-induced Hypoalgesia After Comparative Forms of Exercise: Complete Statistical AnalysisIndependent statistical analysis of Exercise-induced Hypoalgesia After Comparative Forms of Exercise: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01883895).