Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Exparel for Total Shoulder Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Exparel for Total Shoulder Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04364867).
- Exparel vs. Standard Bupivicaine for Abdominoplasty: Complete Statistical AnalysisIndependent statistical analysis of Exparel vs. Standard Bupivicaine for Abdominoplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01853176).
- ExpeditionPROIndependent statistical analysis of A Study of Solanezumab (LY2062430) in Participants With Prodromal Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Expiratory Muscle Training in Stroke: Complete Statistical AnalysisIndependent statistical analysis of Expiratory Muscle Training in Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04569968).
- Exploration of Pupil Dilation in Horner’s Patients Taking Flomax: Complete Statistical AnalysisIndependent statistical analysis of Exploration of Pupil Dilation in Horner's Patients Taking Flomax: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03615508).
- Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities: Complete Statistical AnalysisIndependent statistical analysis of Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Exploratory Subjective Sleep Study of a Prototype Nasal Dilator: Complete Statistical AnalysisIndependent statistical analysis of Exploratory Subjective Sleep Study of a Prototype Nasal Dilator: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01122849).
- EXPLOREIndependent statistical analysis of EXPLORE (NCT04211454), a non-interventional pilot study exploring the role of gut flora in migraine headaches, including trial design, endpoints, planned analysis, and statistical interpretation.
- Exploring the Safety And Tolerability of Doses of E2007 up to a Maximum of 12 mg In Patients With Refractory Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of Exploring the Safety And Tolerability of Doses of E2007 up to a Maximum of 12 mg In Patients With Refractory Partial Seizures: primary endpoint results, effect estimate with…
- EXTENDAn independent statistical analysis of the EXTEND phase 3 trial of alteplase versus placebo in stroke, covering its randomized design, 3-month modified Rankin Scale endpoint, planned statistical analysis, and interpretation.
- EXTEND-IAIndependent statistical analysis of EXTEND-IA, a randomized phase 2 trial comparing tenecteplase with tissue plasminogen activator before endovascular therapy for ischemic stroke.
- Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children: Complete Statistical AnalysisIndependent statistical analysis of Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Extending taVNS Paired With Infant CIMT Into a Home-Based Setting: Complete Statistical AnalysisIndependent statistical analysis of Extending taVNS Paired With Infant CIMT Into a Home-Based Setting: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05857527).
- Extension Study Of Long-Term Safety And Efficacy Of Pregabalin As Monotherapy (Lyrica) In Patients With Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of Extension Study Of Long-Term Safety And Efficacy Of Pregabalin As Monotherapy (Lyrica) In Patients With Partial Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- External Trigeminal Nerve Stimulation for Epilepsy: Complete Statistical AnalysisIndependent statistical analysis of External Trigeminal Nerve Stimulation for Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01159431).
- Faith-Based Toolbox for African Americans With Dementia: Complete Statistical AnalysisIndependent statistical analysis of Faith-Based Toolbox for African Americans With Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04325204).
- Fall-recovery Training for Those With Chronic Stroke and Low Falls Self-efficacy: Complete Statistical AnalysisIndependent statistical analysis of Fall-recovery Training for Those With Chronic Stroke and Low Falls Self-efficacy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- FAME II – Fractional Flow Reserve (FFR) Guided Percutaneous Coronary Intervention (PCI) Plus Optimal Medical Treatment (OMT) Verses OMT: Complete Statistical AnalysisIndependent statistical analysis of FAME II - Fractional Flow Reserve (FFR) Guided Percutaneous Coronary Intervention (PCI) Plus Optimal Medical Treatment (OMT) Verses OMT: primary endpoint results, effect estimate with confidence interval, sample-size…
- FASTIndependent statistical analysis of Fast-Acting Subperception Study (FAST): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04231409).
- FASTIndependent statistical analysis of FAST as a Treatment for Obstructive Sleep Apnea: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01611779).
- FASTIndependent statistical analysis of Fundamental Asynchronous Stimulus Timing Sound Coding Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02698787).
- Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers: Complete Statistical AnalysisIndependent statistical analysis of Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers: primary endpoint results, effect estimate with…
- Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic Pain: Complete Statistical AnalysisIndependent statistical analysis of Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05017701).
- Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors: Complete Statistical AnalysisIndependent statistical analysis of Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Feasibility of Measuring Vertical Perception in Acute Stroke: Complete Statistical AnalysisIndependent statistical analysis of Feasibility of Measuring Vertical Perception in Acute Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06301815).
- Feasibility of Unattended Home Polysomnography and Comparison to In-laboratory Polysomnography in Pediatric Patients: Complete Statistical AnalysisIndependent statistical analysis of Feasibility of Unattended Home Polysomnography and Comparison to In-laboratory Polysomnography in Pediatric Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Feasibility Study of GlaxoSmithKline Biologicals’ GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.: Complete Statistical AnalysisIndependent statistical analysis of Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- FEAStIndependent statistical analysis of Fostering Eating After Stroke With Transcranial Direct Current Stimulation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01919112).
- Fenofibrate Treatment in SCI: Complete Statistical AnalysisIndependent statistical analysis of Fenofibrate Treatment in SCI: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02455336).
- Fentanyl for Breakthrough Pain in the Emergency Department: Complete Statistical AnalysisIndependent statistical analysis of Fentanyl for Breakthrough Pain in the Emergency Department: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01812759).
- Fetoscopic NEOX Cord 1K® Spina Bifida Repair: Complete Statistical AnalysisIndependent statistical analysis of Fetoscopic NEOX Cord 1K® Spina Bifida Repair: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04243889).
- First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study: Complete Statistical AnalysisIndependent statistical analysis of First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study: primary endpoint…
- First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221: Complete Statistical AnalysisIndependent statistical analysis of First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- FISATABIIndependent statistical analysis of Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04221009).
- Florbetapir Calibration to the Centiloid Scale: Complete Statistical AnalysisIndependent statistical analysis of Florbetapir Calibration to the Centiloid Scale: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02120664).
- Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma: Complete Statistical AnalysisIndependent statistical analysis of Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma: primary endpoint results, effect estimate with confidence interval, sample-size…
- Flumazenil for the Treatment of Primary Hypersomnia: Complete Statistical AnalysisIndependent statistical analysis of Flumazenil for the Treatment of Primary Hypersomnia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01183312).
- FLUORESCEIndependent statistical analysis of Fluoxetine for Visual Recovery After Ischemic Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02737930).
- Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters: Complete Statistical AnalysisIndependent statistical analysis of Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02678039).
- FOCUSComplete statistical analysis of the FOCUS randomized phase 3 trial comparing liberal and restrictive blood transfusion strategies in surgical patients with cardiovascular disease, including endpoint definitions, reported odds ratios and risk differences,…
- FOCUSIndependent statistical analysis of An Efficacy and Safety Study of Fremanezumab in Adults With Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- FOGIndependent statistical analysis of Amyloidopathy, Cholinopathy, Dopamine Responsiveness and Freezing of Gait in PD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03647137).
- FREEDOMSIndependent statistical analysis of the FREEDOMS phase 3 trial of fingolimod in relapsing-remitting multiple sclerosis, covering randomized design, annualized relapse rate, statistical methodology, safety, and interpretation.
- FREEDOMS IIIndependent statistical analysis of Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing-remitting Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- FSHDIndependent statistical analysis of Efficacy and Safety of Losmapimod in Subjects With Facioscapulohumeral Muscular Dystrophy (FSHD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke: Complete Statistical AnalysisIndependent statistical analysis of Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00142792).
- Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke: Complete Statistical AnalysisIndependent statistical analysis of Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02199795).
- Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response: Complete Statistical AnalysisIndependent statistical analysis of Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02495883).