Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- FX-322 in Sensorineural Hearing Loss: Complete Statistical AnalysisIndependent statistical analysis of FX-322 in Sensorineural Hearing Loss: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03616223).
- FX-LEARNIndependent statistical analysis of AFQ056 for Language Learning in Children With FXS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02920892).
- Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD): Complete Statistical AnalysisIndependent statistical analysis of Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01138124).
- GALAComplete statistical analysis of the phase 3 GALA trial of glatiramer acetate 40 mg three times weekly versus placebo in relapsing-remitting multiple sclerosis, including trial design, relapse endpoints, MRI outcomes, statistical methodology,…
- GAMES-PILOTIndependent statistical analysis of Glyburide Advantage in Malignant Edema and Stroke Pilot: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01268683).
- Gas ChallengeIndependent statistical analysis of Human Cerebral Blood Flow Regulation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04265053).
- GATEWAYIndependent statistical analysis of A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- GAVOTTEIndependent statistical analysis of A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS): primary endpoint results, effect…
- GDX-44-016Independent statistical analysis of Performance of Elucirem in DSC-MRI Perfusion of Brain Gliomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06057168).
- Genetic Effects on Dopamine Response to an Opiate: Complete Statistical AnalysisIndependent statistical analysis of Genetic Effects on Dopamine Response to an Opiate: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01878006).
- Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas: Complete Statistical AnalysisIndependent statistical analysis of Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury: Complete Statistical AnalysisIndependent statistical analysis of Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Geriatric Ketamine for Pain Management Study: Complete Statistical AnalysisIndependent statistical analysis of Geriatric Ketamine for Pain Management Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02673372).
- GLEAMIndependent statistical analysis of A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME): primary endpoint results, effect estimate with confidence…
- Global Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Women With Moderate to Severe Endometriosis-associated Pain: Complete Statistical AnalysisIndependent statistical analysis of Global Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Women With Moderate to Severe Endometriosis-associated Pain: primary endpoint results, effect estimate with confidence interval, sample-size…
- Glucose Regulation in Acute Stroke Patients (GRASP) Study: Complete Statistical AnalysisIndependent statistical analysis of Glucose Regulation in Acute Stroke Patients (GRASP) Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00282867).
- GLUMIT-DGIndependent statistical analysis of Continuous Glucose Monitoring and Insulin Pump Therapy in Diabetic Gastroparesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01030341).
- GRABM-LIndependent statistical analysis of GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- GRAY-BIndependent statistical analysis of GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Greater Occipital Nerve Block Versus Metoclopramide: Complete Statistical AnalysisIndependent statistical analysis of Greater Occipital Nerve Block Versus Metoclopramide: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03269435).
- Growth-TBIIndependent statistical analysis of Recombinant Human Growth Hormone During Rehabilitation From Traumatic Brain Injury.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00766038).
- gustinpropIndependent statistical analysis of Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01097915).
- GWIIRTIndependent statistical analysis of Gulf War Illness Inflammation Reduction Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02506192).
- GWPCARE5Independent statistical analysis of An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Adults With Dravet or Lennox-Gastaut Syndromes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers: Complete Statistical AnalysisIndependent statistical analysis of Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms: Complete Statistical AnalysisIndependent statistical analysis of HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- HDVRIndependent statistical analysis of Hoarding Disorder Treatment With Virtual Reality: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03828461).
- headpodIndependent statistical analysis of Measuring Head Control Change With 2D Video Analysis After Utilization of Headpod in Children With Poor Head Control: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- HEAL-LAAIndependent statistical analysis of HEAL-LAA Clinical Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05809596).
- Hearing Aid Signal Processing Comparative Study: Complete Statistical AnalysisIndependent statistical analysis of Hearing Aid Signal Processing Comparative Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04839289).
- Hemodynamic Effects of Compression in POTS: Complete Statistical AnalysisIndependent statistical analysis of Hemodynamic Effects of Compression in POTS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03484273).
- Heritability of Opioid Effects: A Twin Study: Complete Statistical AnalysisIndependent statistical analysis of Heritability of Opioid Effects: A Twin Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00672438).
- HFSCSIndependent statistical analysis of High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- HIDO-LIDOIndependent statistical analysis of High Dose IV Lidocaine vs Hydromorphone for Abdominal Pain in the Emergency Department: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions: Complete Statistical AnalysisIndependent statistical analysis of High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- High Dose or High Dose Frequency Study of Alglucosidase Alfa: Complete Statistical AnalysisIndependent statistical analysis of High Dose or High Dose Frequency Study of Alglucosidase Alfa: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00483379).
- High Dose Oxytocin Nasal Spray for Treatment of Tinnitus: Complete Statistical AnalysisIndependent statistical analysis of High Dose Oxytocin Nasal Spray for Treatment of Tinnitus: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04210310).
- High Frequency Impulse Therapy for Neuropathic Pain in NMOSD: Complete Statistical AnalysisIndependent statistical analysis of High Frequency Impulse Therapy for Neuropathic Pain in NMOSD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04614454).
- HIIT-SCIIndependent statistical analysis of Feasibility of HIIT in Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03152110).
- Historical Case Record Survey of Visual Acuity Data From Patients With Leber’s Hereditary Optic Neuropathy (LHON): Complete Statistical AnalysisIndependent statistical analysis of Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Home-based Telehealth Stroke Care: A Randomized Trial for Veterans: Complete Statistical AnalysisIndependent statistical analysis of Home-based Telehealth Stroke Care: A Randomized Trial for Veterans: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00384748).
- Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer’s Disease and Related Dementias (ADRD): Complete Statistical AnalysisIndependent statistical analysis of Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- HOPE-2-OLEIndependent statistical analysis of Open-label Extension of the HOPE-2 Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04428476).
- HOPE-3Independent statistical analysis of HOPE-3, a randomized phase 4 factorial trial evaluating candesartan/HCT and rosuvastatin for prevention in cardiovascular disease and stroke, including its composite endpoints, factorial design, and planned statistical analysis.
- HSCT for High Risk Inherited Inborn Errors: Complete Statistical AnalysisIndependent statistical analysis of HSCT for High Risk Inherited Inborn Errors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00383448).
- HYPEROXIA Responses and ROS: Complete Statistical AnalysisIndependent statistical analysis of HYPEROXIA Responses and ROS: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05958303).
- HYVETIndependent statistical analysis of HYVET, the Hypertension in the Very Elderly Trial, including trial design, endpoints, planned methodology, statistical interpretation, limitations, and educational concepts.
- I2PETHVIndependent statistical analysis of I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02323217).
- Ibuprofen Extended-Release Dental Pain Study: Complete Statistical AnalysisIndependent statistical analysis of Ibuprofen Extended-Release Dental Pain Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00707057).
- Ibuprofen With or Without Acetaminophen for Low Back Pain: Complete Statistical AnalysisIndependent statistical analysis of Ibuprofen With or Without Acetaminophen for Low Back Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03554018).