Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- iCareIndependent statistical analysis of iCare Stress Management e-Training for Dementia Family Caregivers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01378195).
- ICEIndependent statistical analysis of Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00220740).
- Ictal and Interictal Inflammatory Markers in Migraine: Complete Statistical AnalysisIndependent statistical analysis of Ictal and Interictal Inflammatory Markers in Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01138150).
- IDENTITY-2Independent statistical analysis of Effects of LY450139, on the Progression of Alzheimer's Disease as Compared With Placebo: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis: Complete Statistical AnalysisIndependent statistical analysis of Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach: Complete Statistical AnalysisIndependent statistical analysis of Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Immediate-Release Oxycodone Capsules Study in Cancer Pain: Complete Statistical AnalysisIndependent statistical analysis of Immediate-Release Oxycodone Capsules Study in Cancer Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01675622).
- Immersive Virtual Reality Bicycling for Persons With Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Immersive Virtual Reality Bicycling for Persons With Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05160025).
- Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 18 Years in Taiwan: Complete Statistical AnalysisIndependent statistical analysis of Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 18 Years in Taiwan: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- IMPACTIndependent statistical analysis of Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production: Complete Statistical AnalysisIndependent statistical analysis of Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03883724).
- Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies: Complete Statistical AnalysisIndependent statistical analysis of Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Impact of Helmet Use in Preschool Children: Complete Statistical AnalysisIndependent statistical analysis of Impact of Helmet Use in Preschool Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01054846).
- Impact of Hot Flashes on Sleep and Mood Disturbance: Complete Statistical AnalysisIndependent statistical analysis of Impact of Hot Flashes on Sleep and Mood Disturbance: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01116401).
- Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep: Complete Statistical AnalysisIndependent statistical analysis of Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Impact of Pushrim Activated Power Assist Wheelchairs on Mobility Among People With Tetraplegia: Complete Statistical AnalysisIndependent statistical analysis of Impact of Pushrim Activated Power Assist Wheelchairs on Mobility Among People With Tetraplegia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Impact of Vitamin A Supplementation on Immune System in Multiple Sclerosis Patients: Complete Statistical AnalysisIndependent statistical analysis of Impact of Vitamin A Supplementation on Immune System in Multiple Sclerosis Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care: Complete Statistical AnalysisIndependent statistical analysis of Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- IMPROVEIndependent statistical analysis of An Evaluation of MBSR and CBT for Veterans With Chronic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Improving Cancer Pain Management Through Self-Care: Complete Statistical AnalysisIndependent statistical analysis of Improving Cancer Pain Management Through Self-Care: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00708019).
- Improving Motor Function After Spinal Cord Injury: Complete Statistical AnalysisIndependent statistical analysis of Improving Motor Function After Spinal Cord Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01915095).
- Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring: Complete Statistical AnalysisIndependent statistical analysis of Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00682838).
- Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients: Complete Statistical AnalysisIndependent statistical analysis of Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01284140).
- In-home Cycling for Individuals With PD: Feasibility: Complete Statistical AnalysisIndependent statistical analysis of In-home Cycling for Individuals With PD: Feasibility: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04300023).
- In-Home Technology for Dementia Caregivers: Complete Statistical AnalysisIndependent statistical analysis of In-Home Technology for Dementia Caregivers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03828383).
- Individualized Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations: Complete Statistical AnalysisIndependent statistical analysis of Individualized Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05319080).
- INOVAOPIOIDIndependent statistical analysis of Effectiveness of an Opioid Sparing Pain Regimen in Cardiac Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03679013).
- INSIGHTIndependent statistical analysis of Extension Study to Study PQ-110-001 (NCT03140969): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03913130).
- INSPIRESA detailed statistical analysis of the INSPIRES phase 3 factorial trial of intensive medical therapy for high-risk intracranial or extracranial atherosclerosis, including its design, 90-day stroke endpoint, planned analysis framework, and statistical…
- INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage: Complete Statistical AnalysisIndependent statistical analysis of INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Investigating Hearing With Ponto 3 SuperPower, a Bone Anchored Hearing Aid – Investigating Hear: Complete Statistical AnalysisIndependent statistical analysis of Investigating Hearing With Ponto 3 SuperPower, a Bone Anchored Hearing Aid - Investigating Hear: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis: Complete Statistical AnalysisIndependent statistical analysis of Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04343716).
- Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches: Complete Statistical AnalysisIndependent statistical analysis of Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Investigation of Trunk Muscle Size and Function in Older Adults With Chronic Low Back Pain: Complete Statistical AnalysisIndependent statistical analysis of Investigation of Trunk Muscle Size and Function in Older Adults With Chronic Low Back Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Investigational Study of the Ekso for High-Dosage Use by Individuals With SCI in a Non-Clinical Environment: Complete Statistical AnalysisIndependent statistical analysis of Investigational Study of the Ekso for High-Dosage Use by Individuals With SCI in a Non-Clinical Environment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- IRISComplete statistical analysis of the IRIS trial of pioglitazone versus placebo after stroke or myocardial infarction, including trial design, time-to-event endpoints, Cox modeling, mixed-effects analysis, multiplicity, interim analysis, results, and statistical interpretation.
- IRMAIndependent statistical analysis of Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- IU-CHOICEIndependent statistical analysis of Indiana University Dementia Screening Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01699503).
- IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair: Complete Statistical AnalysisIndependent statistical analysis of IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02155738).
- IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy: Complete Statistical AnalysisIndependent statistical analysis of IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02400580).
- IV APAP SFIndependent statistical analysis of Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3: Complete Statistical AnalysisIndependent statistical analysis of IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03401073).
- Japanese IP-TN Trial: Complete Statistical AnalysisIndependent statistical analysis of Japanese IP-TN Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02831569).
- JPN ATO OLEIndependent statistical analysis of A Study Evaluating Oral Atogepant for the Prevention of Migraine in Japanese Participants With Chronic or Episodic Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Juno Perth Clinical Trial: Complete Statistical AnalysisIndependent statistical analysis of Juno Perth Clinical Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02317042).
- KEM-VOCIndependent statistical analysis of Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02434939).
- KETAMINEIndependent statistical analysis of Administration of Ketamine to Prevent the Post-operative Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00210210).
- Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study: Complete Statistical AnalysisIndependent statistical analysis of Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Ketamine Patient-Controlled Analgesia for Acute Pain: Complete Statistical AnalysisIndependent statistical analysis of Ketamine Patient-Controlled Analgesia for Acute Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02062879).