Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1): Complete Statistical AnalysisIndependent statistical analysis of Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- KetoPltAggIndependent statistical analysis of IV Ketorolac on Platelet Function Post-Cesarean Delivery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03805607).
- KetPTSDIndependent statistical analysis of Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00749203).
- KINETICIndependent statistical analysis of Ketamine to Improve Recovery After Cesarean Delivery - Part 1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04037085).
- KOMETIndependent statistical analysis of Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- KPL-301 for Subjects With Giant Cell Arteritis: Complete Statistical AnalysisIndependent statistical analysis of KPL-301 for Subjects With Giant Cell Arteritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03827018).
- L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1: Complete Statistical AnalysisIndependent statistical analysis of L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01733407).
- Labetalol and Esmolol: Vital Signs and Post Operative Pain Management: Complete Statistical AnalysisIndependent statistical analysis of Labetalol and Esmolol: Vital Signs and Post Operative Pain Management: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01114971).
- Lamotrigine Bioequivalence: Complete Statistical AnalysisIndependent statistical analysis of Lamotrigine Bioequivalence: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01995825).
- Lamotrigine Extended-Release In Elderly Patients With Epilepsy: Complete Statistical AnalysisIndependent statistical analysis of Lamotrigine Extended-Release In Elderly Patients With Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00516139).
- LAMPIndependent statistical analysis of Learning to Apply Mindfulness to Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04526158).
- Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic Patients: Complete Statistical AnalysisIndependent statistical analysis of Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00383708).
- LANTERNIndependent statistical analysis of Efficacy and Safety of Lanreotide Autogel® 60, 90 or 120 mg With Lanreotide 40 mg Prolonged Release (PR) in Acromegaly: primary endpoint results, effect estimate with confidence interval,…
- Late-Onset Treatment Study Extension Protocol: Complete Statistical AnalysisIndependent statistical analysis of Late-Onset Treatment Study Extension Protocol: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00455195).
- LEAPSIndependent statistical analysis of Locomotor Experience Applied Post Stroke Trial: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00243919).
- Learning Impairments Among Survivors of Childhood Cancer: Complete Statistical AnalysisIndependent statistical analysis of Learning Impairments Among Survivors of Childhood Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00576472).
- LED Therapy for the Treatment of Concussive Brain Injury: Complete Statistical AnalysisIndependent statistical analysis of LED Therapy for the Treatment of Concussive Brain Injury: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02383472).
- LEMTRADA-ITPIndependent statistical analysis of Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures: Complete Statistical AnalysisIndependent statistical analysis of Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Levetiracetam Versus Valproate in Idiopathic Generalized Tonic-clonic Seizures: Complete Statistical AnalysisIndependent statistical analysis of Levetiracetam Versus Valproate in Idiopathic Generalized Tonic-clonic Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03940326).
- LIBERATE – LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs: Complete Statistical AnalysisIndependent statistical analysis of LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03887650).
- Lidocaine Injection and Ischemic Compression on Chronic Pelvic Pain Treatment: Complete Statistical AnalysisIndependent statistical analysis of Lidocaine Injection and Ischemic Compression on Chronic Pelvic Pain Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00628355).
- Lifeflight: Fentanyl Versus Morphine: Complete Statistical AnalysisIndependent statistical analysis of Lifeflight: Fentanyl Versus Morphine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00580489).
- Light Treatment to Improve Symptom Management of Fibromyalgia Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Light Treatment to Improve Symptom Management of Fibromyalgia Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03794908).
- Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- LittlEarsIndependent statistical analysis of Littlears Auditory Questionnaire: Validation Study in CI Children: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00785707).
- Local Injection of Local Anesthetic 24 Hours After Knee Replacement Surgery May Decrease Pain for Several More Hours: Complete Statistical AnalysisIndependent statistical analysis of Local Injection of Local Anesthetic 24 Hours After Knee Replacement Surgery May Decrease Pain for Several More Hours: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- LOGRIBMETIndependent statistical analysis of Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Long Term Follow-up Study With Keppra XR (Levetiracetam XR) for Partial Seizures: Complete Statistical AnalysisIndependent statistical analysis of Long Term Follow-up Study With Keppra XR (Levetiracetam XR) for Partial Seizures: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Long Term Immunity and Safety Following Vaccination With the JEV IC51 (IXIARO®, JESPECT®) in Pediatric Population In Non Endemic Countries. Uncontrolled, Ph3 FU-Study: Complete Statistical AnalysisIndependent statistical analysis of Long Term Immunity and Safety Following Vaccination With the JEV IC51 (IXIARO®, JESPECT®) in Pediatric Population In Non Endemic Countries. Uncontrolled, Ph3 FU-Study: primary endpoint results, effect estimate…
- Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia: Complete Statistical AnalysisIndependent statistical analysis of Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Long Term Safety of Teriflunomide When Added to Interferon-Beta or Glatiramer Acetate in Patients With Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of Long Term Safety of Teriflunomide When Added to Interferon-Beta or Glatiramer Acetate in Patients With Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer: Complete Statistical AnalysisIndependent statistical analysis of Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS): Complete Statistical AnalysisIndependent statistical analysis of Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS): primary endpoint results, effect estimate with confidence interval, sample-size planning…
- Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD): Complete Statistical AnalysisIndependent statistical analysis of Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Long-term Open-Label Safety Study to Evaluate EN3409: Complete Statistical AnalysisIndependent statistical analysis of Long-term Open-Label Safety Study to Evaluate EN3409: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01755546).
- Long-term Outcomes After Percutaneous Closure of PFO: Complete Statistical AnalysisIndependent statistical analysis of Long-term Outcomes After Percutaneous Closure of PFO: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05558774).
- Long-Term Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children Who Completed OTR3001: Complete Statistical AnalysisIndependent statistical analysis of Long-Term Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children Who Completed OTR3001: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Long-Term Study of Gabapentin Enacarbil (GEn, XP13512) vs. Placebo in Patients With Restless Legs Syndrome.: Complete Statistical AnalysisIndependent statistical analysis of Long-Term Study of Gabapentin Enacarbil (GEn, XP13512) vs. Placebo in Patients With Restless Legs Syndrome.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Long-Term Study of Nitisinone to Treat Alkaptonuria: Complete Statistical AnalysisIndependent statistical analysis of Long-Term Study of Nitisinone to Treat Alkaptonuria: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00107783).
- LOOPAn independent statistical analysis of the LOOP trial of implantable loop recorder monitoring, including trial design, the primary stroke or systemic arterial embolism endpoint, planned time-to-event analysis, and statistical interpretation.
- LOVIT IIIndependent statistical analysis of Low Vision Intervention Trial II (LOVIT II): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00958360).
- Low Intensity Ultrasound Therapy for Upper Back Pain Relief: Complete Statistical AnalysisIndependent statistical analysis of Low Intensity Ultrasound Therapy for Upper Back Pain Relief: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02135094).
- M-F0434Independent statistical analysis of Neuropathic Pain Management: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01263132).
- M032-HSV-1Independent statistical analysis of Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- MADIndependent statistical analysis of Mandibular Advancement Device and Changes in Nocturia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05562388).
- Magnesium vs Placebo for Tonsillectomy: Complete Statistical AnalysisIndependent statistical analysis of Magnesium vs Placebo for Tonsillectomy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02218424).
- MAGNET (Magnetically Controlled Capsule for Assessment of Gastric Mucosa in Symptomatic Patients): Complete Statistical AnalysisIndependent statistical analysis of MAGNET (Magnetically Controlled Capsule for Assessment of Gastric Mucosa in Symptomatic Patients): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Magnetic Resonance Spectroscopy Imaging in Predicting Response to Vorinostat and Temozolomide in Patients With Recurrent or Progressive Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning…