Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
816 results
- A Placebo Controlled Trial of Dalfampridine ER for Ambulatory Activity in People With Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Placebo Controlled Trial of Dalfampridine ER for Ambulatory Activity in People With Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine: Complete Statistical AnalysisIndependent statistical analysis of A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093: Complete Statistical AnalysisIndependent statistical analysis of A Placebo-controlled Study to Investigate Safety and Efficacy of BIA 2-093: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients (Study E2080-J081-304): Complete Statistical AnalysisIndependent statistical analysis of A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients (Study E2080-J081-304): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Positive Psychology Intervention for Patients With Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Positive Psychology Intervention for Patients With Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03637699).
- A Proof of Concept Study of the Efficacy and Safety of Oral LAT8881 in Acute Migraine: Complete Statistical AnalysisIndependent statistical analysis of A Proof of Concept Study of the Efficacy and Safety of Oral LAT8881 in Acute Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Proof-of-concept Study to Evaluate the Efficacy and Safety of Rozanolixizumab to Treat Adult Study Participants With Severe Fibromyalgia Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A Proof-of-concept Study to Evaluate the Efficacy and Safety of Rozanolixizumab to Treat Adult Study Participants With Severe Fibromyalgia Syndrome: primary endpoint results, effect estimate with confidence interval,…
- A Proof-of-principle Study of HBO-SRS for Brain Metastases: Complete Statistical AnalysisIndependent statistical analysis of A Proof-of-principle Study of HBO-SRS for Brain Metastases: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01850563).
- A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Prospective Study Investigating the Use of Relaxation Prior to Medical Procedures.: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Study Investigating the Use of Relaxation Prior to Medical Procedures.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief: Complete Statistical AnalysisIndependent statistical analysis of A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study): Complete Statistical AnalysisIndependent statistical analysis of A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Randomized Trial of Two Formal Group Programs for Multiple Sclerosis: Complete Statistical AnalysisIndependent statistical analysis of A Randomized Trial of Two Formal Group Programs for Multiple Sclerosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke: Complete Statistical AnalysisIndependent statistical analysis of A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel…
- A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms: Complete Statistical AnalysisIndependent statistical analysis of A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain: Complete Statistical AnalysisIndependent statistical analysis of A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain: primary endpoint results, effect estimate…
- A Registry Study to Evaluate Outcomes of PEMF Therapy in Subjects With Various Pain Etiologies: Complete Statistical AnalysisIndependent statistical analysis of A Registry Study to Evaluate Outcomes of PEMF Therapy in Subjects With Various Pain Etiologies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Research Study to Examine the Difference Between Local Anesthetics Alone and Local Anesthetics Plus Steroids in the Treatment of Chronic Headache: Complete Statistical AnalysisIndependent statistical analysis of A Research Study to Examine the Difference Between Local Anesthetics Alone and Local Anesthetics Plus Steroids in the Treatment of Chronic Headache: primary endpoint results, effect estimate with…
- A Retrospective Investigation of Local Anesthetic Concentrations in Femoral Nerve Block: Complete Statistical AnalysisIndependent statistical analysis of A Retrospective Investigation of Local Anesthetic Concentrations in Femoral Nerve Block: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]: Complete Statistical AnalysisIndependent statistical analysis of A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West…
- A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis: Complete Statistical AnalysisIndependent statistical analysis of A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention: Complete Statistical AnalysisIndependent statistical analysis of A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA): Complete Statistical AnalysisIndependent statistical analysis of A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA):…
- A Sensor-enhanced Mouth Guard to Quantitatively Measure Bite Compression Forces.: Complete Statistical AnalysisIndependent statistical analysis of A Sensor-enhanced Mouth Guard to Quantitatively Measure Bite Compression Forces.: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06688474).
- A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.: Complete Statistical AnalysisIndependent statistical analysis of A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.: primary endpoint results, effect estimate with…
- A Study Evaluating Desvenlafaxine Sustained Release (DVS SR) in Adult Female Outpatients With Fibromyalgia: Complete Statistical AnalysisIndependent statistical analysis of A Study Evaluating Desvenlafaxine Sustained Release (DVS SR) in Adult Female Outpatients With Fibromyalgia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects: Complete Statistical AnalysisIndependent statistical analysis of A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study for the Treatment of Diabetic Peripheral Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of A Study for the Treatment of Diabetic Peripheral Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00552175).
- A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): Complete Statistical AnalysisIndependent statistical analysis of A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN): Complete Statistical AnalysisIndependent statistical analysis of A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of a Mobile Phone Application Measuring the Eyes Before and After Medication: Complete Statistical AnalysisIndependent statistical analysis of A Study of a Mobile Phone Application Measuring the Eyes Before and After Medication: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Abemaciclib in Recurrent Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of A Study of Abemaciclib in Recurrent Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02981940).
- A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm: Complete Statistical AnalysisIndependent statistical analysis of A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00942851).
- A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG: Complete Statistical AnalysisIndependent statistical analysis of A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 1 of 2): Complete Statistical AnalysisIndependent statistical analysis of A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 1 of 2): primary…
- A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I): Complete Statistical AnalysisIndependent statistical analysis of A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn: Complete Statistical AnalysisIndependent statistical analysis of A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy: Complete Statistical AnalysisIndependent statistical analysis of A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy: primary endpoint results, effect estimate with confidence interval,…
- A Study of E2020 in Patients With Dementia With Lewy Bodies (DLB), Followed by a Long-term Extension Phase: Complete Statistical AnalysisIndependent statistical analysis of A Study of E2020 in Patients With Dementia With Lewy Bodies (DLB), Followed by a Long-term Extension Phase: primary endpoint results, effect estimate with confidence interval, sample-size planning…
- A Study of Fisetin to Treat Carpal Tunnel Syndrome: Complete Statistical AnalysisIndependent statistical analysis of A Study of Fisetin to Treat Carpal Tunnel Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05416515).
- A Study of Intravenous Perampanel in Japanese Participants With Epilepsy: Complete Statistical AnalysisIndependent statistical analysis of A Study of Intravenous Perampanel in Japanese Participants With Epilepsy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03754582).
- A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers: Complete Statistical AnalysisIndependent statistical analysis of A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of LY2624803 in Japanese Participants With Transient Insomnia: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY2624803 in Japanese Participants With Transient Insomnia: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01784614).
- A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer’s Disease: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain: Complete Statistical AnalysisIndependent statistical analysis of A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- A Study of Mobile Medical Supportive Care Program for Family Caregivers With Dementia Combined With Diabetes: Complete Statistical AnalysisIndependent statistical analysis of A Study of Mobile Medical Supportive Care Program for Family Caregivers With Dementia Combined With Diabetes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…