Statistical methods in neurology trials
The methods these trials rely on most, based on the statistical analyses posted to ClinicalTrials.gov, with the tutorial that explains each one.
ANCOVA
Mixed-effects model
Odds ratio
MMRM (mixed model for repeated measures)
Multiple imputation / missing data
Hazard ratio
Cochran-Mantel-Haenszel test
Non-inferiority trial design
All neurology trials
1,213 results
- Pain in Traumatic Brain Injury – Basile, MD: Complete Statistical AnalysisIndependent statistical analysis of Pain in Traumatic Brain Injury - Basile, MD: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01136486).
- Pain Management in Teeth With Reversible Pulpitis: Complete Statistical AnalysisIndependent statistical analysis of Pain Management in Teeth With Reversible Pulpitis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT07114198).
- Paracervical Block for Pain Associated With Laminaria Insertion: Complete Statistical AnalysisIndependent statistical analysis of Paracervical Block for Pain Associated With Laminaria Insertion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02454296).
- Paracetamol With Caffeine to Treat Episodic Tension Type Headache: Complete Statistical AnalysisIndependent statistical analysis of Paracetamol With Caffeine to Treat Episodic Tension Type Headache: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01755702).
- Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson’s Disease: Complete Statistical AnalysisIndependent statistical analysis of Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- PATHFINDERIIIndependent statistical analysis of Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Patient Convenience Study (RE-SONANCE): Complete Statistical AnalysisIndependent statistical analysis of Patient Convenience Study (RE-SONANCE): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02684981).
- PCORI Urea Cycle Disorder Study: Complete Statistical AnalysisIndependent statistical analysis of PCORI Urea Cycle Disorder Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02740153).
- PCTDMRTTIndependent statistical analysis of Placebo Controlled Trial of Dextromethorphan in Rett Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01520363).
- PDA+Independent statistical analysis of PDA+: A Personal Digital Assistant for Obesity Treatment: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00371462).
- PDOP_TLRIndependent statistical analysis of Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- PDPHIndependent statistical analysis of Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- PECS II vs. MTP for Analgesia After MRM: Complete Statistical AnalysisIndependent statistical analysis of PECS II vs. MTP for Analgesia After MRM: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT06187909).
- Pediatric Tonsillectomy Pain Reduction Study: Complete Statistical AnalysisIndependent statistical analysis of Pediatric Tonsillectomy Pain Reduction Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00678379).
- Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents: Complete Statistical AnalysisIndependent statistical analysis of Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer: Complete Statistical AnalysisIndependent statistical analysis of Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer: primary endpoint results, effect estimate…
- Perampanel in Seizure Patients With Primary Glial Brain Tumors: Complete Statistical AnalysisIndependent statistical analysis of Perampanel in Seizure Patients With Primary Glial Brain Tumors: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT02363933).
- PerformsIndependent statistical analysis of A Multicenter, Open-label, RebiSmart™ Autoinjector Ease of Use Study: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01036165).
- Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion: Complete Statistical AnalysisIndependent statistical analysis of Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Peripheral Dopamine in Postural Tachycardia Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Peripheral Dopamine in Postural Tachycardia Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00685919).
- Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome: Complete Statistical AnalysisIndependent statistical analysis of Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04053452).
- PersistIndependent statistical analysis of Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04433975).
- Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis: Complete Statistical AnalysisIndependent statistical analysis of Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects: Complete Statistical AnalysisIndependent statistical analysis of PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme: Complete Statistical AnalysisIndependent statistical analysis of Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- PhantomLimbIndependent statistical analysis of Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based…
- Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and…
- Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health: Complete Statistical AnalysisIndependent statistical analysis of Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01667796).
- Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer: Complete Statistical AnalysisIndependent statistical analysis of Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1): Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1): primary endpoint results, effect estimate with confidence interval,…
- Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Phase 2 Herniorrhaphy Study for Opioid Elimination: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Herniorrhaphy Study for Opioid Elimination: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03695367).
- Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma: Complete Statistical AnalysisIndependent statistical analysis of Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL): Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery: Complete Statistical AnalysisIndependent statistical analysis of Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery: primary endpoint results, effect estimate with confidence interval, sample-size…
- Phase I Trial Evaluating the Pharmacokinetics of Single Ascending Oral Doses of IRL757 in Healthy Elderly Volunteers: Complete Statistical AnalysisIndependent statistical analysis of Phase I Trial Evaluating the Pharmacokinetics of Single Ascending Oral Doses of IRL757 in Healthy Elderly Volunteers: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration,…
- Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas: Complete Statistical AnalysisIndependent statistical analysis of Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT01434602).
- Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma: Complete Statistical AnalysisIndependent statistical analysis of Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC): Complete Statistical AnalysisIndependent statistical analysis of Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC): primary endpoint results, effect estimate with confidence interval, sample-size…
- Physiologic Pacing Registry: Complete Statistical AnalysisIndependent statistical analysis of Physiologic Pacing Registry: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03719040).
- Physiological Flow of Liquids Used in Dysphagia Management (Neuro): Complete Statistical AnalysisIndependent statistical analysis of Physiological Flow of Liquids Used in Dysphagia Management (Neuro): primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT03192358).
- Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation: Complete Statistical AnalysisIndependent statistical analysis of Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Pilot Study Evaluating the Use of Nasal Carbon Dioxide for the Treatment of Cluster Headache: Complete Statistical AnalysisIndependent statistical analysis of Pilot Study Evaluating the Use of Nasal Carbon Dioxide for the Treatment of Cluster Headache: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety,…
- Pilot Study of Transcranial Stimulation (tDCS)to Relieve Neuropathic Pain in Cancer Patients: Complete Statistical AnalysisIndependent statistical analysis of Pilot Study of Transcranial Stimulation (tDCS)to Relieve Neuropathic Pain in Cancer Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov…
- Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine: Complete Statistical AnalysisIndependent statistical analysis of Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results…
- Pilot Testing of a Behavioral Intervention for Chronic Pain in Individuals With HIV: Complete Statistical AnalysisIndependent statistical analysis of Pilot Testing of a Behavioral Intervention for Chronic Pain in Individuals With HIV: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on…
- PIOGASIndependent statistical analysis of Pioglitazone for Idiopathic Gastroparesis: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT04300127).
- PITCH-EIndependent statistical analysis of Pain Inflammation and Cannabis in HIV: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT05554146).
- Pivotal Study in Advanced Parkinsons Disease Patients: Complete Statistical AnalysisIndependent statistical analysis of Pivotal Study in Advanced Parkinsons Disease Patients: primary endpoint results, effect estimate with confidence interval, sample-size planning illustration, and safety, based on ClinicalTrials.gov results (NCT00466167).